Event type
Dissertations
Doctoral thesis defence: Yitian Zhou

26-11-2021 1:30 pm Add to iCal
Campus Solna
Location
Samuelssonsalen, Tomtebodavägen 6, Karolinska Institutet, Solna
Lead

Assessing the importance of rare genetic variants for drug response

Content

Title

"Assessing the importance of rare genetic variants for drug response"


Supervisor

Volker Lauschke, Researcher, Department of Physiology and Pharmacology


Co-supervisor

Magnus Ingelman- Sundberg, Professor, Department of Physiology and Pharmacology

Abstract

Read the Abstract here

Contact

Event type
Dissertations
Doctoral thesis defence: Erik von Oelreich

19-11-2021 9:00 am Add to iCal
Campus Solna
Location
Torsten Gordh Auditorium, S2:02, Norrbacka, Karolinska University Hospital, Solna
Lead

Long-term outcomes after trauma and intensive care

Content

Title

"Long-term outcomes after trauma and intensive care"

Author

Erik von Oelreich, Department of Physiology and Pharmacology

Supervisor

Anders Oldner, adjunct professor, Department of Physiology and Pharmacology

Co-supervisor

Emma Larsson, Department of Physiology and Pharmacology

Mikael Eriksson, Department of Physiology and Pharmacology

Abstract

Read the Abstract here

Contact

Published: 2021-10-25 15:26 | Updated: 2021-10-25 15:26

Ina Schuppe Koistinen recieves research grant from the Swedish Foundation for Strategic Research

Ina Schuppe Koistinen has received a research grant from SSF, for a project that aims to determine how the composition of the vaginal microbiome differs in healthy women from women diagnosed with bacterial vaginosis and candida infections.

Ina Schuppe Koistinen
Ina Schuppe Koistinen Photo: N/A

Congratulations Ina!

Can you tell us about the research grant you received?

I received a research grant from the Swedish Foundation for Strategic Research, SSF, as part of the SSF Industry Doctoral Student program. The grant covers the costs for a PhD student shared with an industrial partner to stimulate need-driven research in SSF’s areas of science, technology and medicine.

Tell us about your project.

We are only beginning to understand how the vaginal microbiome is intimately linked to women’s health. In this PhD-project, advanced sequencing techniques coupled with computational pipelines, machine learning techniques and mathematical modelling will be used to determine the microbial etiology of bacterial vaginosis and factors associated with an antibiotic-free treatment under development at our partner company Gedea Biotech.

The project aims to determine how the composition of the vaginal microbiome differs in healthy women from women diagnosed with bacterial vaginosis and candida infections. Furthermore, the impact of antibiotic and antibiotic-free treatments on the vaginal microbiome and risk of recurrence will be studied. In the process of understanding the microbial mechanisms involved in the success of this product, we will also develop deeper understanding of dynamics of recurrence and train a professional ready to bridge the gap between basic science and industrial applications in women’s health and microbiome sciences. 

Who is taking part in the study?

We partner up with Gedea Biotech, a small company in Lund that develops an antibiotic-free treatment of bacterial vaginosis and vulvovaginal candidiasis. Helena Strevens, senior consultant in obstetrics and gynecology at Skåne University Hospital and medical officer at Gedea is our co-applicant. At the Centre for Translational Microbiome Research (CTMR) Gabriella Edfeldt and Luisa Hugerth will be co-supervising the student with me.

Which patient groups will benefit from the research and how?

Bacterial vaginosis is a common and recurring vaginal infection with a disturbed vaginal microbiome among women of reproductive age. It is associated with adverse health outcomes, such as susceptibility to sexually transmitted infections, reduced fertility, pre-term birth, HPV infection and gynaecological cancers.

Recommended first-line treatments for BV are antibiotics with high initial cure rates but up to 50% of patients experience recurrence of BV within one year leading to repeated treatment with antibiotics adding to the global issue of antibiotic resistance. Only through carefully considering the impact of interventions on the vaginal microbiome, can we better treat common diseases like bacterial vaginosis and improve women’s health and fertility.

 

Contact

Event type
Internal courses and training
Liquid nitrogen safety course - additional date

26-10-2021 9:00 am Add to iCal
Location
Biomedicum room D1012
Lead

The Liquid Nitrogen Safety Course is mandatory for those who need access to the rooms with cryo-freezers in Biomedicum.
There will be an extra date for the course on Tuesday October 26th

Content

Registration

 

Register here

<a href="https://staff.ki.se/people/katrin-putsep">Katrin Pütsep</a>

  • Title: Researcher
  • Phone: +46-(0)8-524 871 13
  • Unit: C3 Department of Physiology and Pharmacology
  • Email: katrin.putsep@ki.se
catalogue Off Off Off Off

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Event type
Dissertations
Dissertation: Carl-Fredrik Bowin

12-11-2021 9:00 am Add to iCal
Campus Solna
Location
Eva & Georg Klein, Biomedicum, Solnavägen 9, Karolinska Institutet, Solna
Lead

Welcome to Carl-Fredrik Bowin's doctoral thesis defence with the title "RWNT/Frizzled signaling : illuminating the road towards pathway selectivity".

