Lectures and seminars Crossing borders seminar with Maria Asplund, Chalmers University of Technology

04-03-2024 4:00 pm - 5:00 pm Add to iCal
Campus Solna Peter Reichard, floor 3, Biomedicum, Solnavägen 9, Solna

"Bioelectronic microsystems engineering: for patients, for cyborgs and for neuroscientists at work"

Welcome to a Crossing borders hybrid seminar with Maria Asplund, Chalmers University of Technology, on Monday 4 March 2024 in Biomedicum, Solna. You can also join via Zoom (register via link).

Abstract

Bioelectronic medicine use electrical signals, either recorded from or injected into tissue, to reach a therapeutic effect. Over the last ten years, enormous progress has been made to increase the precision at which bio/ and neuro-electronics can operate. These developments allow us to break new ground, for instance within neurotechnology for sensory restoration directly targeting the brain. In the first part of my talk, I will give my perspective on where we currently stand with such brain interfaces and give an overview of relevant design considerations from an engineering perspective. I will further discuss challenges that need to be overcome before high-resolution brain interfaces truly can benefit patients. 

Until recently, research efforts have predominantly centered on bioelectronics tailored for the nervous system, inadvertently neglecting the broader potential of bioelectronic medicine across diverse tissue types. While excitable cells respond to swift changes in potential, continuous electric fields and direct current engage subtler bioelectrical mechanisms that are not exclusive to neurons. For instance, electric fields can influence cellular migration and growth, rendering electrical field stimulation relevant for orchestrating regenerative processes. This deserves more attention but may require re-thinking old truths within electrode design. In the second part of my talk, I will expand upon our ongoing endeavors in bioelectronic wound healing and spinal cord repair, wherein we leverage electrical fields as guidance cues. 

Finally, I will discuss how these engineering solutions already contribute to the work of neuroscientists, supporting higher accuracy and reproducibility in their electrophysiological exploration.

Host

Anna Herland, Karolinska Institutet, Department of Neuroscience/AIMES

Crossing borders is a webinar series focusing on interdisciplinary sciences, organised in collaboration with KTH Royal Institute of Technology.

Contact

Linda Thörn Operations Controller