BEGIN:VCALENDAR VERSION:2.0 PRODID:-//ki.se//NONSGML Event Calendar//EN CALSCALE:GREGORIAN METHOD:PUBLISH BEGIN:VEVENT DTSTART:20260818T103000Z DTEND:20260818T113000Z DTSTAMP:20260810T203906Z UID:241234 DESCRIPTION:Welcome to a new seminar in the StratRegen Lunch Seminar Series on TUESDAY the 18th of August 2026\, 12.30-13.30 in seminar room Ragnar Granit\, Biomedicum\, Campus Solna.\r\n\r\nTitle: Glial rejuvenation using trans-glymphatic delivery of gene therapeutics&\;nbsp\;&\;nbsp\;Speaker:&\;nbsp\;Prof. Steven A. Goldman\, University of Copenhagen/University of RochesterGoldman lab Rochester&\;nbsp\;Center for Translational Neuromedicine\, Copenhagen\r\n\r\nSteven A. Goldman is Professor of Neuroscience and Neurology at the University of Copenhagen\, where he is Co-Director of its Center for Basic and Translational Neuroscience\, and a consultant at Copenhagen University Hospital. He has a secondary appointment at the University of Rochester in the US\, where he is the URMC Distinguished Professor and Co-Director of its Center for Translational Neuromedicine. He moved to Copenhagen in 2014 from Rochester\, having received the Novo Nordisk Laureate Award from the Novo Nordisk Fondation in Denmark. He was recruited to Copenhagen to establish its new Center in Basic and Translational Neuroscience. Goldman is a summa cum laude graduate of the University of Pennsylvania\, with BA degrees in Biology and Psychology. He obtained his PhD with Fernando Nottebohm at the Rockefeller University in 1983\, and his MD from Cornell in 1984. Goldman interned in Medicine (1984-85) and did his residency in Neurology (1985-88) at New York Hospital-Cornell and Memorial Sloan-Kettering Cancer Center. He joined the Cornell faculty in 1988\, and became a tenured Professor in 1997\, at age 39\; he is board certified in neurology and neuro-oncology. He moved to Rochester in 2003.Currently\, his laboratory seeks to use neural precursor cells to repair the damaged or dysfunctional brain and spinal cord. In previous studies\, he and his colleagues discovered that the human forebrain harbors persistent neural progenitor cells\, in both the ventricular epithelium and brain parenchyma. They have since identified discrete neurotrophic agents that act upon these adult neuronal and oligodendroglial progenitor cells to yield their expansion and differentiation. Among the studies he is collaborating on is one that would be the first transplantation of native progenitor cells into the damaged central nervous system (CNS). If successful\, these studies should provide a firm foundation for clinical trials of neural stem cell-based therapy. Goldman'\;s lab is also attempting to better define the cell types and molecules involved in cell migration in adult brain tissue. Only by better understanding this process will it be possible to modulate the destinations of implanted or induced brain cells. In all of this work\, the goal is to induce neuronal and oligodendrocytic recruitment in otherwise non-regenerative regions of the adult brain and spinal cord\, and to develop these strategies as therapeutic modalities.