Lectures and seminars What is life-lecture & Network Medicine with George M. Spyrou, Professor at The Cyprus Institute of Neurology & Genetics

"Network-based bioinformatics approaches that highlight disease-related mechanisms and candidate repurposed drugs"

Speaker

George M. Spyrou, Bioinformatics ERA Chair, Professor and Head of the Bioinformatics Department, The Cyprus Institute of Neurology & Genetics (CING), Nicosia, Cyprus.

Prof. George M. Spyrou holds a BSc in Physics, an MSc in Medical Physics, and an MSc in Bioinformatics as well. During his Ph.D., he worked on algorithms and simulations focusing on breast imaging. Since 2017, Dr. Spyrou is the Bioinformatics Course Coordinator at the Postgraduate School of CING where he has been elected as a full Professor in 2019. He is also a visiting instructor on thematic areas including Systems Bioinformatics, Biological Network Analysis, and Biomedical Informatics in other undergraduate and postgraduate courses. Dr. Spyrou is a Senior IEEE Member and a Member of the Steering Committee for the creation of the European Bioinformatics Infrastructure ELIXIR-Cyprus

Hosts

Andrey Alexeyenko & Ingemar Ernberg, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet

Abstract

Network science, together with machine learning and computational modeling, lays out a roadmap for the further development of bioinformatics towards a more efficient exploitation of single-level omics as well as multi-omics. Network-based inference and integration provide great opportunities to develop innovative methodologies that lead to new insights into the discovery of candidate repurposed drugs and disease-related mechanisms. Network-based methods and tools for mechanism understanding and drug repurposing, developed by C-BIG, the Bioinformatics Department at CING, will be presented.