Lectures and seminars Seminar: "Molecular, anatomical, and functional diversity of midbrain dopamine neurons"

Focus of Work

Bio

1. Mechanisms underlying dopamine neuron development, function, diversity, and degeneration. 

2. Mechanisms regulating peripheral nerve myelination in development and disease states.

Most Recent Publications

Implementation and validation of single-cell genomics experiments in neuroscience

Colonna M, Konopka G, Liddelow SA, Nowakowski T, Awatramani R, Bateup HS, Cadwell CR, Caglayan E, Chen JL, Gillis J, Kampmann M, Krienen F, Marsh SE, Monje M, O’Dea MR, Patani R, Pollen AA, Quintana FJ, Scavuzzo M, Schmitz M, Sloan SA, Tesar PJ, Tollkuhn J, Tosches MA, Urbanek ME, Werner JM, Bayraktar OA, Gokce O, Habib N. 
Nature Neuroscience. 2024 Dec; 27(12): 2310-2325. https://doi.org/10.1038/s41593-024-01814-0 
PMID: 39627589 ISSN: 1097-6256

miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network.

Pulcrano S, De Gregorio R, De Sanctis C, Volpicelli F, Piscitelli RM, Speranza L, Perrone-Capano C, di Porzio U, Caiazzo M, Martini A, Giacomet C, Medina D, Awatramani R, Viggiano D, Federici M, Mercuri NB, Guatteo E, Bellenchi GC
J Neurosci. 2023 Nov; 43(48): 8104-8125. https://doi.org/10.1523/JNEUROSCI.0431-23.2023
PMID: 37816598

Unique functional responses differentially map onto genetic subtypes of dopamine neurons.

Azcorra M, Gaertner Z, Davidson C, He Q, Kim H, Nagappan S, Hayes CK, Ramakrishnan C, Fenno L, Kim YS, Deisseroth K, Longnecker R, Awatramani R, Dombeck DA. 
Nat Neurosci. 2023 Oct; 26(10): 1762-1774. https://doi.org/10.1038/s41593-023-01401-9
PMID: 37537242

Stem cell decoupling underlies impaired lymphoid development during aging.

Jang G, Contreras Castillo S, Esteva E, Upadhaya S, Feng J, Adams NM, Richard E, Awatramani R, Sawai CM, Reizis B
Proc Natl Acad Sci U S A. 2023 May; 120(22): e2302019120-. https://doi.org/10.1073/pnas.2302019120
PMID: 37216517