https://ki.se RSS News Listing https://news.ki.se/high-meat-consumption-linked-to-lower-dementia-risk-in-genetic-risk-group Older people with a genetic risk of Alzheimer's disease did not experience the expected increase in cognitive decline and dementia risk if they consumed relatively large amounts of meat. This is shown in a new study from Karolinska Institutet published in JAMA Network Open. The results may contribute to the development of more individually tailored dietary advice. Thu, 19 Mar 2026 16:00:16 +0100 https://news.ki.se/exercise-and-nutritional-drinks-can-reduce-the-need-for-care-in-dementia A simple combination of daily physical exercise and protein-rich nutritional drinks appears to offer significant health benefits for people with dementia. In a new study from Karolinska Institutet, not only did the participants' physical ability improve, but after three months the researchers also saw signs that they were able to manage more everyday tasks themselves. The study is published in the journal Alzheimer's and Dementia. Wed, 18 Feb 2026 08:55:26 +0100 https://news.ki.se/kidney-function-may-affect-alzheimers-blood-biomarkers People with lower kidney function may have higher levels of several blood markers often used in research on Alzheimer’s disease and related dementias. This is shown in a new systematic review and meta‑analysis published in The Journal of the American Society of Nephrology. Thu, 12 Feb 2026 12:16:35 +0100 https://news.ki.se/mutation-type-shapes-early-alzheimers-0 How hereditary Alzheimer’s disease develops in its early stages depends on which genetic mutation a person carries. This is shown in a new study from Karolinska Institutet, published in the journal Translational Psychiatry. Fri, 06 Feb 2026 09:48:49 +0100 https://news.ki.se/bill-gates-visits-kis-alzheimers-researchers Bill Gates visited Karolinska Institutet and Karolinska University Hospital last Friday at his own initiative to discuss the latest advances in Swedish Alzheimer’s research, a field that interests him and that he supports. Tue, 27 Jan 2026 11:50:52 +0100 https://news.ki.se/kidney-health-affects-alzheimers-blood-biomarkers-but-not-dementia-risk Older adults with reduced kidney function show higher levels of Alzheimer’s-related biomarkers in the blood, but are not more likely to develop dementia, according to a new study from Karolinska Institutet. Thu, 04 Dec 2025 15:41:46 +0100 https://news.ki.se/study-finds-common-health-conditions-can-influence-alzheimers-blood-tests How do everyday health issues affect new blood tests for Alzheimer’s disease? A study from Karolinska Institutet, in Alzheimer's & Dementia, suggests that factors like kidney function, cholesterol, and diabetes can influence some of these biomarkers—though the most promising marker remains reliable. Tue, 02 Dec 2025 09:03:07 +0100 https://news.ki.se/discovery-about-brain-receptors-may-open-the-door-to-new-alzheimers-treatments Researchers at Karolinska Institutet in Sweden and the RIKEN Center for Brain Science in Japan have identified two receptors in the brain that control the breakdown of amyloid beta, a substance that accumulates in Alzheimer’s disease. According to the researchers, the study could pave the way for future drugs that are both safer and cheaper than current antibody treatments. Fri, 28 Nov 2025 09:22:03 +0100 https://news.ki.se/how-arc-emerged-25-years-ago The Aging Research Center (ARC) was established in the year 2000, at a time when geriatric research was still in its infancy and little was known about dementia-related diseases. This happened during a period when politicians and decision-makers began to take an interest in the growing ageing population and the challenges that were becoming apparent in healthcare and social care as a result. Thu, 20 Nov 2025 15:04:54 +0100 https://news.ki.se/new-thesis-on-polypharmacy-sex-and-aging Hi Francesca Eroli, doctoral student at the Division of Neurogeriatrics. On November 7 november you will defend your thesis ”Toward precision medicine : sex-specific effects of multi-drug therapies in mouse models of aging and Alzheimer's pathology” What is the main focus of the thesis? Thu, 30 Oct 2025 11:01:51 +0100 https://news.ki.se/a-new-partnership-between-nvs-and-institute-of-development-aging-and-cancer-idac-tohoku-university-japan It is exciting to announce