https://ki.se RSS News Listing https://news.ki.se/progress-in-stem-cell-therapy-for-type-1-diabetes Researchers at Karolinska Institutet and KTH Royal Institute of Technology have developed an improved method for creating insulin-producing cells from human stem cells. The results, published in Stem Cell Reports, demonstrate that these cells effectively regulate blood sugar levels in laboratory tests and can reverse diabetes in mice. Thu, 16 Apr 2026 17:00:08 +0200 https://news.ki.se/children-with-obesity-are-at-risk-of-illness-despite-normal-test-results Children living with obesity but showing no signs of metabolic complications still have a significantly increased risk of developing type 2 diabetes, high blood pressure, and abnormal blood lipid levels later in life. A new study from the Karolinska Institutet, published in JAMA Pediatrics, also shows that these children benefit greatly from obesity treatment. Mon, 23 Mar 2026 16:01:08 +0100 https://news.ki.se/diabetes-drug-ozempic-linked-to-better-mental-health GLP-1 receptor agonist drugs, commonly used to treat diabetes and obesity, are associated with a reduced need for hospital care and sickness absence due to mental ill-health in people with depression or anxiety. This is according to a large, register-based study published in The Lancet Psychiatry by researchers at Karolinska Institutet in Sweden, the University of Eastern Finland, and Griffith University in Australia. Thu, 19 Mar 2026 00:30:24 +0100 https://news.ki.se/insulin-resistance-before-stroke-may-affect-recovery-in-diabetes Treating insulin resistance before a stroke may be more important for recovery than lowering blood sugar. This is shown by a new study on mice from Karolinska Institutet, published in the journal Diabetes. The results suggest that low-grade inflammation may be a contributing factor. Wed, 18 Mar 2026 09:27:52 +0100 https://news.ki.se/mitochondrial-rna-may-contribute-to-improved-wound-healing-in-diabetes Researchers at Karolinska Institutet have identified a circular RNA in mitochondria that plays an important role in the healing of chronic wounds. The study is published in Advanced Science. Thu, 12 Feb 2026 14:14:24 +0100 https://news.ki.se/katarina-berinder-has-been-appointed-docent-in-endocrinology-and-diabetes Katarina Berinder at the Experimental and Clinical Neuroendocrinology research group, Department of Molecular Medicine and Surgery, became docent in endocrinology and diabetes on January 27, 2026. Katarina's research is primarily focused on pituitary diseases, with a particular focus on hyperprolactinemia. She conducts clinical and epidemiological studies in the pituitary area as well as other endocrine diseases, including adrenal diseases. Wed, 11 Feb 2026 12:15:25 +0100 https://news.ki.se/new-study-explains-the-link-between-long-term-diabetes-and-vascular-damage The longer a person has type 2 diabetes, the greater the risk of cardiovascular disease. A new study from Karolinska Institutet, published in the journal Diabetes, shows that changes in red blood cells may be an important explanation, and identifies a specific molecule as a possible biomarker. Fri, 09 Jan 2026 10:34:15 +0100 https://news.ki.se/complications-after-stent-surgery-more-common-in-individuals-with-diabetes Patients with diabetes have an increased risk of complications after stent implantation, according to a study from Karolinska Institutet published in Diabetes Care. The study, which includes over 160,000 patients, emphasises the importance of tailoring treatment strategies for this specific patient group. Thu, 27 Nov 2025 06:05:12 +0100 https://news.ki.se/new-method-provides-unique-insight-into-the-bodys-insulin-production Researchers at Karolinska Institutet have developed a new method for studying the body's insulin-producing cells in mice. By placing small parts of the pancreas in an unexpected place in the body, the researchers can follow the work of the cells in detail. The study, which has been published in Nature Communications, may eventually contribute to better treatments for diabetes. Tue, 18 Nov 2025 16:24:47 +0100 https://news.ki.se/3rd-nordic-obesity-meeting-in-stockholm-feb-2026 Registration is now open for the 3rd Nordic Obesity Meeting, NOM2026, held at Läkaresällskapet in Stockholm on February 5-6 2026 and also available to follow online! Mon, 17 Nov 2025 11:50:37 +0100 https://news.ki.se/sons-of-mothers-with-type-1-diabetes-show-early-signs-of-vascular-dysfunction A new study from Karolinska Institutet and Stockholm University reveals that sons born to mothers with type 1 diabetes may develop early vascular dysfunction – independently of metabolic health. The finding may help shape future strategies to prevent cardiovascular disease early in life. Tue, 11 Nov 2025 17:34:35 +0100 https://news.ki.se/ki-researcher-sergiu-catrina-receives-grant-from-the-us-for-a-diabetes-study Sergiu Catrina, associate professor of endocrinology at Karolinska Institutet and medical director at the Center for diabetes, has been awarded a three-year research grant of just over USD 1 million from the American organisation Breakthrough T1D. The grant funds a study investigating the effect of the drug roxadustat on kidney oxygenation in individuals with type 1 diabetes. Thu, 09 Oct 2025 13:39:26 +0200 https://news.ki.se/hunting-down-the-genetics-of-serious-liver-disease Fatty liver results from overweight and obesity and it is a common disease leading to cirrhosis and liver cancer. Stefano Romeo is investigating the genetic basis of the diseases to identify novel therapeutic strategies. Meet one of the new professors of Karolinska Institutet who will participate in this year's installation ceremony at Aula Medica on 9 October. Fri, 29 Aug 2025 10:00:14 +0200 https://news.ki.se/new-method-may-enable-early-prevention-of-type-1-diabetes Researchers at Karolinska Institutet, KTH Royal Institute of Technology and SciLifeLab have developed a new method for detecting early signs that the disease type 1 diabetes is going to develop. The study, conducted in an experimental model, shows that analysing tiny amounts of blood can reveal disease-causing changes in the body, thereby enabling early treatment and disease prevention. The results have been published in the journal Diabetologia. Mon, 25 Aug 2025 