Lectures and seminars Processing of nociceptive peripheral input in spinal cord networks

13-05-2024 10:00 am Add to iCal
Faculty club, 10th floor

Prof. Pavel Belan
Department of Molecular Biophysics,, Bogomoletz Institute of Physiology & Kyiv Academic University, Ukraine

Studies of general principles of pain processing are very important for better understanding both the physiology of nociception and pathology of pain syndromes. It is well-known that somatic painful stimuli induce action potential in peripheral receptors of dorsal root ganglion (DRG) neurons. These APs propagate to the spinal cord resulting in its activity further transduced to supraspinal structures and finally to the cortex where the emotion of pain is formed. In our work, we have cantered on a better understanding of processing of peripheral afferent input from the DRG neurons by dorsal horn networks and descending pathways using ex-vivo electrophysiology.