&\;nbsp\;\r\n\r\nPublicationsCharting the transition from in vitro gliogenesis to the in vivo maturation of human glial progenitor cells transplanted into the hypomyelinated mouse brain.Mariani JN\, Schanz SJ\, Mansky B\, Wei X\, Long CC\, Chandler-Militello D\, Aichelman HE\, Huynh NPT\, Goldman SANat Commun 2026 Apr\;():In vivo selection and glymphatic delivery of AAV5 capsids engineered to target human glial progenitor cells.Cona A\, Newbold E\, Kesmen D\, Snape R\, Danner J\, White N\, Borden W\, Iseson A\, Schanz SJ\, Chandler-Militello D\, Li X\, Cano JC\, Mariani JN\, Nedergaard M\, Benraiss A\, Goldman SAbioRxiv 2025 Jul\;():Repression of developmental transcription factor networks triggers aging-associated gene expression in human glial progenitor cells.Mariani JN\, Mansky B\, Madsen PM\, Salinas D\, Kesmen D\, Huynh NPT\, Kuypers NJ\, Kesel ER\, Bates J\, Payne C\, Chandler-Militello D\, Benraiss A\, Goldman SANat Commun 2024 May\;15(1):3873Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain.Vieira R\, Mariani JN\, Huynh NPT\, Stephensen HJT\, Solly R\, Tate A\, Schanz S\, Cotrupi N\, Mousaei M\, Sporring J\, Benraiss A\, Goldman SANat Biotechnol 2024 May\;42(5):719-730Human ESC-Derived Chimeric Mouse Models of Huntington'\;s Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation.Osipovitch M\, Asenjo Martinez A\, Mariani JN\, Cornwell A\, Dhaliwal S\, Zou L\, Chandler-Militello D\, Wang S\, Li X\, Benraiss SJ\, Agate R\, Lampp A\, Benraiss A\, Windrem MS\, Goldman SACell Stem Cell 2019 Jan\;24(1):107-122.e7&\;nbsp\;Sandwiches and coffee will be provided.\r\n\r\nHost\nGonçalo Castelo-Branco\n Professor\n Phone: +46852487936\n Email: goncalo.castelo-branco@ki.se\r\n\r\nEnric Llorens Bobadilla\n Assistant Professor\n Email: enric.llorens@ki.se\r\n\r\nElif Eroglu\n Principal Researcher\n Email: elif.eroglu@ki.se\r\n\r\nStratRegen supports researchers\, research programs and infrastructure at the Karolinska Institutet (KI) within the field of stem cells and regenerative medicine based on scope\, quality\, and the potential to strengthen and develop the field.\r\n\r\nPlease note that location\, time and information can be updated on the website.\r\nhttps://news.ki.se/calendar/stratregen-seminar-series-with-steven-a-goldman CREATED:20260625T114302Z LAST-MODIFIED:20260625T115331Z STATUS:CONFIRMED SUMMARY:StratRegen Seminar Series with Steven A. Goldman END:VEVENT BEGIN:VEVENT DTSTART:20260902T101500Z DTEND:20260902T111500Z DTSTAMP:20260810T203906Z UID:241652 DESCRIPTION:Welcome to a new seminar in the StratRegen Lunch Seminar Series on Wednesday the 2nd of September 2026\, 12.15-13.15 in seminar room Ragnar Granit\, Biomedicum\, Campus Solna.\r\n\r\nTitle: Hippocampal neurogenesis across the postnatal lifespan and across species&\;nbsp\;&\;nbsp\;Speaker:&\;nbsp\; Hongjun Song\,&\;nbsp\;David J. Mahoney Professor of Neurological Science\, Chair of the Department of Neuroscience\, University of Pennsylvania Perelman School of MedicineSong lab webpage\r\n\r\nPublicationsBrain-wide neuronal circuit connectome of human glioblastoma.Sun Y\, Wang X\, Zhang DY\, Zhang Z\, Bhattarai JP\, Wang Y\, Park KH\, Dong W\, Hung YF\, Yang Q\, Zhang F\, Rajamani K\, Mu S\, Kennedy BC\, Hong Y\, Galanaugh J\, Sambangi A\, Kim SH\, Wheeler G\, Gonçalves T\, Wang Q\, Geschwind DH\, Kawaguchi R\, Viaene AN\, Helbig I\, Kessler SK\, Hoke A\, Wang H\, Xu F\, Binder ZA\, Isaac Chen H\, Pai EL\, Stone S\, Nasrallah MP\, Christian KM\, Fuccillo M\, Toni N\, Wu Z\, Cheng HJ\, O'\;Rourke DM\, Ma M\, Ming GL\, Song HNature 2025 May\;641(8061):222-231m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice.Shen Y\, Wong SZH\, Ma T\, Zhang F\, Wang Q\, Kawaguchi R\, Geschwind DH\, Wang J\, He C\, Ming GL\, Song HCell Stem Cell 2025 May\;32(5):727-743.e8Molecular