14:01:07 +0200 https://news.ki.se/newly-discovered-molecule-may-explain-reduced-muscle-mass-in-type-2-diabetes Researchers at Karolinska Institutet have discovered a previously unknown molecule that may explain why people with type 2 diabetes often suffer from muscle weakness and muscle loss – a condition that has a major impact on quality of life and overall health. Thu, 10 Jul 2025 09:07:56 +0200 https://news.ki.se/new-possibilities-for-engineering-safer-medications Shane Wright, Assistant Professor at the Department of Physiology and Pharmacology, and colleagues have uncovered a new way to tailor signaling responses mediated by common drug targets that coincidentally shares ties with our department’s history. The work, recently published in Cell, reveals a novel drug mechanism with the potential for treating type 2 diabetes and obesity. Shane tells us more about it below. Mon, 23 Jun 2025 17:28:03 +0200 https://news.ki.se/new-drug-for-diabetes-and-obesity-shows-promising-results Lower blood sugar and increased fat burning – without negatively affecting appetite or muscle mass. These are some of the most promising effects of a new potential drug treatment for people with type 2 diabetes and obesity, according to a new study published in the journal Cell by researchers from Karolinska Institutet and Stockholm University. Mon, 23 Jun 2025 17:06:27 +0200 https://news.ki.se/western-diet-can-cause-permanent-pancreatic-damage-new-study-finds Long-term Western diet impairs islet blood vessel function and insulin transport even after diet reversal and weight loss, according to a new study from researchers at Karolinska Institutet. Fri, 13 Jun 2025 10:48:29 +0200 https://news.ki.se/protein-from-bacteria-appears-to-slow-the-progression-of-alzheimers-disease A protein from the bacterium Helicobacter pylori has been shown to block the formation of harmful protein aggregates - known as amyloids - that are linked to Alzheimer's, Parkinson's and type 2 diabetes, among other diseases, and bacterial infections. This is the result of a new study published in the journal Science Advances. Thu, 12 Jun 2025 11:20:12 +0200 https://news.ki.se/novo-nordisk-foundation-grant-for-ki-researcher-in-type-2-diabetes Amir Ata Saei, assistant professor at the Department of Microbiology, Tumor and Cell Biology has been awarded the Novo Nordisk Foundation Excellence Emerging Investigator Grant within Endocrinology and Metabolism 2025. Fri, 23 May 2025 15:23:15 +0200 https://news.ki.se/adult-onset-type-1-diabetes-increases-risk-of-cardiovascular-disease-and-death A new study in the European Heart Journal shows that people who develop type 1 diabetes in adulthood have an increased risk of cardiovascular disease and death, and that those diagnosed later in life do not have a better prognosis than those diagnosed earlier. The study, conducted by researchers at Karolinska Institutet, points to smoking, poor glucose control and obesity as the main risk factors. Wed, 14 May 2025 09:00:14 +0200 https://news.ki.se/medh-researcher-awarded-the-camillo-golgi-prize Congratulations to Mikael Rydén, the first Swede to be awarded the Camillo Golgi Prize. Fri, 25 Apr 2025 14:57:43 +0200 https://news.ki.se/combined-screening-can-detect-liver-damage-in-diabetes-patients New research from Karolinska Institutet highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye disease. The study is published in Lancet Gastroenterology and Hepatology. Fri, 13 Dec 2024 00:30:10 +0100 https://news.ki.se/professor-malin-flodstrom-tullberg-awarded-the-johnny-ludvigsson-prize Professor Malin Flodström-Tullberg at Karolinska Institutet has been awarded this year’s Johnny Ludvigsson Prize for Outstanding Nordic Researcher. The prize recognizes her groundbreaking research on the mechanisms behind type 1 diabetes. Wed, 16 Oct 2024 14:45:36 +0200 https://news.ki.se/new-study-shows-how-muscle-energy-production-is-impaired-in-type-2-diabetes A new study from Karolinska Institutet, published in Science Translational Medicine, shows that people with type 2 diabetes have lower levels of the protein that breaks down and converts creatine in the muscles. This leads to impaired function of the mitochondria, the 'powerhouses' of the cell. Thu, 10 Oct 2024 10:10:45 +0200 https://news.ki.se/prize-for-study-showing-new-cause-behind-vascular-complications-in-type-2-diabetes The Swedish Society of Medicine (SLS) awards researchers John Pernow and Aida Collado Sánchez at Karolinska Institutet with the Alvarenga Prize 2024. The laureates are rewarded for a research article on a study that shows a new cause behind vascular complications in type 2 diabetes and possible future treatment to prevent this. Tue, 01 Oct 2024 11:11:29 +0200 https://news.ki.se/no-link-found-between-popular-diabetes-medication-and-suicide There has been concern that common diabetes drugs could increase the risk of suicide and self-harm. In a new study, led by researchers at Karolinska Institutet and published in Jama Internal Medicine, no such risk increase was observed. Wed, 04 Sep 2024 09:33:09 +0200 https://news.ki.se/a-healthy-lifestyle-may-counteract-diabetes-associated-brain-ageing Type 2 diabetes and prediabetes are associated with accelerated brain ageing, according to a new study from Karolinska Institutet published in the journal Diabetes Care. The good news is that this may be counteracted by a healthy lifestyle. Wed, 28 Aug 2024 13:00:13 +0200 https://news.ki.se/professor-juleen-zierath-receives-prestigious-award-for-diabetes-research Professor Juleen Zierath is this year's recipient of the prestigious Diabetes Prize for Excellence, awarded by the European Association for the Study of Diabetes (EASD) research network and the research foundation Novo Nordisk Foundation. Juleen Zierath receives the prize for her groundbreaking research on physical activity and diabetes. Thu, 22 Aug 2024 12:56:13 +0200 https://news.ki.se/popular-drug-linked-to-reduced-risk-of-dementia-in-older-diabetes-patients Older people with type 2 diabetes who are treated with GLP-1 agonists have a decreased risk of developing dementia, according to a new study from Karolinska Institutet published in the journal eClinicalMedicine. Fri, 21 Jun 2024 06:00:11 +0200 https://news.ki.se/new-thesis-about-latent-autoimmune-diabetes-in-adults-lada