https://ki.se RSS News Listing https://news.ki.se/thesis-on-survival-extrapolation-and-its-application-on-health-technology-assessment A new thesis from Karolinska Institutet focuses on advanced statistical methods to better predict long-term patient outcomes, supporting healthcare decision-making. The application focused on chronic myeloid leukemia with the goal to inform clinical and policy insights. Wed, 03 Sep 2025 10:59:17 +0200 https://news.ki.se/apply-for-grants-from-sfoepi-autumn-2025 The Strategic Research Program in epidemiology (SFOepi) at Karolinska Institutet now announces funding for two types of grants; Consolidator Grant for junior researchers, Junior Scholar Grants in Epidemiology or Biostatistics. Fri, 22 Aug 2025 14:39:03 +0200 https://news.ki.se/clinicum-is-the-coffee-room-of-ki Thomas Frisell is a Principal researcher and docent in epidemiology at the Department of Medicine, Solna, and coordinates health data counseling in Clinicum. As a method-oriented epidemiologist, he is particularly focused on study design, biostatistics and how we can best use registries and other health data sources for clinical and epidemiological research. Mon, 02 Jun 2025 13:46:30 +0200 https://news.ki.se/by-using-qualitative-methods-researchers-can-gain-a-richer-and-more-nuanced-understanding Anna Schandl is a registered nurse and has worked in intensive care in the Stockholm Region for many years. She is an associate professor in nursing and research group leader in the research group for Perioperative Care and Intensive Care at Södersjukhuset. Anna works with data collected from regional and national cohort studies, but also with qualitative research; something she uses as an advisor within Clinicum's network. Mon, 31 Mar 2025 14:31:09 +0200 https://news.ki.se/msca-postdoctoral-fellowship-to-caterina-gregorio Caterina Gregorio has received funding in the context of Marie Sklodowska-Curie Actions (MSCA) Postdoctoral Fellowship within the area of intersecting biostatistics and ageing research for her project entitled "LETMEAGE- A complex system approach to metrics of aging for identifying personalised interventions”. Wed, 19 Feb 2025 11:08:37 +0100 https://news.ki.se/cecilia-lundholm-helps-researchers-find-the-right-methodology-expert Cecilia Lundholm is the coordinator of Clinicum's advisory network, the network of methodology experts who help researchers with methodological issues. Cecilia is also an advisor in the network, in biostatistics and epidemiology with a special focus on reproductive epidemiology and pediatric epidemiology. In addition, she is the head of the department's applied biostatistics group. Fri, 31 Jan 2025 16:00:09 +0100 https://news.ki.se/clinicum-offer-programming-support-without-hassle-and-prestige Daniel Sjöholm is one of many experts in Clinicum's network, supporting researchers who need help with various methodological issues. Daniel is a research engineer at the Department of Medicine in Solna, and a specialist in programming. He can help you understand what you want and can do with data - something that is very useful in his role as one of Clinicum's advisors. Mon, 13 Jan 2025 16:00:11 +0100 https://news.ki.se/meb-receives-120-millions-in-swedish-grants Congratulations to the researchers at the Department of Medical Epidemiology and Biostatistics (MEB) who received a total of nearly 120 million SEK from the Swedish funding agencies (FORTE, the Swedish Research Council, the Swedish Cancer Society and the Erling-Persson Foundation)! Thu, 05 Dec 2024 08:58:05 +0100 https://news.ki.se/multiple-time-scales-with-flexible-parametric-survival-models A new thesis from Karolinska Institutet shows the effectiveness of flexible parametric survival models in modelling multiple time-scales, providing a robust tool for complex time-to-event data analysis. The models were tested in the context of myeloproliferative neoplasms, a group of chronic hematologic malignancies in which the bone marrow makes too many red blood cells, white blood cells, or platelets. Mon, 25 Nov 2024 16:52:44 +0100 https://news.ki.se/weighty-matters-disentangling-the-body-mass-index-metabolic-health-and-aging-connection-0 As global populations age and the prevalence of obesity and metabolic disorders rises, understanding the complex relationships between body mass index (BMI), metabolic health, and aging becomes increasingly critical. Fri, 08 Nov 2024 09:23:16 +0100 https://news.ki.se/sharpen-your-research-with-clinicums-methodological-support In Clinicum's network there are advisers with many different backgrounds who contribute with their experience - all to enhance your research. We have talked to one of them, Stephen Nash, a statistician at MEB, and asked some questions about what to consider when submitting an application to Clinicum. Mon, 28 Oct 2024 09:46:21 +0100 https://news.ki.se/statistical-and-computational-methods-for-analyzing-omics-data-and-predicting-drug-responses Recent advancements in high-throughput sequencing technologies have enabled researchers to harness valuable omics data, paving the way for precision medicine. This approach aims to enhance diagnosis and treatment by tailoring therapies to individual patients, moving away from traditional, subjective methods. However, analyzing omics data for effective treatment personalization remains challenging due to disease variability and data complexity. Tue, 22 Oct 2024 11:33:26 +0200 https://news.ki.se/helping-medical-scientists-analyse-causal-relationships Arvid Sjölander works with statistical tools and mathematical models to help medical scientists make more reliable estimations of causal effects. Meet one of the new professors of Karolinska Institutet who will participate in this year's installation ceremony at Aula Medica on 3 October. Tue, 03 Sep 2024 09:00:12 +0200 https://news.ki.se/new-evaluation-of-clinicums-advisory-support-shows-satisfied-researchers In the spring of 2024, an invitation was sent to researchers to participate in an evaluation of Clinicum's method support. Of all those who used the support, 7/10 were very satisfied and 9/10 would recommend it to a colleague. Some of the reasons for the satisfaction were that many people refer to a high level of competence and pedagogical ability of the methodological advisers, as well as the possibility of getting help quickly. Helpfulness, friendliness, and flexibility are also highlighted. Wed, 28 Aug 2024 15:33:46 +0200 https://news.ki.se/key-insights-from-statistical-modelling-of-cancer-patient-life-expectancy With the progress in treatment for most cancer types, there is a growing interest to understand the overall impact of a cancer diagnosis throughout the remaining lifespan. In addition to conventional survival probabilities, estimating Life Expectancy following cancer diagnosis and Loss in Life Expectancy for cancer patients in comparison to if they did not have cancer provides valuable insights into the societal burden of cancer. Wed, 03 Apr 2024 09:09:56 +0200 https://news.ki.se/paul-dickman-awarded-prize-as-the-statistical-promoter-of-the-year-2023 Professor Paul Dickman at the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet is awarded the prize Statistical Promotor of the year from the Swedish Statistical Society (Svenska statistikfrämjandet). Thu, 21 Mar 2024 08:23:02 +0100 https://news.ki.se/successful-method-support-day-for-researchers-at-ki-and-region-stockholm On January 25, a method support day was organized by Clinicum to introduce researchers to the coordinated method support offered to researchers at KI and Region Stockholm. The meeting was held in the Sune Bergström Hall at Karolinska University Hospital. Wed, 31 Jan 2024 13:29:22 +0100 https://news.ki.se/johan-hartman-and-mattias-rantalainen-awarded-the-2023-prize-for-innovation-and-utilization Karolinska Institutet has decided to award Johan Hartman and Mattias Rantalainen the 2023 Prize for Innovation and Utilization. They are rewarded for improving cancer diagnostics with innovative research and inspiring working methods. Thu, 11 May 2023 09:10:43 +0200 https://news.ki.se/apply-for-grants-from-sfoepi-2023 The Strategic Research Program in epidemiology (SFOepi) at Karolinska Institutet now announces funding for three different types of grants; Consolidator Grant for junior researchers, Junior Scholar Grants in Epidemiology or Biostatistics and small grants. Tue, 09 May 2023 15:49:54 +0200 https://news.ki.se/prediction-driven-decision-rules-randomized-control-study-design-and-survival-analysis Predictions are becoming more and more a part of our lives, and they are becoming increasingly useful in medical science as the science