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PRODID:-//ki.se//NONSGML Event Calendar//EN
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BEGIN:VEVENT
DTSTART:20250922T110000Z
DTEND:20250922T120000Z
DTSTAMP:20250918T163057Z
UID:234532
DESCRIPTION:Welcome to a seminar with Zbynek Bozdech\, School of Biological Sciences\, Nanyang Technological University\, Singapore.\r\n\r\nTitle&quot\;Deciphering Modes of Action of Antimalarial Drugs by Thermal Protein&amp\;nbsp\;Profiling&quot\;SpeakerZbynek Bozdech\, School of Biological Sciences\, Nanyang Technological University\, SingaporeSelected Publications1. Samuel Pazicky\, Seth Tjia\, Guilherme B. Farias\, Nisha Philip\, Radoslaw M. Sobota\, Andrew P. Waters\, Tim-Wolf Gilberger\, Zbynek&amp\;nbsp\;Bozdech\, Thermal&amp\;nbsp\;profiling maps the dynamic interactome in malaria parasites.&amp\;nbsp\;https://doi.org/10.21203/rs.3.rs-5659511/v1&amp\;nbsp\;This is a preprint just accepted by Nature Microbiology&amp\;nbsp\;for publication.2. Go\, K. D.\, Yan\, X. F.\, Wirjanata\, G.\, Ero\, R.\, Pazicky\, S.\, Dziekan\, J.\, Tjia\, S.\, Lescar\, J.\, Bozdech\, Z.&amp\;nbsp\;&amp\;amp\; Gao\, Y. G.&amp\;nbsp\;Antimalarial drug artemisinin stabilizes PfRACK1 binding to the ribosome. Structure&amp\;nbsp\;33\, 1386-1397 e1385\, doi:10.1016/j.str.2025.05.008 (2025).3. Wirjanata\, G.\, Lin\, J.\, Dziekan\, J. M.\, El Sahili\, A.\, Chung\, Z.\, Tjia\, S.\, Binte Zulkifli\, N. E.\, Boentoro\, J.\, Tham\, R.\, Jia\, L. S.\, Go\, K. D.\, Yu\, H.\, Partridge\, A.\, Olsen\, D.\, Prabhu\, N.\, Sobota\, R. M.\, Nordlund\, P.\, Lescar\, J. &amp\;amp\; Bozdech\, Z.&amp\;nbsp\;Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development. Cell Chem Biol&amp\;nbsp\;31\, 743-759 e748\, doi:10.1016/j.chembiol.2024.03.002 (2024).4. Dziekan\, J. M.\, Wirjanata\, G.\, Dai\, L.\, Go\, K. D.\, Yu\, H.\, Lim\, Y. T.\, Chen\, L.\, Wang\, L. C.\, Puspita\, B.\, Prabhu\, N.\, Sobota\, R. M.\, Nordlund\, P. &amp\;amp\; Bozdech\, Z. Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome. Nat Protoc&amp\;nbsp\;15\, 1881-1921\, doi:10.1038/s41596-020-0310-z (2020).5. Dziekan\, J. M.\, Yu\, H.\, Chen\, D.\, Dai\, L.\, Wirjanata\, G.\, Larsson\, A.\, Prabhu\, N.\, Sobota\, R. M.\, Bozdech\, Z.&amp\;nbsp\;&amp\;amp\; Nordlund\, P. Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay. Sci Transl Med&amp\;nbsp\;11\, doi:10.1126/scitranslmed.aau3174 (2019).HostGerald McInerney\, Department of Microbiology\, Tumor and Cell Biology\, Karolinska Institutet\r\n\r\nPlease note that location\, time and information can be updated on the website.\r\nhttps://news.ki.se/calendar/infection-and-immunology-seminar-deciphering-modes-of-action-of-antimalarial-drugs-by-thermal-protein-profiling
CREATED:20250915T152923Z
LAST-MODIFIED:20250915T153515Z
STATUS:CONFIRMED
SUMMARY:Infection and Immunology Seminar: "Deciphering modes of action of antimalarial drugs by thermal protein profiling" 
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BEGIN:VEVENT
DTSTART:20251006T110000Z
DTEND:20251006T120000Z
DTSTAMP:20250918T163057Z
UID:234559
DESCRIPTION:Welcome to a seminar with Gunnar Nilsson\, Department of Medicine\, KI.\r\n\r\nTitle&quot\;Human Lung Mast Cell Diversity and Their Proinflammatory Response to IL-33&quot\;SpeakerGunnar Nilsson\, Department of Medicine\, KIHostItziar Martinez Gonzalez\, Department of Microbiology\, Tumor and Cell Biology\, Karolinska Institutet\r\n\r\nPlease note that location\, time and information can be updated on the website.\r\nhttps://news.ki.se/calendar/infection-and-immunology-seminar-human-lung-mast-cell-diversity-and-their-proinflammatory-response-to-il-33
CREATED:20250916T105512Z
LAST-MODIFIED:20250916T110003Z
STATUS:CONFIRMED
SUMMARY:Infection and Immunology Seminar: "'Human lung mast cell diversity and their proinflammatory response to IL-33"
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