Welcome to Jessica Edstorp's defence of her doctoral thesis "Infections, antibiotics, tobacco, genetic factors and risk of LADA - latent autoimmune diabetes in adults, and type 2 diabetes" at Karolinska Institutet on 17 May. Wed, 08 May 2024 14:17:24 +0200 https://news.ki.se/new-drug-candidate-reverses-obesity-in-mice Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells’ powerhouses, the mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block mitochondrial function can reverse diet-induced obesity, fatty liver and diabetes in mice. Tue, 30 Apr 2024 11:00:12 +0200 https://news.ki.se/popular-diabetes-drugs-do-not-increase-thyroid-cancer-risk-study-suggests Drugs known as GLP-1 analogues have become increasingly popular to treat diabetes and obesity, but there have been concerns that they might increase the risk of thyroid cancer. Now an extensive Scandinavian study led by researchers at Karolinska Institutet has found no evidence of such a link. The study is published in The BMJ. Wed, 10 Apr 2024 08:30:11 +0200 https://news.ki.se/common-anti-diabetic-drugs-can-improve-the-outcome-after-stroke People with type 2 diabetes have an increased risk of stroke and a worsened outcome after suffering from it. Now, researchers at the Karolinska Institutet have shown that stroke outcome is significantly improved in mice with obesity and type 2 diabetes who have been treated with the commonly used diabetic drugs SGLT-2 inhibitors. The results are published in the scientific journal Cardiovascular Diabetology and may have clinical relevance for stroke rehabilitation in type 2 diabetes. Fri, 01 Mar 2024 11:04:59 +0100 https://news.ki.se/researchers-use-the-eye-as-a-window-to-study-liver-health Researchers at Karolinska Institutet have developed a method to study liver function and disease without requiring invasive procedures. After transplanting liver cells into the eye of mice, the cornea can be used as a window into the body to monitor liver health over time. The study is published in the journal Nature Communications. Thu, 01 Feb 2024 15:51:05 +0100 https://news.ki.se/erc-proof-of-concept-to-professor-per-olof-berggren Professor Per-Olof Berggren has been awarded a ERC Proof of Concept grant by the European Research Council (ERC). The funding will be used to advance a technology in which islets of Langerhans are transplanted into the anterior chamber of the eye and employed as a screening tool to identify novel pharmaceutical treatments for diabetes. Fri, 19 Jan 2024 18:05:10 +0100 https://news.ki.se/newer-diabetes-drugs-do-not-increase-fetal-risk Newer diabetes medicines do not appear to increase the risk of birth defects. The largest comparative study to date found no increased risk compared to treatment with insulin, which is considered safe during pregnancy. The study was published in JAMA Internal Medicine. Mon, 11 Dec 2023 17:03:15 +0100 https://news.ki.se/lisa-juntti-berggren-receives-the-swedish-society-of-medicines-jubilee-prize Professor Lisa Juntti-Berggren at Karolinska Institutet is awarded the Swedish Society of Medicine's Jubilee Prize 2023 for her studies on Apolipoprotein CIII and diabetes mellitus. The awardee is rewarded with SEK 150,000 and the SLS centenary medal in silver. Fri, 20 Oct 2023 11:41:09 +0200 https://news.ki.se/eye-implant-may-be-used-to-treat-diabetes Researchers at Karolinska Institutet and KTH Royal Institute of Technology have developed a microscale device for implantation in the eye, which presents new opportunities for cell-based treatment of diabetes and other diseases. The study is published in the journal Advanced Materials. Wed, 18 Oct 2023 15:28:38 +0200 https://news.ki.se/virginia-stone-receives-an-award-from-the-childhood-diabetes-foundation We congratulate Virginia Stone, who has been awarded the 2023 Johnny Ludvigsson Prize for Younger Childhood Diabetes Researchers in Sweden. Wed, 18 Oct 2023 15:11:51 +0200 https://news.ki.se/nanoclusters-of-insulin-can-control-insulin-activity A recently published study shows how nanoclusters of insulin can control insulin activity. The results can lead to new types of insulin drugs, senior author Ana Teixeira at the Department of Medical Biochemistry and Biophysics (MBB) at Karolinska Institutet, says. Mon, 09 Oct 2023 17:00:03 +0200 https://news.ki.se/grants-from-novo-nordisk-foundation-to-bionut-2023 We wish to congratulate Professor Eckardt Treuter, at the Department of Biosciences and Nutriton, Karolinska Institutet, who has received the Novo Nordisk Foundation Project Grant in Endocrinology & Metabolism 2023, for a project on "Role of monocyte enhancers and silencers in inflammatory type 2 diabetes" (2 years, DKK 2 million). Mon, 09 Oct 2023 10:42:42 +0200 https://news.ki.se/comorbidity-between-neurodevelopmental-disorders-and-childhood-onset-type-1-diabetes Childhood-onset type 1 diabetes (onset Thu, 21 Sep 2023 10:56:27 +0200 https://news.ki.se/epidemiological-aspects-of-type-1-diabetes-early-life-origins-childhood-comorbidities-and-adult-outcomes Type 1 diabetes is an autoimmune disease, often with onset during childhood, that requires lifelong insulin therapy due to the loss of pancreatic beta-cells. Thu, 21 Sep 2023 09:00:39 +0200 https://news.ki.se/identification-of-a-direct-progenitor-population-for-differentiation-to-insulin-producing-cells The deficiency of functional insulin-producing cells is a common feature of type 1 and late-stage type 2 diabetes. Previous studies have suggested that mammals have very limited capacity for regeneration of insulin-producing cells, but researchers at Karolinska Institutet have found how zebrafish can form new cells and thereby provide clues to possible future possibilities in diabetes. The study is published in the scientific journal Science Advances. Mon, 21 Aug 2023 07:27:17 +0200 https://news.ki.se/the-controversial-nobel-prize-for-the-discovery-of-insulin-photo-documentary This year marks one hundred years since Frederick Banting and John MacLeod were awarded the Nobel prize for the discovery of insulin. The discovery has saved the lives of millions of people with diabetes worldwide, but the price is also one of the most debated. In their photo documentary, Professors Lars Rydén and Jan Lindsten talk about the history of the discovery, the problems associated with