evolves. Increased understanding of disease and its treatments allows us to use predictions based on predictive biomarker signatures to optimize treatment outcomes for increasingly specific subject groups. Thu, 13 Apr 2023 09:20:16 +0200 https://news.ki.se/method-development-for-analyzing-omics-data-to-study-complex-diseases In a new thesis from Karolinska Institutet, the focus was on the use of multiomics data in the discovery of disease signatures. Fri, 24 Mar 2023 14:02:04 +0100 https://news.ki.se/development-and-application-of-statistical-models-in-cancer-epidemiology Competing risks and multi-state models allow us to study complex disease settings and answer composite research questions and should be used more widely in epidemiology. Wed, 08 Mar 2023 15:19:16 +0100 https://news.ki.se/advanced-course-in-network-medicine From byte to bench to bed side – addressing large and complex data sets in biomedicine KI Network Medicine Alliance offers an advanced course in Network Medicine 19th-20th of October 2022 Mon, 26 Sep 2022 16:58:12 +0200 https://news.ki.se/machine-learning-methods-for-precision-medicine In precision medicine, predicting the risk of an event during a specific period may help, for example, to identify patients that need early preventive treatment. Modern machine learning (ML) techniques are therefore ideal for building these predictions. Fri, 01 Jul 2022 14:10:18 +0200 https://news.ki.se/cbb-network-event-october-7th-12-pm-to-6-pm Centre for Bioinformatics and Biostatistics arranges a networking event for researchers within bioinformatics and biostatistics Friday October 7th from 12 pm to 6 pm. The event takes place right after the conference Collaboration in Science 2022 and will be held in Neo building at Campus Flemingsberg. Register before September 9th! Wed, 29 Jun 2022 14:38:31 +0200 https://news.ki.se/recruitment-assistance-within-bioinformatics-and-biostatistics Are you interested in recruiting a bioinformatician or biostatistician? The centre for bioinformatics and biostatistics (CBB) is coordinating recruitments with possibility to make joint employments. Fri, 19 Nov 2021 08:28:41 +0100 https://news.ki.se/enoch-yi-tung-chen-awarded-prize-for-best-student-paper-in-medical-statistics-from-the-swedish-society-for-medical-statistics Enoch Yi-Tung Chen has been awarded the Swedish Society for Medical Statistics (Föreningen för Medicinsk Statistik, FMS) prize for best student project in the area of medical statistics during 2020. The prize, which includes an award of 5000 SEK, was announced at the FMS annual general meeting on 25 March 2021. Thu, 25 Mar 2021 13:16:47 +0100 https://news.ki.se/karolinska-institutet-and-karolinska-university-hospital-establish-new-centre-for-bioinformatics-and-biostatistics-at-campus-flemingsberg Today's research is generating more and more big data, which means that the demand for bioinformatics and biostatistics is growing. Karolinska Institutet and Karolinska University Hospital are therefore establishing a new centre at Campus Flemingsberg that will offer expertise and networking opportunities for the preclinical and clinical research environment in the area. Mon, 15 Mar 2021 09:00:03 +0100 https://news.ki.se/chlamydia-trachomatis-infection-in-sweden-new-thesis-sheds-light-on-time-trends-prevalence-and-risk-factors Chlamydia trachomatis infection is the most common bacterial sexually transmitted infection (STI), with about 127 million new cases estimated annually worldwide. Since it is an asymptomatic infection, individuals may carry it for a long time and unknowingly transmit the infection to others. Mon, 22 Feb 2021 11:53:15 +0100 https://news.ki.se/president-of-national-health-research-institutes-of-taiwan-speaks-about-importance-of-biostatistics Dr Kung-Lee Liang, a pioneer in the field of biostatistics, gave a webinar via zoom with more than 100 attendees, including the President of KI, Ole Petter Ottersen. Dr. Liang spoke about how biostatistics contributed to medical science in the 20th century, and how we can rise to meet the current and future challenges in public health. Mon, 01 Feb 2021 16:22:23 +0100 https://news.ki.se/adaptation-of-the-charlson-comorbidity-index-cci-for-register-based-research-in-sweden The Charlson co-morbidity index (CCI) is a disease index that was originally created to predict short-term mortality but is increasingly used as a proxy for comorbidity burden, and is often used as a co-variate, for instance in regression models. There are currently several available versions of the CCI. The existence of multiple morbidity indices creates confusion, increases the risk of mistakes and requires individual researchers to spend considerable time examining included codes. Thu, 14 Jan 2021 12:56:33 +0100 https://news.ki.se/risk-assessment-and-prevention-of-breast-cancer One woman in eight develops breast cancer during her lifetime in the Western world and although mammography screening reduces mortality by early detection, approximately one fourth of the women who develop breast cancer are diagnosed within two years after a negative screen. Fri, 08 Jan 2021 09:23:26 +0100 https://news.ki.se/insights-into-nasopharyngeal-carcinoma-risks-and-prognosis Nasopharyngeal carcinoma (NPC), or nasopharynx cancer, is a malignant disease characterized by unique geographic distribution endemic to southern China, Southeast Asia, and the Middle East/North Africa. It is known that the interaction of Epstein-Barr Virus infection, environmental and lifestyle factors, and genetic susceptibility, contributes to NPC carcinogenesis. Mon, 30 Nov 2020 13:17:10 +0100 https://news.ki.se/attention-deficithyperactivity-disorder-and-adverse-health-outcomes Shihua Sun has investigated the associations between attention-deficit/hyperactivity disorder (ADHD) and specific adverse outcomes including asthma and premature death. In his thesis, Shihua included four studies to clarify the magnitude and etiology of the associations, as well as potential effects from medication treatment that may prevent poor prognosis. Fri, 27 Nov 2020 16:37:37 +0100 https://news.ki.se/breast-cancer-risk-determinants-and-influence-of-mammographic-features In her thesis, Shadi Azam studied the association between established breast cancer risk factors with mammographic density change over time and mammographic microcalcifications by using data from the prospective KARMA cohort. Fri, 20 Nov 2020 13:36:37 +0100 https://news.ki.se/statistical-tools-for-valid-causal-inference-with-fewer-assumptions Causal inference is important in medical research to help determine if treatments are beneficial and if natural exposures are harmful. In many settings, data collection makes causal inference difficult without making overly optimistic or idealistic assumptions. In a new article published in the Journal of the American Statistical Association, researchers at Karolinska Institutet develop new statistical methods to make causal inference possible in some settings without making such assumptions. Thu, 15 Oct 2020 16:10:52 +0200 https://news.ki.se/molecular-epidemiology-studies-on-risk-factors-and-aggressive-breast-cancer In his thesis, Emilio Ugalde Morales uses a molecular epidemiology approach to investigate the association between risk factors and aggressive breast cancer defined by tumor characteristics, intrinsic subtypes, mode of detection, and survival. Wed, 16 Sep 2020 09:05:06 +0200 https://news.ki.se/novel-statistical-methods-for-genome-wide-association-summary-statistics At the moment we live in an era where it is easier to generate data than to interpret them. The focus of Zheng Ning’s thesis is on methodology and analysis to exploit novel biological knowledge from published results of genome-wide association study (GWAS). Fri, 28 Aug 2020 11:25:33 +0200 https://news.ki.se/publication-in-nature-genetics-high-definition-likelihood-inference-of-genetic-correlations-across-human-complex-traits Evaluating the genetic correlations across our phenotypes is of essential importance for understanding disease etiology and other potential causality. The new method – published in the journal Nature Genetics – vastly improves our power in estimating genetic correlations using the huge established resources from genome-wide association studies. Wed, 01 Jul 2020 16:06:52 +0200 https://news.ki.se/etiology-and-prognosis-of-gastric-and-esophageal-cancer-explored The focus of Isabella Ekheden's thesis is on gastric and esophageal cancer – gastroesophageal cancers - that are some of the most fatal malignancies in the world. Understanding the cause of these diseases is key to interventions such as primary prevention