Lectures and seminars IMM Seminar: Two studies on elderly covid-19 patients

The ‘Frailty and mortality of hospitalized elderly COVID-19 patients’ topic is about a prognostic study of the frailty status assessed by hospital frailty risk score (HFRS) and frailty index (FI) and  fatality risk among elderly COVID-19 patients aged ≥65 years old hospitalized in Wuhan Tongji Hospital from 27^th Jan. 2020 to 16^th Feb. 2020. Multivariable Cox proportional hazard regression model and Prognostic model were mainly used. It was concluded that frailty was positively associated with mortality risk in elderly COVID-19 patients; and frailty in combination with other demographic and clinical indicators are predictive of COVID-19 prognosis among the elderly patients. 

The ‘One-year physical and mental health of cured older COVID-19 patients’ study is to evaluate potential post-COVID-19 sequalae one year after infections among older individuals aged ≥60 years old in the first wave of epidemic. All patients were discharged from hospital between Dec 8, 2019 and Apr 8, 2020. Lung function was mainly determined for physical health assessment; and posttraumatic stress, depression, anxiety, insomnia, etc. were mainly determined for mental health assessment. It was found that severe patients had more headaches, chest pain, gastrointestinal symptoms, etc.; smell, sleep, and other functions more impaired in severe cases; poorer mental health and sleep quality in severe patients; and some severe patients had persisting abnormal lung function.