the award, and the importance the findings have had for today's treatment of diabetes. Mon, 29 May 2023 12:28:56 +0200 https://news.ki.se/childhood-obesity-linked-to-increased-risk-of-different-forms-of-diabetes-in-adulthood Child obesity is linked to increased risk of developing diabetes in adulthood, both autoimmune forms of diabetes and different forms of type 2 diabetes, a new study published in Diabetologia reports. The risk of developing the most insulin-resistant form of diabetes is, for example, three times as high in children with obesity. Tue, 28 Feb 2023 13:11:30 +0100 https://news.ki.se/women-and-men-have-different-risk-factors-for-type-2-diabetes Type 2 diabetes is a common disease, affecting 10 % of the adult world population, in which heredity and overweight are known risk factors. In a new study at Karolinska Institutet, researchers show that women and men with a predisposition to diabetes have different risk factors forecasting type 2 diabetes and prediabetes. The results were recently published in the journal Frontiers in Endocrinology. Mon, 13 Feb 2023 17:30:00 +0100 https://news.ki.se/antibody-candidate-for-treating-serious-liver-disease There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases. A study led by researchers from Karolinska Institutet has now identified a drug candidate for the treatment of fatty liver. The preclinical study, published in the Journal of Hepatology, indicates that an antibody that blocks the protein VEGF-B presents a possible therapeutic option for fatty liver disease. Fri, 03 Feb 2023 09:43:02 +0100 https://news.ki.se/in-memory-of-professor-suad-efendic Suad Efendic, Stockholm, internationally recognized leading clinical researcher in diabetes, has died at the age of 85 after a long illness. He is survived by wife Mensura, sons Nedim and Enes with their families. Tue, 20 Dec 2022 14:26:57 +0100 https://news.ki.se/new-study-explains-link-between-diabetes-and-utis Lower immunity and recurring infections are common in type 1 and type 2 diabetes. Researchers at Karolinska Institutet now show that the immune system of people with diabetes has lower levels of the antimicrobial peptide psoriasin, which compromises the urinary bladder’s cell barrier, increasing the risk of urinary tract infection. The study is published in Nature Communications. Tue, 20 Sep 2022 11:00:07 +0200 https://news.ki.se/individuals-with-type-2-diabetes-respond-differently-to-exercise Regular exercise helps prevent and delay the development of type 2 diabetes and its complications. Researchers at Karolinska Institutet have, together with a team of international scientists, discovered that activation of the immune system in skeletal muscle during exercise may underlie the difference in how individuals with type 2 diabetes perceive and respond to exercise. These findings are published in the journal Science Advances. Thu, 08 Sep 2022 06:30:04 +0200 https://news.ki.se/two-ki-researchers-receive-award-for-their-research-in-diabetes KI researchers Niklas Mejhert and Zhichao Zhou are among the 4 European grantees receiving 5 million DKK each for 5 years from the European Foundation for the Study of Diabetes (EFSD)/Novo Nordisk Future Leaders Award program in 2022. Wed, 24 Aug 2022 14:09:28 +0200 https://news.ki.se/in-vivo-drug-discovery-for-increasing-incretin-expressing-cells-in-diabetes A new study published in Cell Chemical Biology describes an alternative approach to treat diabetes by identifying drugs directly increasing the number of incretin-expressing cells. The work results from researchers at Karolinska Institutet. Tue, 23 Aug 2022 08:00:05 +0200 https://news.ki.se/type-1-diabetes-linked-to-higher-risk-of-mental-health-problems-in-patients-and-family Both children with type 1 diabetes and their closest family members are at increased risk of mental health problems compared with those without the disease, according to a large study by researchers at Karolinska Institutet published in the journal Diabetes Care. The findings underscore the need for psychological consulting for both children and their families in diabetes care. Mon, 01 Aug 2022 14:00:06 +0200 https://news.ki.se/diabetes-and-cardiovascular-disease-increase-dementia-risk People with at least two of the diseases type 2 diabetes, heart disease or stroke have double the risk of developing dementia. Prevention of diabetes and cardiovascular disease could therefore be a strategy for reducing dementia risk, a study from Karolinska Institutet published in the journal Alzheimer’s & Dementia suggests. Thu, 16 Jun 2022 13:00:04 +0200 https://news.ki.se/study-describes-new-way-of-generating-insulin-producing-cells Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis. The results are published in Nature Chemical Biology. Mon, 13 Jun 2022 17:00:06 +0200 https://news.ki.se/target-protein-for-diabetes-drug-linked-to-reduced-risk-of-alzheimers-disease Mechanisms associated with a particular diabetes drug can also help to protect against Alzheimer’s disease, a study by researchers at Karolinska Institutet and published in Neurology reports. The results indicate that the drug’s target protein can be an interesting candidate for the treatment of Alzheimer’s disease. Thu, 02 Jun 2022 22:00:07 +0200 https://news.ki.se/mini-kidneys-help-understand-the-link-between-diabetes-and-severe-covid-19 A team of scientists including at Karolinska Institutet has used mini-kidneys simulating those of diabetic patients to further our understanding of the link between diabetes and COVID-19. The researchers found that diabetic mini-kidneys have a higher susceptibility to SARS-CoV-2 infection than non-diabetic mini-kidneys. The study, which is published in the journal Cell Metabolism, also identified genetic evidence for the essential role of the ACE2 receptor in COVID-19. Thu, 12 May 2022 17:00:04 +0200 https://news.ki.se/new-strategy-to-preserve-insulin-producing-cells-in-diabetes High blood glucose is responsible for several complications in type 1 and type 2 diabetes. Researchers at Karolinska Institutet have identified a new antidiabetic substance that preserves the activity of insulin-producing beta cells and prevents high blood glucose in mice. The study is published in the journal Science Translational Medicine. Wed, 30 Mar 2022 20:00:11 +0200 