Lectures and seminars Seminar: “Dynamic control of the integrated stress response by RNA viruses: from cells to droplets”
Welcome to a opponent seminar with Alessia Ruggieri, Department of Infectious Diseases, Molecular Virology,
Heidelberg University, Medical Faculty Heidelberg, Germany.
Title
“Dynamic control of the integrated stress response by RNA viruses: from cells to droplets”
Speaker
Alessia Ruggieri, Department of Infectious Diseases, Molecular Virology, Heidelberg University, Medical Faculty Heidelberg, Germany
Alessia Ruggieri is the opponent at Siwen Longs doctoral thesis defence; "Mechanisms and Targets in SARS-CoV-2: From Viral Protein Interactions to Antiviral Strategies".
Selected Publications
Magg V, Manetto A, Kopp K, Wu C, Lindner D, Naghizadeh M, Schott J, Eke L, Welsch J, Kallenberger SM, Haucke V, Locker N, Stoecklin G†, Ruggieri A†. Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress. 2024. Cell Reports 43(4):114069. Link to paper
Klein P, Kallenberger SM, Roth H, Roth K, Ly-Hartig TBN, Magg V, Aleš J, Talemi SR , Qiang Y, Wolf S, Oleksiuk O, Kurilov R, Di Ventura B, Bartenschlager R, Eils R, Rohr K, Hamprecht FA, Höfer T, Fackler OT, Stoecklin G, Ruggieri A. Temporal control of the integrated stress response by a stochastic molecular switch. 2022. Science Advances 8(12):eabk2022. Link to paper
Ruggieri A, Dazert E, Metz P, Hofmann S, Bergeest JP, Mazur J, Bankhead P, Hiet MS, Kallis S, Alvisi G, Samuel CE, Lohmann V, Kaderali L, Rohr K, Frese M, Stoecklin G, Bartenschlager R. Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection. 2012. Cell Host Microbe 12(1): 71-85. Link to paper
Host
Gerald McInerney, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet