Lectures and seminars SFOepi Seminar Series in Biostatistics: Karl-Oskar Ekvall, University of Florida

22-05-2025 10:00 am - 11:00 am Add to iCal
Campus Solna Lecture hall Atrium (this event is not online), Nobels väg 12B, Solna

Title: Reliable inference in mixed models

Please note that this event is not filmed nor streamed – only participation in person.

Abstract

Mixed models, and random effects in particular, are used routinely to model data with dependent observations and effect heterogeneity. However, while random effects are convenient for specifying a model, they often complicate inference. As a result, popular software for statistical analysis often does not provide confidence intervals for random effect parameters by default, or worse, provide provably unreliable ones. This talk discusses the challenges, with particular focus on the difficulties with inference on random effect parameters, and possible solutions. The results are illustrated using a variance components model common in genetics and genomics, but extensions to more complicated mixed models are also discussed.

Registration: No registration is needed

If you have any questions, please contact Marie Jansson at marie.jansson@ki.se