https://news.ki.se/study-identifies-potential-new-approach-for-treating-diabetes-complications A new study from Karolinska Institutet sheds new light on how diabetes causes tissue damage when oxygen levels drop, and point to the repression of a protein complex as a possible treatment target for diabetes complications. The findings are published in the journal eLife. Tue, 15 Feb 2022 09:00:09 +0100 https://news.ki.se/myriam-aouadi-receives-award-for-outstanding-diabetes-research KI researcher Myriam Aouadi is awarded the Leif C. Groop award for her research about the mechanisms behind the development of non-alcoholic fatty liver disease in obese individuals with type 2 diabetes. Mon, 31 Jan 2022 08:51:26 +0100 https://news.ki.se/weight-loss-may-repair-the-brain-after-stroke-in-diabetes People with type 2 diabetes have an increased risk of stroke and slower recovery from it. Now, researchers at Karolinska Institutet have shown that neurological recovery from stroke is significantly improved in mice with obesity and diabetes who achieve weight loss to the extent that glucose metabolism returns to normal levels. The results are published in the scientific journal Cardiovascular Diabetology and may have clinical relevance for stroke rehabilitation in type 2 diabetes. Mon, 10 Jan 2022 13:55:36 +0100 https://news.ki.se/lack-of-important-molecule-in-red-blood-cells-causes-vascular-damage-in-type-2-diabetes Altered function of the red blood cells leads to vascular damage in type 2 diabetes. Results from a new study in cells from patients with type 2 diabetes and mice show that this effect is caused by low levels of an important molecule in the red blood cells. The study by researchers at Karolinska Institutet in Sweden has been published in the journal Diabetes. Tue, 09 Nov 2021 11:00:05 +0100 https://news.ki.se/mitochondria-of-diabetic-patients-cant-keep-track-of-time Muscle cells in patients with type 2 diabetes have a disrupted biological clock discover researchers at the University of Copenhagen and Karolinska Institutet. The findings, published in the journal Science Advances, suggest that treatments for type 2 diabetes may be more or less effective depending on the time of day they are given. Wed, 20 Oct 2021 20:53:38 +0200 https://news.ki.se/breastfeeding-linked-to-lower-risk-of-type-1-diabetes Research on the role of diet in the development of type 1 diabetes is generally of low evidence, but there are some high-quality studies indicating that longer breastfeeding and later introduction to gluten may reduce the risk of disease. That is according to a systematic review and meta-analysis of available research on foods that may be linked to the risk of developing the type 1 diabetes in childhood. The study by researchers at Karolinska Institutet is published in the journal EBioMedicine. Mon, 18 Oct 2021 14:14:35 +0200 https://news.ki.se/clarification-on-diabetes-and-dementia-risk It is mainly poorly controlled type 2 diabetes that carries an elevated risk of cognitive impairment and dementia, not the diabetes per se, a longitudinal study by researchers at Karolinska Institutet in Sweden shows. The study comprises over 2,500 people and is published in the journal Alzheimer’s & Dementia: The Journal of the Alzheimer's Association. Tue, 12 Oct 2021 13:00:04 +0200 https://news.ki.se/new-insight-on-the-link-between-obesity-and-type-2-diabetes It is well known that obesity affects the body's insulin production and over time risks leading to type 2 diabetes and several other metabolic diseases. Now researchers at Karolinska Institutet in Sweden have found further explanation for why fat cells cause metabolic morbidity. The study, published in Nature Medicine, may have an impact on the treatment of comorbidity in obesity with already available drugs. Mon, 04 Oct 2021 17:00:06 +0200 https://news.ki.se/juleen-zierath-awarded-the-claude-bernard-medal-and-lectureship Professor Juleen R. Zierath receives the 2021 prestigious EASD Claude Bernard Award. This award recognizes an individual’s innovative leadership and lifetime achievements in diabetes research and is the EASD’s highest award. Thu, 30 Sep 2021 12:57:33 +0200 https://news.ki.se/bionut-researcher-receives-efsd-novo-nordisk-future-leaders-award Assistant Professor Rongrong Fan at the Department of Biosciences and Nutrition is among the 4 grantees in Europe who have received 5 million DKK for 5 years from the EFSD / Novo Nordisk Future Leaders Award program in 2021. This highly competitive grant supports young and promising researchers of excellence who wish to further develop their career in Europe to investigate the mechanisms of diabetes. Wed, 18 Aug 2021 12:43:48 +0200 https://news.ki.se/ki-researchers-receive-efsdnovo-nordisk-foundation-future-leaders-awards-4 Assistant Professors Nicolas Pillon at Department of Physiology and Pharmacology and Rongrong Fan at Department of Biosciences and Nutrition have both been awarded the 2021 Future Leaders Award by EFSD (European Foundation for the Study of Diabetes)/Novo Nordisk Foundation. This is a competitive 5-year grant to support PIs to become future leaders in diabetes research. Tue, 17 Aug 2021 17:04:26 +0200 https://news.ki.se/only-one-human-fat-cell-subtype-responds-to-insulin-stimulation It is well known that fat cells can influence our sensitivity to insulin. Now, researchers at Karolinska Institutet in Sweden have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these, called AdipoPLIN, that responds to insulin. The findings may be relevant for future treatments of metabolic diseases such as Type 2 diabetes. Tue, 10 Aug 2021 17:00:05 +0200 https://news.ki.se/new-thesis-on-diabetes-metformin-and-gastric-adenocarcinoma Jiaojiao Zheng from the research group Upper GI Surgery, the Department of Molecular Medicine and Surgery, will defend her thesis "Diabetes, metformin and gastric adenocarcinoma" on June 11, 2021. Main Supervisor is Professor Jesper Lagergren. Tue, 08 Jun 2021 12:15:50 +0200 https://news.ki.se/apply-for-srp-diabetes-postdoctoral-fellowships With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. To promote cross-fertilization between research environments, we encourage scientists wishing to pursue postdoctoral training in a different university from where they carried out doctoral