Anna Wredenberg receives The Ascending Investigator Grant from Novo Nordisk
Anna Wredenberg, Principal researcher in the Division of Molecular Metabolism at the Department of Medical Biochemistry and Biophysics at KI, has received a grant from Novo Nordisk; the Ascending Investigator Grant - Endocrinology and Metabolism 2023.
Congratulations Anna! What is your project about?
- Cellular metabolism describes the chemical reactions in our cells that sustain life. The mitochondrial network, a dynamic structure inside our cells, is important in these reactions. Mitochondria may be best known for their role in energy metabolism, converting food into usable energy. But many other cellular pathways, such as glucose, lipid, amino acid, or nucleotide metabolism, enter or pass through mitochondria. It is therefore not surprising that mitochondrial dysfunction is a common feature in numerous rare inherited diseases and a contributing factor in several more common conditions. There are no effective treatment strategies for mitochondrial dysfunction, mainly due to our lack of understanding of some basics of mitochondrial biology, but also because of the complexity of cellular metabolism. This project will identify and target cellular pathways to improve the diagnosis and treatment of mitochondrial dysfunction, says Anna Wredenberg.