Lectures and seminars Annual lecture in structural biology by Jennifer Lippincott-Schwartz
Jennifer Lippincott-Schwartz from the Howard Hughes Medical Institute will give the lecture entitled ‘Emerging Imaging Technologies to Study Cell Architecture, Dynamics, and Function’ on Monday 8th November 2021 at 4.00pm in the Biomedicum lecture theatre. Using cutting-edge, superresolution imaging technology to visualize cellular activity at the nano-scale, Lippincott-Schwartz lab has redefined how we look at protein dynamics in the cell.
The annual lecture series is set up in the recognition of the development of electron microscopy and will be delivered by eminent scientists in the field of structural biology and molecular visualisation. The event is open to anyone. A holder of the lectureship will particularly spend time with students and postdocs. Therefore, Jennifer will also give an account of her career path and discuss with students and postdocs at 09.30 am in the SciLifeLab Air&Fire auditorium.
About Jennifer Lippincott-Schwartz
Research in Lippincott-Schwartz lab is aimed at developing live cell imaging to elucidate the dynamics inside eukaryotic cells. She pioneered photobleaching and photoactivation techniques which allow investigation of subcellular localization, turnover and trafficking of important cellular proteins related to membrane compartmentalization. Her work on photoactivatable GFP led to the development of one of the first super-resolution imaging technologies, photoactivation localization microscopy. Jennifer then used her methods to assess organelles dynamics and interactions revealing a novel picture of how the peripheral endoplasmic reticulum is structured. In addition, the Golgi apparatus is central to Jennifer’s studies, where her team demonstrated a novel pathway of enzymes recycling important for the organelle’s biogenesis and maintenance. Together, the obtained findings have provided insights into how genetic diseases affect proteins that help shape the endoplasmic reticulum.
In 2016, Lippincott-Schwartz initiated the Neuronal Cell Biology Program at Janelia. She is Fellow of the American Academy of Arts and Sciences Fellow, and also Honorary Fellow of the Royal Microscopical Society.
The annual lecture in structural biology is named in honour of Fritiof Sjöstrand, who pioneered the electron microscopy in Sweden. In the early 1950’s he developed an advanced microtome for thin sectioning, and by applying it for structural analysis of mitochondria produced a major breakthrough with the determination of the double membrane system. He then engineered a next generation of microtomes using electrical heating of the specimen to advance it toward the knife, and the instrument became known as the ‘‘Sjöstrand Ultramicrotome”. In 1959, Fritiof Sjöstrand moved to UCLA, where his research focused on mitochondrial membranes and retinal synapses. Fritiof Sjöstrand founded and was Editor in Chief of the Journal of Structural Biology for 33 years. Lectures in the previous years were given by Venki Ramakrishnan and Jennifer Doudna.