studies. Openings for fellowships in 5 different laboratories at Karolinska Institutet. Deadline June 6! Wed, 19 May 2021 15:17:04 +0200 https://news.ki.se/increased-risk-of-liver-cancer-in-patients-with-non-alcoholic-fatty-liver Non-alcoholic fatty liver disease, NAFLD, is associated with several health risks. According to a new registry study led by researchers at Karolinska Institutet in Sweden, NAFLD is linked to a 17-fold increased risk of liver cancer. The findings, published in Hepatology, underscore the need for improved follow-up of NAFLD patients with the goal of reducing the risk of cancer. Wed, 14 Apr 2021 09:06:02 +0200 https://news.ki.se/new-thesis-explores-how-older-adults-can-combat-diabetes-by-adopting-a-healthy-and-socially-active-lifestyle Hi there Ying Shang, PhD student at the Aging Research Center (ARC). You will be defending your thesis entitled “How can older adults combat diabetes to achieve a longer and healthier life?” on 16 April 2021. Could you tell us a little more about it? Thu, 25 Mar 2021 15:52:50 +0100 https://news.ki.se/diabetes-fridays-new-webinar-series SRP Diabetes organize a new webinar series - "Diabetes Fridays" with internationally recognized speakers in the area of diabetes and metabolism, often in combination with a talk by a researcher from KI or UmU on a similar topic as the external guest. Fri, 19 Mar 2021 15:16:56 +0100 https://news.ki.se/metabolic-derangements-caused-by-a-high-fat-diet-may-be-possible-to-eliminate Intake of a high-fat diet leads to an increased risk for obesity, type 2 diabetes, cardiovascular diseases and fatty liver. A study in mice from Karolinska Institutet shows that it is possible to eliminate the deleterious effects of a high-fat diet by lowering the levels of apolipoprotein CIII (apoCIII), a key regulator of lipid metabolism. The study is published in the journal Science Advances. Fri, 12 Mar 2021 20:00:04 +0100 https://news.ki.se/juleen-zierath-receives-the-harold-rifkin-award SRP Diabetes PI Juleen R. Zierath receives the 2021 Harold Rifkin Award for Distinguished International Service in the Cause of Diabetes from American Diabetes Association (ADA). Wed, 10 Mar 2021 14:37:32 +0100 https://news.ki.se/new-thesis-about-diabetes-mellitus-in-patients-with-dementia Hi Juraj Sečník, PhD student at the Division of Clinical Geriatrics! On January 29 you will defend your thesis “Diabetes mellitus in patients with dementia : clinical care and pharmacological treatment”. What’s the main focus of the thesis? Wed, 13 Jan 2021 10:06:51 +0100 https://news.ki.se/findings-about-hair-like-structures-on-cells-inside-vessels-may-be-relevant-for-diabetes-treatment A new study from Karolinska Institutet and the Helmholtz Diabetes Research Center shows that primary cilia, hair-like protrusions on endothelial cells inside vessels, play an important role in the blood supply and delivery of glucose to the insulin-producing beta cells in the pancreatic islets. The findings are published in eLife and may be relevant for transplantation therapies in diabetes, as formation of functional blood vessels is important for the treatment to be successful. Fri, 04 Dec 2020 10:23:12 +0100 https://news.ki.se/improved-survival-after-obesity-operation-in-patients-with-previous-myocardial-infarction Researchers at Karolinska Institutet and Danderyd Hospital have studied the risk of additional myocardial infarctions and early death in severely obese patients who undergo metabolic surgery following a myocardial event. The registry study covering 1,018 individuals shows a lower risk of additional myocardial infarctions and improved survival that cannot be simply attributed to the loss of weight. The study is published in the journal Circulation. Mon, 26 Oct 2020 10:00:04 +0100 https://news.ki.se/novo-nordisk-foundation-project-grant-of-dkk-2-million-to-nils-goran-larsson Nils-Göran Larsson receives a project grant in Endocrinology & Metabolism of DKK 2 million from the Novo Nordisk Foundation. We’ve talked to him about the project that investigates the role of mitochondria in the development of obesity-associated insulin resistance. Wed, 23 Sep 2020 12:43:55 +0200 https://news.ki.se/possible-vaccine-for-virus-linked-to-type-1-diabetes According to many observations, certain virus infections may play a part in the autoimmune attack that leads to type 1 diabetes. Researchers at Karolinska Institutet in Sweden and their Finnish colleagues have now produced a vaccine for these viruses in the hope that it could provide protection against the disease. The study is published today in the scientific journal Science Advances. Wed, 06 May 2020 20:00:06 +0200 https://news.ki.se/certain-diabetes-drugs-may-protect-against-serious-kidney-problems Use of sodium glucose cotransporter 2 (SGLT2) inhibitors to treat type 2 diabetes may help to lower the risk of serious kidney problems, according to a Scandinavian study led by researchers at Karolinska Institutet. The findings, now published in the journal The BMJ, provide support for the use of SGLT2 inhibitors in a broad range of patients with type 2 diabetes, according to the researchers. Thu, 30 Apr 2020 09:19:37 +0200 https://news.ki.se/wallenberg-clinical-scholars-for-research-on-rheumatoid-arthritis-and-fat-cells-change Two clinical researchers at KI have been appointed Wallenberg Clinical Scholars 2020. The individual funding of SEK 15 million from Knut and Alice Wallenberg Foundation provides Anca Catrina and Mikael Rydén with the opportunity to deepen their research and disseminate their results in healthcare. Mon, 23 Mar 2020 09:06:45 +0100 https://news.ki.se/professor-franz-matschinsky-receives-the-rolf-luft-award-2020 Dr Franz Matschinsky, Professor of Biochemistry and Biophysics, Institute for Diabetes, Obesity and Metabolism Perelman School of Medicine, Philadelphia receives the 2020 Rolf Luft Award for the discovery that glucokinase (GK) is the sensor controlling glucose-stimulated insulin secretion in the pancreatic beta cell. Thu, 20 Feb 2020 12:44:33 +0100 https://news.ki.se/calcium-channels-play-a-key-role-in-the-development-of-diabetes Researchers at Karolinska Institutet have deciphered the diabetogenic role of a certain type of calcium channel in insulin-secreting beta cells. The researchers believe that blockade of these