landscapes of human hippocampal immature neurons across lifespan.Zhou Y\, Su Y\, Li S\, Kennedy BC\, Zhang DY\, Bond AM\, Sun Y\, Jacob F\, Lu L\, Hu P\, Viaene AN\, Helbig I\, Kessler SK\, Lucas T\, Salinas RD\, Gu X\, Chen HI\, Wu H\, Kleinman JE\, Hyde TM\, Nauen DW\, Weinberger DR\, Ming GL\, Song HNature 2022 Jul\;607(7919):527-533A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis.Berg DA\, Su Y\, Jimenez-Cyrus D\, Patel A\, Huang N\, Morizet D\, Lee S\, Shah R\, Ringeling FR\, Jain R\, Epstein JA\, Wu QF\, Canzar S\, Ming GL\, Song H\, Bond AMCell 2019 Apr\;177(3):654-668.e15Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation.Yoon KJ\, Ringeling FR\, Vissers C\, Jacob F\, Pokrass M\, Jimenez-Cyrus D\, Su Y\, Kim NS\, Zhu Y\, Zheng L\, Kim S\, Wang X\, Doré LC\, Jin P\, Regot S\, Zhuang X\, Canzar S\, He C\, Ming GL\, Song HCell 2017 Nov\;171(4):877-889.e17&\;nbsp\;Sandwiches and coffee will be provided.\r\n\r\nHost\nEnric Llorens Bobadilla\n Assistant Professor\n Email: enric.llorens@ki.se\r\n\r\nElif Eroglu\n Principal Researcher\n Email: elif.eroglu@ki.se\r\n\r\nStratRegen supports researchers\, research programs and infrastructure at the Karolinska Institutet (KI) within the field of stem cells and regenerative medicine based on scope\, quality\, and the potential to strengthen and develop the field.\r\n\r\nPlease note that location\, time and information can be updated on the website.\r\nhttps://news.ki.se/calendar/stratregen-seminar-series-with-hongjun-song CREATED:20260803T071538Z LAST-MODIFIED:20260803T071537Z STATUS:CONFIRMED SUMMARY:StratRegen Seminar Series with Hongjun Song END:VEVENT BEGIN:VEVENT DTSTART:20260924T130000Z DTEND:20260924T140000Z DTSTAMP:20260810T203906Z UID:241706 DESCRIPTION:This is part of the “Hot-topics in multimodal imaging” seminar series hosted by the Division of Imaging Core Facilities at the department of Clinical Neuroscience.\r\n\r\nTitle: Synuclein-based biomarkers:&\;nbsp\;What they do and do not tell usSpeaker: Andrew Siderowf\, MD\, MS\, is the Hurtig-Stern Professor of Neurology and Chief of the Movement Disorders Division in the Department of Neurology at the Perelman School of Medicine\, University of Pennsylvania. He is currently the Chair of the Parkinson Study Group.Dr. Siderowf’s clinical practice focuses on the diagnosis and management of patients with Parkinson’s disease and related disorders. His research focuses on the design and conduct of clinical trials\, particularly the use of biomarkers as outcome measures.\r\n\r\nJoin the seminar via Zoom\nhttps://ki-se.zoom.us/j/67408275223?pwd=SUpySGxWMFhabkNHK2JETmJDQSs3dz09\r\n\r\nHot-topics in multimodal imaging"\; is a seminar series hosted by the Division of Imaging Core Facilities with a focus on multimodal imaging\, which will cover the latest research in the fields Neurology\, Psychiatry and Cognitive Neuroscience and will give our audience an overview of the state-of-the-art instruments\, computational and AI assisted data analysis being applied in the field by top international researchers.See our seminar calendar here and join us on Zoom. Welcome!\r\n\r\nPlease note that location\, time and information can be updated on the website.\r\nhttps://news.ki.se/calendar/synuclein-based-biomarkers-what-they-do-and-do-not-tell-us CREATED:20260810T083450Z LAST-MODIFIED:20260810T083450Z STATUS:CONFIRMED SUMMARY:Synuclein-based biomarkers: What they do and do not tell us END:VEVENT END:VCALENDAR