Lectures and seminars Oxidative regulation of autoimmunity

Lunch sandwiches will be offered from 12:00 on a first come-first served basis. Welcome!

Speaker:  

Professor Rikard Holmdahl, Karolinska Institutet,
Department of Medical Biochemistry and Biophysics

Host:               

Professor Vivianne Malmström
Karolinska Institutet, Departement of Medicine
Center for Molecular Medicine, CMM

NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus.
Linge P, Arve S, Olsson LM, Leonard D, Sjöwall C, Frodlund M, et al
Ann. Rheum. Dis. 2019 Nov;():

Low Production of Reactive Oxygen Species Drives Systemic Lupus Erythematosus.
Urbonaviciute V, Luo H, Sjöwall C, Bengtsson A, Holmdahl R
Trends Mol Med 2019 Oct;25(10):826-835

Analyses of association of psoriatic arthritis and psoriasis vulgaris with functional NCF1 variants.
Löhr S, Ekici AB, Uebe S, Büttner C, Köhm M, Behrens F, et al
Rheumatology (Oxford) 2019 May;58(5):915-917

Cutting Edge: Processing of Oxidized Peptides in Macrophages Regulates T Cell Activation and Development of Autoimmune Arthritis.
Yang M, Haase C, Viljanen J, Xu B, Ge C, Kihlberg J, et al
J. Immunol. 2017 12;199(12):3937-3942

A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus.
Olsson LM, Johansson ÅC, Gullstrand B, Jönsen A, Saevarsdottir S, Rönnblom L, et al
Ann. Rheum. Dis. 2017 Sep;76(9):1607-1613