channels could be a potential new treatment strategy for diabetes. The study is published in the scientific journal PNAS. Mon, 23 Dec 2019 21:00:00 +0100 https://news.ki.se/new-clues-to-the-link-between-als-and-type-2-diabetes Patients with ALS (amyotrophic lateral sclerosis) often suffer from type 2 diabetes. This phenomenon has since long remained mechanistically enigmatic. Now, researchers at Karolinska Institutet in Sweden have identified a molecular mechanism linking these two diseases. The study is published in the scientific journal PNAS. Mon, 09 Dec 2019 21:00:00 +0100 https://news.ki.se/the-discovery-that-was-awarded-this-years-nobel-prize-in-physiology-or-medicine-is-hugely-important-to-research-on-diabetes-complications Hello there, Sergiu Catrina - Associate Professor, Specialist Physician and Research Leader for the Growth and Metabolism Group at the Department of Molecular Medicine and Surgery. Mon, 21 Oct 2019 11:08:13 +0200 https://news.ki.se/weight-loss-surgery-cuts-risk-of-major-birth-defects Children born to women who underwent gastric bypass surgery before becoming pregnant had a lower risk of major birth defects than children born to women who had severe obesity at the start of their pregnancy. That’s according to a matched cohort study by researchers at Karolinska Institutet and Örebro University published in the scientific journal JAMA. The findings indicate that weight-loss and improved blood sugar control could reduce the risk of major birth defects. Tue, 15 Oct 2019 17:00:00 +0200 https://news.ki.se/increased-risk-of-type-2-diabetes-in-some-occupations Drivers, factory workers, and cleaners are three times more likely to develop type 2 diabetes than teachers and physiotherapists. Researchers at Karolinska Institutet in Sweden have studied how the occurrence of diabetes differs between occupations in Sweden. The results are being published in the scientific journal Diabetologia and are also presented at the European diabetes conference in Barcelona in September. Wed, 18 Sep 2019 08:00:00 +0200 https://news.ki.se/lower-risk-for-heart-failure-with-new-type-2-diabetes-drug The new type of drugs for type 2 diabetes, the so-called SGLT2 inhibitors, are associated with a reduced risk of heart failure and death as well as of major cardiovascular events, a major Scandinavian registry study led from Karolinska Institutet reports in The BMJ. Thu, 29 Aug 2019 13:27:54 +0200 https://news.ki.se/the-swedish-society-of-medicine-awards-maternal-glycemic-control-in-type-1-diabetes-and-the-risk-of-preterm-birth-the-alvarenga-prize-2019-for-best-medical-paper The paper's motto was: ”Among women with diabetes and high HbA1c, there is a risk that the fetus too early the outside world will see” The winning study was led by Professor Jonas F Ludvigsson, Department of Medical Epidemiology and Biostatistics, KI, and shows that pregnant women with type 1 diabetes are at increased risk of pregnancy complications, including preterm birth. With increasing HbA1c the risk of preterm birth increased further. Fri, 23 Aug 2019 11:07:04 +0200 https://news.ki.se/novel-findings-explain-indirect-regulation-of-glucose-homeostasis The hormone secreting part of the pancreas, the islets of Langerhans, has a unique cyto-architecture that allows functional interrelationships between the different cell types. Somatostatin is secreted by the delta cell and is an effective inhibitor of the insulin secreting beta cell and the glucagon secreting alpha cell. According to a novel study from Karolinska Instiutet, published in the journal Nature Communications, the delta cell can thereby indirectly affect glucose homeostasis Fri, 16 Aug 2019 10:58:11 +0200 https://news.ki.se/undetected-diabetes-linked-to-heart-attack-and-gum-disease People with undetected glucose disorders run a higher risk of both myocardial infarction and periodontitis, according to a study published in the journal Diabetes Care by researchers at Karolinska Institutet. The results demonstrate the need of greater collaboration between dentistry and healthcare, say the researchers, and possibly of screening for diabetes at dental clinics. Mon, 10 Jun 2019 10:35:11 +0200 https://news.ki.se/transplanted-cells-reveal-early-signs-of-type-1-diabetes By the time type 1 diabetes is diagnosed, most of the insulin-producing beta cells have already been destroyed. Now, using an innovative transplantation technique, researchers at Karolinska Institutet and University of Miami Miller School of Medicine have been able to intervene to save the beta cells in mice by discovering early signs of the disease. The study is published in Diabetologia, the scientific journal of the European Association for the Study of Diabetes (EASD). Wed, 15 May 2019 15:03:12 +0200 https://news.ki.se/pregnant-women-with-type-1-diabetes-are-at-risk-of-giving-birth-prematurely Pregnant women with type 1 diabetes are at increased risk of delivering their baby prematurely. The risk increases as blood sugar levels rise, however women who maintain the recommended levels also risk giving birth prematurely. These are the findings from researchers at Karolinska Institutet and the Sahlgrenska Academy in Sweden, published in Annals of Internal Medicine. Tue, 23 Apr 2019 13:13:21 +0200 https://news.ki.se/erc-grant-for-research-on-insulin-producing-cells The ERC Advanced Grant is one of the most prestigious funding programmes for research in Europe. Per-Olof Berggren, professor of experimental endocrinology at Karolinska Institutet, is now awarded this grant for the second time. Thu, 28 Mar 2019 12:05:00 +0100 https://news.ki.se/mechanism-of-impaired-wound-healing-in-diabetes-identified Tue, 26 Mar 2019 07:44:02 +0100 https://news.ki.se/olov-andersson-recipient-of-the-leif-c-groop-award-for-outstanding-diabetes-research Olov Andersson, docent at the Department of Cell and Molecular Biology at Karolinska Institutet, is the recipient of The Leif C. Groop award for outstanding research for his research in zebrafish that could lead to new treatments for diabetes. Awarded by the Lund University Diabetes Centre and sponsored by Novo Nordisk Sweden. Wed, 06 Mar 2019 13:12:19 +0100 https://news.ki.se/professor-mitchell-lazar-receives-the-2019-rolf-luft-award Professor Mitchell Lazar at Perelman School of Medicine, University