Lectures and seminars Joint MTC, CMM, CID Seminar: "Cell wall biosynthesis as a target (novel) antibiotics"
Welcome to a joint MTC, CMM and CID seminar with Tanja Schneider, Institute for Pharmaceutical Microbiology, University of Bonn, Germany.
"Cell Wall Biosynthesis as a Target for (Novel) Antibiotics"
Tanja Schneider, Institute for Pharmaceutical Microbiology, University of Bonn, Germany.
Tanja Schneider is a leading scientist in the field of antibiotic development and characterization. She was part of the study that identified the ’new’ antibiotic teixobactin and her lab is focused on identification and characterization of novel cell wall targeting compounds.
A new antibiotic kills pathogens without detectable resistance.
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, et al
Nature 2015 Jan;517(7535):455-9
Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus.
Rausch M, Deisinger JP, Ulm H, Müller A, Li W, Hardt P, et al
Nat Commun 2019 03;10(1):1404
The cell wall precursor lipid II acts as a molecular signal for the Ser/Thr kinase PknB of Staphylococcus aureus.
Hardt P, Engels I, Rausch M, Gajdiss M, Ulm H, Sass P, et al
Int. J. Med. Microbiol. 2017 Jan;307(1):1-10
Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.
Schneider T, Kruse T, Wimmer R, Wiedemann I, Sass V, Pag U, et al
Science 2010 May;328(5982):1168-72