Conferences and symposiums Mini-symposium: Vascular Immunity, Inflammation and Atherosclerosis

27-01-2022 1:30 pm Add to iCal

The present mini-symposium offers an update of the progress in the field of vascular immunity, inflammation and atherosclerosis that has been achieved in recent years. It includes lectures by internationally recognized investigators who will highlight new developments and knowledge in basic, translational and clinical sciences of the mechanisms that promote migration of leukocytes into inflamed tissue, and the consequences of those interactions for the promotion and regression of inflammation

The symposium celebrates Professor Göran K Hansson's recent landmark birthday

Some 35 years ago Professor Göran K Hansson, his then graduate student Lena Jonasson, and colleagues discovered the presence of T lymphocytes in human atherosclerotic plaques. Their foundational observation set the stage for over three decades of sustained exploration of immunity and inflammation in atherosclerosis. This field has burgeoned, matured, and has reached the stage of clinical translation.

Atherosclerosis, a chronic inflammatory disease of the arteries, has life-threatening complications, myocardial and cerebral infarcts, two primary causes of death. In pathology, atherosclerosis is characterized by the formation of lipid-laden, fibrous plaques in the intima of the arterial wall, a long-lasting process with years of interplays between lipid deposition, inflammatory infiltration, smooth muscle cell migration and transformation, and fibrotic tissue accumulation. Although the inflammatory property of atherosclerotic plaques was described more than a century ago, a mechanistic understanding of the role of innate and adaptive immunity in atherogenesis has emerged in the last few decades. The symposium offers an update in the field and celebrates Professor Göran K Hansson's recent landmark birthday. 

Confirmed Speakers:

Göran K Hansson (Karolinska Institutet):  Frying fat in the artery wall - Immune inflammation triggered by LDL

Peter Libby (Harvard Medical School and Brigham and Women’s Hospital, Boston, MA, USA): Immunity and inflammation in atherosclerosis-no longer just a theory

Yong-Jian Geng (University of Texas Health Science Center at Houston, USA):  Oxidative lipid induction of immune responses and inflammation in atherosclerosis

Lena Jonasson (Linköping University, Sweden):  T cell aging in coronary artery disease

Marc Feldmann (Kennedy Institute of Rheumatology, University of Oxford, UK):  Challenges in discovering therapeutic targets

Jan Nilsson (Lund University, Sweden):   Active and passive immunization targeting apoB antigens

Daniel Ketelhuth (University of Southern Denmark, Denmark and Karolinska Institutet):   Targeting immunometabolism in cardiovascular diseases

Esther Lutgens (University of Amsterdam, Netherlands):   Agonistic immune checkpoints: target - mechanism – therapy

Giuseppina Caligiuri (University Hospital Xavier Bichat, Paris, France):   CD31 as a therapeutic target in atherosclerosis

Norbert Gerdes (University Hospital Düsseldorf, Düsseldorf, Germany):   The co-stimulatory axis CD40/CD40L in cellular crosstalk in CVD

Peder S Olofsson (Karolinska Institutet):   Understanding inflammation requires neuroscience


January 27, 2022, between 1.30 and 6.30 P.M. (CET), or 7.30 A.M. and 12.30 P.M. (US East coast time).


The mini-symposium will be held entirely on-line via Zoom. . Access link will be sent to the registered participants and will be published on the website of the Karolinska Institutet


This is a free event. Participants register by sending their name, and information about their title, affiliation to:

Organizing committee:

Peder S Olofsson, Karolinska Institutet, Sweden

Lena Jonasson, Linköping University, Sweden

Peter Libby, Harvard Medical School and Brigham and Women’s Hospital, Boston, MA, USA

Yong-Jian Geng, University of Texas Health Science Center at Houston, USA

Anton Gisterå, Karolinska Institutet, Sweden


The Journal of Internal Medicine

International Society of Atherosclerosis

North American Vascular Biology Organization