Lectures and seminars Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms
Professor Eleonora Candi will talk about their research on p63 in skin development and their most recent findings about how extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
Professor in Molecular Biology at the Faculty of Medicine of the University of Rome Tor Vergata.
Ning Xu Landén
Associate professor at Karolinska Institutet, Department of Medicine Solna, Division of Dermatology and Venerology, Center for Molecular Medicine.
Eleonora Candi received her Ph.D. in Biochemistry of the Epithelia in 1995 (Rome, Italy). Thereafter, she did her post-doctoral training at the National Institute of Health (NIH), Bethesda, MD, USA, working on transglutaminases and their substrates. In 2017, she became a Full Professor in Molecular Biology at the Faculty of Medicine of the University of Rome Tor Vergata. She is an editorial board member of Cell Death & Disease and The FEBS Journal. She has been working on cell death, both apoptosis and keratinization in the past years. Her current scientific interest includes the role of p63 in epithelia development and tumor formation, epigenetic modifications, miRNAs, and lncRNAs.
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
Cappello A, Mancini M, Madonna S, Rinaldo S, Paone A, Scarponi C, Belardo A, Zolla L, Zuccotti A, Panatta E, Pallotta S, Annicchiarico-Petruzzelli M, Albanesi C, Cutruzzolà F, Wang L, Jia W, Melino G, Candi E
Sci Adv 2022 Dec;8(50):eabm7902
The p63 C-terminus is essential for murine oocyte integrity.
Lena AM, Rossi V, Osterburg S, Smirnov A, Osterburg C, Tuppi M, Cappello A, Amelio I, Dötsch V, De Felici M, Klinger FG, Annicchiarico-Petruzzelli M, Valensise H, Melino G, Candi E
Nat Commun 2021 Jan;12(1):383
Long non-coding RNA uc.291 controls epithelial differentiation by interfering with the ACTL6A/BAF complex.
Panatta E, Lena AM, Mancini M, Smirnov A, Marini A, Delli Ponti R, Botta-Orfila T, Tartaglia GG, Mauriello A, Zhang X, Calin GA, Melino G, Candi E
EMBO Rep 2020 Mar;21(3):e46734