Lectures and seminars KI Infection Biology Network Seminar: ”Legionella, amoeba, humans: a menage à trois”
Welcome to a seminar with Professor Carmen Buchrieser from Institut Pasteur, France: ”Legionella, amoeba, humans: a menage à trois”. Join us for coffee and mingle from 12.45!
Speaker
Professor Carmen Buchrieser, Institut Pasteur, France
Biography of Professor Carmen Buchrieser
Carmen Buchrieser is currently Professor at the Institut Pasteur, Paris, France. She obtained her PhD from the University Salzburg, Austria, conducted postdoctoral trainings at the University of Madison, Wisconsin, USA and at the Institut Pasteur, Paris France. She is heading a research group at the Intitut Pasteur studying bacterial pathogenesis. Her major research interest is to understand how bacteria cause disease: what are the genetic factors conferring bacterial virulence, how do they evolve, what are the mechanisms by which they allow subverting host functions and more generally how do human pathogens emerge. Her team uses Legionella as a model, as these bacteria are at the crossroad between an environmental bacterium (parasite of protozoa) and a human pathogen (replicating in alveolar macrophages).
Selected publications
Schator D, Mondino S, Berthelet J, Di Silvestre C, Ben Assaya M, Rusniok C, Rodrigues-Lima F, Wehenkel A, Buchrieser C*, Rolando M* (2023) Legionella para-effectors target chromatin and promote bacterial replication. Nat Commun 14;14(1):2154. doi: 10.1038/s41467-023-37885-z
SahrT, Escoll P, Rusniok C, Bui S, Pehau-Arnaudet G, Lavieu G, Buchrieser C (2022) Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs to dampen the host immune response. Nature Communications, 13(1):762 doi: 10.1038/s41467-022-28454-x
Mondino S, Schmidt S, Rolando M, Escoll P, Gomez-Valero L, Buchrieser C (2020) Legionnaires' Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella. Annu Rev Pathol. 15:439-466
Gomez-Valero L, Rusniok C, Carson D, Mondino S, Pérez-Cobas AE, Rolando M, Pasricha S, Reuter S, Demirtas J, Crumbach J, Descorps-Declere S, Hartland EL, Jarraud S, Dougan G, Schroeder GN, Frankel G, Buchrieser C. (2019) More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells. Proc Natl Acad Sci U S A. 116(6):2265-2273.
Rolando M, Sanulli S, Rusniok C, Gomez-Valero L, Bertholet C, Sahr T, Margueron R, Buchrieser C. (2013) Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication. Cell Host & Microbe 13(4):395-405
Title
”Legionella, amoeba, humans: a menage à trois”
Host
The KI Infection Biology Network
For participation online
Meeting ID: 643 1849 5676