Content

Doctoral Student

Carl-Fredrik Bowin

Title

"RWNT/Frizzled signaling : illuminating the road towards pathway selectivity"

Supervisor

Professor Gunnar Schulte, Department of Physiology and Pharmacology, Karolinska Institutet

Abstract

Read it here

Contact

Event type
Lectures and seminars
Infection and Immunology Seminar with Jonas Klingström, MedH: "Hantaviruses and the diseases they cause - Who is killing who, how, and what are the consequences?"

01-11-2021 1:00 pm Add to iCal
Campus Solna
Location
Solna, room D1012 and online
Lead

Welcome to the Infection and Immunology Seminar with Jonas Klingström, MedH. Monday the 1st of November, 2021 at 1 pm.
The seminar is also available online.

Content

Titel

"Hantaviruses and the diseases they cause - Who is killing who, how, and what are the consequences?"

Speaker

 Jonas Klingström, MedH, Karolinska Institutet

Host

Jonathan Coquet, MTC, Karolinska Institutet

Location

Campus Solna, D1012 and online. Please contact the Host for the link.

Contact

Event type
Internal courses and training
Biomedicum courses in work environment: Course in laboratory safety - Basic

29-10-2021 10:00 am - 11:30 am Add to iCal
Online
Location
Zoom
Lead

You will learn practical and basic things regarding safety in the laboratory in Biomedicum. You will receive information about what services are offered for lab work in the house and what to do if you need help. You will receive information on how to handle chemicals in the lab, what risk assessments should be made, what protective equipment should be used and how to work with biosafety. Information regarding incidents and crises will be provided.

Content

The course is intended for everyone who is new to Biomedicum, but it is also good for you who feel insecure about safety routines in the lab. The course can also be good for you who have been in the lab longer and want to refresh your knowledge of lab safety. 

Register here  

When you have registered you will receive zoom link to the course.

<a href="https://staff.ki.se/people/jona-gudjonsdottir">Jona Gudjonsdottir</a>

  • Title: Coordinator
  • Phone:
  • Unit: C3 Department of Physiology and Pharmacology
  • Email: jona.gudjonsdottir@ki.se
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Contact

Event type
Internal courses and training
Biomedicum courses in work environment: Risk assessment for work with chemicals

28-10-2021 1:00 pm - 2:30 pm Add to iCal
Online
Location
Zoom
Lead

You will learn practical things regarding risk assessments, legal requirements, and tips on how to be successful in your risk assessment work.
You will also learn how to use KLARA for risk assessments.

Content

Registration

Register here

There is a limited number of places (25). 

When you have registered you will receive zoom link to the course.

<a href="https://staff.ki.se/people/jona-gudjonsdottir">Jona Gudjonsdottir</a>

  • Title: Coordinator
  • Phone:
  • Unit: C3 Department of Physiology and Pharmacology
  • Email: jona.gudjonsdottir@ki.se
catalogue Off Off Off Off

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Event type
Internal courses and training
Biomedicum courses in work environment: Waste handling

08-11-2021 1:00 pm - 2:30 pm Add to iCal
Online
Location
Zoom
Lead

You will learn about KIs waste handling routines as well as the specific routines that applies to Biomedicum.
Both recycling of non-harmful material and handling of laboratory waste will be brought up.

Content

Registration
 

Register here 

When you have registered you will receive zoom link to the course. 

<a href="https://staff.ki.se/people/jona-gudjonsdottir">Jona Gudjonsdottir</a>

  • Title: Coordinator
  • Phone:
  • Unit: C3 Department of Physiology and Pharmacology
  • Email: jona.gudjonsdottir@ki.se
catalogue Off Off Off Off

Contact

Event type
Lectures and seminars
Infection and Immunology Seminar with Marika Nestor, Uppsala University: "Cancer-targeting strategies for improved molecular radiotherapy"

08-11-2021 1:00 pm Add to iCal
Campus Solna
Location
Solna, room D1012 and online
Lead

Welcome to the Infection and Immunology Seminar with Marika Nestor. Monday the 8th of November, 2021 at 1 pm.
The seminar is also available online.

Content

Title

"Cancer-targeting strategies for improved molecular radiotherapy"

Speaker

Marika Nestor, Uppsala University

Host

Lisa Westerberg, Department of microbiology, tumor- and cell biology, Karolinska institutet

Location

Solna, room D1012, and online. Please contact the Host for the link.

Contact

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