Lectures and seminars Sfo Epi Seminar in Biostatistics: Professor Marco Bonetti
Welcome to attend the SfoEpi Seminar Series in Biostatistics!
Title: Statistical models for the natural history of breast cancer: likelihood and likelihood-free estimation
Speaker: Professor Marco Bonetti, Bocconi University, Milan, Italy
Zoom Link: https://ki-se.zoom.us/j/69572592804
*Webinar format: unless you are on the panel you will be muted and with no video. Participants can raise their hands during the Q&A to be recognized to ask questions.
We discuss and implement some models for the natural history of breast cancer, where the main events of interest are the start of asymptomatic detectability of the disease and the start of symptomatic detectability. The former kind of detection occurs through screening, while the latter through the emergence of symptoms. We describe two tractable models for which we perform maximum likelihood inference on the underlying process and more flexible models for which we rely on Approximate Bayesian Computation (ABC) for estimation. We present some preliminary results of the analysis of data collected as part of a motivating study from Milan, merged with administrative data from the Italian national health care system. Lastly, we discuss some issues associated with the use of ABC.
If you have any questions, please contact Erin Gabriel.