of Pennsylvania, Philadelphia has been selected as recipient of the Rolf Luft Award 2019. Wed, 13 Feb 2019 13:09:37 +0100 https://news.ki.se/newly-discovered-disease-opens-for-future-diabetes-treatment Knowledge of a newly discovered genetic disorder, which means that a person cannot produce the protein TXNIP (thioredoxin interacting protein) in their cells, can open for the development of new diabetes drugs. This is shown in a study from Karolinska Institutet published in the journal Diabetes. Tue, 12 Feb 2019 11:01:30 +0100 https://news.ki.se/short-anti-rejection-therapy-protects-transplants-in-diabetic-animals Fri, 01 Feb 2019 06:00:01 +0100 https://news.ki.se/diabetes-drug-liraglutide-linked-to-lower-risk-of-cardiovascular-events Thu, 06 Dec 2018 07:00:43 +0100 https://news.ki.se/myriam-aouadi-awarded-the-prestigious-heldi-award . Fri, 23 Nov 2018 14:11:39 +0100 https://news.ki.se/new-diabetes-drug-may-increase-the-risk-of-serious-adverse-events Thu, 15 Nov 2018 06:00:01 +0100 https://news.ki.se/sharing-of-knowledge-from-an-international-project-on-how-to-manage-your-type-2-diabetes Fri, 12 Oct 2018 13:15:08 +0200 https://news.ki.se/red-blood-cells-cause-cardiovascular-injury-in-type-2-diabetes Mon, 06 Aug 2018 20:05:22 +0200 https://news.ki.se/new-potential-target-for-treatment-of-diabetes Tue, 24 Jul 2018 17:00:00 +0200 https://news.ki.se/higher-risk-of-heart-defects-in-babies-of-mothers-with-type-1-diabetes Thu, 05 Jul 2018 06:00:00 +0200 https://news.ki.se/the-bodys-glucostat-identified It is the pancreatic islets that have the overall responsibility for maintaining normal blood glucose levels in our bodies, according to a new study by researchers at Karolinska Institutet and the University of Miami Miller School of Medicine, USA. The findings, published in the scientific journal Cell Metabolism, have important implications for certain diabetes treatments. Tue, 06 Mar 2018 18:00:00 +0100 https://news.ki.se/female-sex-not-a-protective-factor-against-heart-disease-in-type-1-diabetes Tue, 20 Feb 2018 16:00:00 +0100 https://news.ki.se/jorge-ruas-recipient-of-the-leif-c-groop-award-for-outstanding-diabetes-research Jorge Ruas, Associate Professor at the Department of Physiology and Pharmacology at Karolinska Institutet, is the recipient of The Leif C. Groop award for outstanding diabetes research for his work on muscle and exercise physiology and critical signalling pathways in skeletal muscle, liver and fat tissue. Wed, 17 Jan 2018 17:03:35 +0100 https://news.ki.se/two-ki-researchers-to-receive-erc-consolidator-grants-2017 Tue, 28 Nov 2017 14:02:32 +0100 https://news.ki.se/enterovirus-vaccine-prevented-type-1-diabetes-in-mice Mon, 20 Nov 2017 13:00:00 +0100 https://news.ki.se/new-research-highlights-how-our-neurons-can-become-insulin-resistant-and-the-connection-to-alzheimer-disease Tue, 24 Oct 2017 14:52:28 +0200 https://news.ki.se/coronary-artery-bypass-surgery-effective-in-patients-with-type-1-diabetes Mon, 28 Aug 2017 14:48:20 +0200 https://news.ki.se/method-developed-that-gives-researchers-better-conditions-for-studying-insulin-producing-cells Wed, 09 Aug 2017 16:14:27 +0200 https://news.ki.se/hormone-from-fat-tissue-can-give-protection-against-pcos Obesity and reduced insulin sensitivity are common in polycystic ovary syndrome, PCOS. New research based on animal studies, and to be published in the journal PNAS, reveals that the hormone adiponectin can protect against these changes. Wed, 09 Aug 2017 13:42:57 +0200 https://news.ki.se/serious-kidney-disease-can-be-retarded Wed, 08 Feb 2017 21:16:22 +0100 https://news.ki.se/snus-users-run-greater-risk-of-type-2-diabetes Mon, 06 Feb 2017 06:05:20 +0100 https://news.ki.se/fat-degrading-enzyme-implicated-in-type-2-diabetes Investigators at Karolinska Institutet have identified a potential therapeutic target for treatment of obesity-associated metabolic diseases such as type 2 diabetes and nonalcoholic hepatic steatosis. The work, performed in collaboration with scientists at the University of California, Berkeley and Danderyd Hospital, is published in Cell Reports. Tue, 17 Jan 2017 18:05:00 +0100 https://news.ki.se/sweetened-beverages-increase-the-risk-of-autoimmune-diabetes Wed, 26 Oct 2016 09:31:59 +0200 https://news.ki.se/unique-molecular-atlas-of-pancreas-produced Fri, 23 Sep 2016 11:15:23 +0200 https://news.ki.se/new-technique-improves-blood-sugar-control-for-people-with-diabetes Mon, 12 Sep 2016 10:45:57 +0200 https://news.ki.se/epigenomic-alterations-contribute-to-obesity-associated-diabetes Mon, 06 Jun 2016 17:00:00 +0200 https://news.ki.se/new-non-invasive-method-for-studying-the-development-of-insulin-producing-cells Mon, 04 Apr 2016 14:12:25 +0200 https://news.ki.se/insulin-secreting-cells-report-on-insulin-resistance Mon, 22 Feb 2016 11:12:00 +0100 https://news.ki.se/type-2-diabetes-drug-can-exhaust-insulin-producing-cells Fri, 12 Feb 2016 08:00:00 +0100 https://news.ki.se/new-knowledge-on-why-patients-with-type-2-diabetes-present-smelling-problems In a study in type 2 diabetic rats, researchers at the Karolinska Institutet have identified alterations in specific nerve cells that are important for odor identification. The findings might explain why type 2 diabetic patients often experience smelling problems and potentially open up a new research field to develop preventive therapies against neurodegenerative diseases in type 2 diabetic patients. Wed, 20 Jan 2016 15:12:33 +0100 https://news.ki.se/novel-mechanism-of-insulin-resistance-in-type-2-diabetes Thu, 17 Sep 2015 18:05:00 +0200 https://news.ki.se/type-2-diabetic-patients-should-be-prioritised-for-obesity-surgery Thu, 17 Sep 2015 09:10:00 +0200 https://news.ki.se/new-finding-on-the-formation-of-fat-tissue-in-man Thu, 16 Jul 2015 18:00:00 +0200 https://news.ki.se/new-knowledge-about-how-type-2-diabetes-develops Tue, 19 May 2015 08:16:00 +0200 https://news.ki.se/rolf-luft-award-2015-goes-to-professor-andrew-hattersley Wed, 22 Apr 2015 13:00:56 +0200 https://news.ki.se/novo-nordisk-and-karolinska-institutet-join-forces-in-the-field-of-diabetes Tue, 10 Feb 2015 11:45:00 +0100 https://news.ki.se/young-vessels-rejuvenate-aged-insulin-producing-beta-cells Tue, 18 Nov 2014 08:30:16 +0100 https://news.ki.se/study-explains-the-link-between-cilia-and-diabetes Thu, 06 Nov 2014 11:01:00 +0100