and/or surveillance with the potential of lowering the disease burden. Fri, 29 May 2020 15:53:21 +0200 https://news.ki.se/personality-stress-and-risk-of-parkinsons-disease The focus of Johanna Sieurin's thesis was to investigate the relationship of personality and stress with subsequent risk of Parkinson’s disease (PD). Tue, 12 May 2020 11:40:38 +0200 https://news.ki.se/new-measure-of-broad-psychopathology-can-predict-future-care-requirement Researchers at Karolinska Institutet show that different measures of psychopathology can be combined into a single factor, “p”, which predicts the patient’s prognosis and need of extra support. The general factor of psychopathology reflects the overall risk of adverse psychiatric outcomes with an accuracy equal to that currently used for intelligence, they report in a paper published in World Psychiatry. Tue, 12 May 2020 08:49:27 +0200 https://news.ki.se/artificial-intelligence-for-streamlining-prostate-cancer-diagnostics The objective of Peter's thesis is to develop and improve technologies for prostate cancer diagnostics and to acquire knowledge related to these technologies that directly translate to clinical utility. Mon, 27 Apr 2020 13:09:26 +0200 https://news.ki.se/socioeconomic-inequalities-and-cardiovascular-disease-in-sweden In her thesis, Ninoa Malki concludes that socioeconomic differences are associated with both incidence and mortality of cardiovascular disease in Sweden. Mon, 02 Mar 2020 16:45:32 +0100 https://news.ki.se/thesis-on-association-between-neuroinflammation-and-als-and-ms On Friday December 18, Elisa Longinetti will defend her thesis "Amyotrophic lateral sclerosis and multiple sclerosis associated neuroinflammation: nationwide epidemiological studies on etiology, comorbidities, and treatment" Tue, 03 Dec 2019 15:59:44 +0100 https://news.ki.se/thesis-on-sex-differences-in-cancer-risk-and-survival On Friday December 6, 2019 Cecilia Radkiewicz defended her thesis "Sex differences in cancer risk and survival". Wed, 20 Nov 2019 15:24:54 +0100 https://news.ki.se/thesis-on-statistical-models-of-breast-cancer-tumour-growth-and-spread On Tuesday December 10, Gabriel Isheden will defend his thesis Statistical models of breast cancer tumour growth and spread". Mon, 18 Nov 2019 11:07:38 +0100 https://news.ki.se/low-iq-family-history-tied-to-treatment-resistant-schizophrenia Those with a family history of schizophrenia and men with lower IQ are more likely to struggle with treatment resistant schizophrenia than others with the mental disorder, according to a study by researchers at Karolinska Institutet in Sweden published in the journal Molecular Psychiatry. The researchers say the findings could be important in efforts to design novel drug treatments that improve cognition. Tue, 12 Nov 2019 02:00:00 +0100 https://news.ki.se/thesis-on-the-comorbidity-between-adhd-disorder-and-other-neurodevelopmental-disorders-aetiology-treatment-and-outcomes Title: The comorbidity between attention-deficit/hyperactivity disorder and other neurodevelopmental disorders: aetiology, treatment and outcomes Wed, 25 Sep 2019 11:07:38 +0200 https://news.ki.se/thesis-on-risk-prediction-in-prostate-cancer-diagnostics Title: Risk prediction in prostate cancer diagnostics : current challenges and improvements Mon, 16 Sep 2019 10:36:46 +0200 https://news.ki.se/thesis-on-socioeconomic-influences-on-late-life-health-and-mortality Title: Socioeconomic influences on late-life health and mortality : exploring genetic and environmental interplay  Mon, 16 Sep 2019 10:36:46 +0200 https://news.ki.se/meb-biostatisticians-awarded-research-environment-grant-for-research-in-statistical-methods-for-register-based-research A group of biostatistical scientists at the Department of Medical Epidemiology and Biostatistics (MEB) have been awarded a research environment grant of SEK 13 million from the Swedish Research Council for research into the development and application of statistical methods for register-based research. Fri, 13 Sep 2019 11:44:44 +0200 https://news.ki.se/new-head-of-department-for-meb Mon, 03 Dec 2018 10:39:24 +0100 https://news.ki.se/potential-effects-of-fertility-treatments-on-breast-density-and-cancer-risk Wed, 13 Apr 2016 10:02:21 +0200 https://news.ki.se/51-million-sek-to-13-researchers-at-the-department Wed, 04 Nov 2015 17:03:26 +0100