that NVS has signed a Memorandum of Understanding (MoU) with IDAC for academic exchange and to further strengthen the academic ties between the two institutions. The MoU was signed on August 11th, 2025, by Professor Maria Ankarcrona, Head of Department, NVS and Professor Kozo Tanaka, Director of IDAC. Wed, 29 Oct 2025 12:59:11 +0100 https://news.ki.se/new-brain-imaging-technique-can-detect-early-frontotemporal-dementia A new international study led by researchers at Karolinska Institutet demonstrates that it is possible to detect subtle changes in the brain and identify early signs of hereditary frontotemporal dementia using advanced brain imaging techniques. The study has recently been published in Molecular Psychiatry. Wed, 15 Oct 2025 09:54:45 +0200 https://news.ki.se/hm-the-queen-awards-ki-trained-dementia-specialists On September 2, 2025, seven physicians, five occupational therapists, and five physiotherapists were awarded diplomas by H.M. The Queen during a formal ceremony at Drottningholm Court Theatre. The ceremony marked the completion of the Master's courses in dementia care developed by Karolinska Institutet in close collaboration with Stiftelsen Silviahemmet. The participants may now use the titles Silvia Physician, Silvia Occupational Therapist, and Silvia Physiotherapist. Mon, 08 Sep 2025 10:26:19 +0200 https://news.ki.se/30-million-sek-from-wellcome-leap-care-for-research-with-a-comprehensive-perspective-on-alzheimers-disease-risk Shireen Sindi at NVS and her team have been awarded this major award. It is the first time an applicant from Karolinska Institutet (KI) has received such a large award from Wellcome Leap, with whom KI has had an agreement since 2021. Thu, 14 Aug 2025 12:46:35 +0200 https://news.ki.se/protein-from-bacteria-appears-to-slow-the-progression-of-alzheimers-disease A protein from the bacterium Helicobacter pylori has been shown to block the formation of harmful protein aggregates - known as amyloids - that are linked to Alzheimer's, Parkinson's and type 2 diabetes, among other diseases, and bacterial infections. This is the result of a new study published in the journal Science Advances. Thu, 12 Jun 2025 11:20:12 +0200 https://news.ki.se/new-thesis-on-biological-signatures-risk-profiles-and-prevention-of-dementia Hi Vilma Alanko, doctoral student at the Division of Clinical Geriatrics. On June 13 you will defend your thesis ”Translational studies on biological signatures, risk profiles, and prevention of dementia.” What is the main focus of the thesis? Mon, 09 Jun 2025 10:49:35 +0200 https://news.ki.se/long-partnership-with-johnson-johnson-paves-way-for-therapies-of-the-future The partnership between Johnson & Johnson Innovative Medicine (J&J) and Karolinska Institutet (KI) marks this year a decade of joint initiatives for promoting the development of tomorrow’s therapies. This long-standing collaboration between industry and academy has given rise to significant scientific advances in several fields of medicine. Mon, 19 May 2025 13:32:10 +0200 https://news.ki.se/the-svedberg-prize-2025-to-ki-researcher-michael-landreh The 2025 Svedberg Prize is awarded to Michael Landreh, Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet, "for the development and innovative use of mass spectrometric tools that reveal hidden protein interactions." Mon, 05 May 2025 16:55:43 +0200 https://news.ki.se/blood-test-may-rule-out-future-dementia-risk Researchers at Karolinska Institutet have demonstrated how specific biomarkers in the blood can predict the development of dementia up to ten years before diagnosis, among older adults living independently in the community. Wed, 02 Apr 2025 08:51:24 +0200 https://news.ki.se/common-multi-medication-therapies-affect-alzheimers-disease-pathology-differently-in-male-and-female-mice Certain widely used drug combinations may either slow down or worsen the progression of Alzheimer’s disease, but their effects differ between sexes. A new study from Karolinska Institutet, published in the leading journal Alzheimer’s & Dementia, highlights these important findings. Thu, 27 Mar 2025 17:21:03 +0100 https://news.ki.se/antidepressants-linked-to-faster-cognitive-decline-in-dementia New research suggests that antidepressants can accelerate cognitive decline in people with dementia. At the same time, some drugs appear to be less harmful