Lectures and seminars Webinar: Optimizing Animal Model Selection for Human Translation: The Animal Model Quality Assessment
The aim of these CPD webinars (Continuing professional development) is to follow the legal requirements for maintenance and demonstration of competence in laboratory animal science, and to facilitate the implementations of the 3R’s in routine animal work.
Alan Olzinski, Associate Director, Animal Research Strategy Group, Office of Animal Welfare, Ethics, Strategy and Risk, GlaxoSmithKline, Collegeville, PA, USA.
Register here (by May 3, 16.00 CET)
Animal studies in pharmaceutical drug discovery are common in preclinical research for compound evaluation before progression into human clinical trials. However, high rates of drug development attrition have prompted concerns regarding animal models and their predictive translatability to the clinic.
To improve the characterization and evaluation of animal models for their translational relevance, this presentation will describe a tool that was developed to transparently reflect key features of a model that may be considered in both the application of and likelihood of successful translation of the outcomes for human patients.
The presentation will describe the rationale for the development of the Animal Model Quality Assessment tool, the questions used for the animal model assessment, and a high-level scoring system to define predictive translatability.