than others, which can help doctors make better treatment decisions, according to the study published in BMC Medicine. Tue, 25 Feb 2025 07:54:40 +0100 https://news.ki.se/new-study-shows-link-between-rheumatoid-arthritis-and-cognitive-decline-in-dementia A new Swedish study has, for the first time, shown a link between rheumatoid arthritis (RA) and cognitive decline in dementia patients. The study, published in the scientific journal Neurology, emphasizes the importance of careful monitoring and management to prevent cognitive decline. Mon, 10 Feb 2025 11:02:02 +0100 https://news.ki.se/queen-silvias-birthday-present-a-day-about-dementia-research On 30 January, a symposium on dementia was held in honour of HM Queen Silvia at Karolinska Institutet. The event was part of the "experience gift" that KI presented in connection with the Queen’s 80th birthday. Mon, 03 Feb 2025 19:02:50 +0100 https://news.ki.se/poor-vascular-health-accelerates-brain-ageing Using an AI tool, researchers at Karolinska Institutet have analysed brain images from 70-year-olds and estimated their brains’ biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance. The results are presented in Alzheimer's & Dementia: The Journal of the Alzheimer's Association. Fri, 20 Dec 2024 13:00:20 +0100 https://news.ki.se/new-insights-into-alzheimers-disease-biomarkers How are emerging plasma biomarkers related to the diagnostic tests currently used in clinical routines? And does the earlier evidence from highly selective research cohorts translate to the heterogeneous real-world data? Researchers at Karolinska Institutet have sought to answer these questions in a study published in eBioMedicine with Dr. Marina Bluma from the Department of Neurobiology, Care Sciences and Society as the first author. Thu, 19 Dec 2024 08:11:34 +0100 https://news.ki.se/mats-paulsson-foundations-allocate-sek-10-million-to-alzheimers-research-at-ki The Mats Paulsson Foundations award Jan Johansson, professor at the Department of Medicine, Huddinge, Karolinska Institutet, SEK 10 million for research into new innovative treatment methods for Alzheimer's disease. The aim of the research project is to create a new drug that can achieve a breakthrough in the treatment of the most common dementia disease. Fri, 13 Dec 2024 12:58:19 +0100 https://news.ki.se/six-researchers-at-nvs-receive-grants-from-the-swedish-brain-foundation-2024 The Swedish Brain Foundation has awarded its grants. NVS received five research grants and one scholarship. Thu, 14 Nov 2024 14:03:55 +0100 https://news.ki.se/lars-olof-wahlund-awarded-the-bengt-winblad-prize-2024 The Swedish Society of Medicine (SLS) awards Professor Lars-Olof Wahlund, Karolinska Institutet, the Bengt Winblad Prize 2024. The prize honors outstanding contributions in Alzheimer’s research, and Lars-Olof Wahlund is seen as a pioneer in MRI imaging of the brain. Fri, 11 Oct 2024 14:09:06 +0200 https://news.ki.se/world-leading-alzheimers-researchers-celebrated-the-goodes-prize-at-ki Some of the world’s most prominent Alzheimer’s researchers congregated recently in Stockholm for the tenth anniversary of the prestigious Goodes Prize. The programme included a seminar day and a study visit to Karolinska Institutet followed by a social event in Stockholm City Hall. Thu, 19 Sep 2024 16:46:57 +0200 https://news.ki.se/new-study-sheds-light-on-alzheimers-disease-progression A groundbreaking study from Karolinska Institutet, recently published in the journal Molecular Psychiatry offers new insights into the progression of Alzheimer’s disease (AD). The research reveals critical differences in the progression of memory loss based on the presence of specific proteins in the brain. Fri, 06 Sep 2024 11:50:19 +0200 https://news.ki.se/duloxetine-may-help-elderly-with-depression-and-cognitive-impairment Karolinska Institutet has discovered that an already registered antidepressant, duloxetine, may also have positive effects on memory and cognitive functions in the elderly. Thu, 29 Aug 2024 09:45:48 +0200 https://news.ki.se/per-nilsson-recieves-200-000-usd-from-cure-alzheimers-fund-in-usa Per Nilsson, docent at the Division of Clinical Geriatrics, receives this amount together with Evandro Fang at the University of Oslo. Additionally, the funding is 200,000 USD per year for two years with the possibility of extension. Tue, 27 Aug 2024 15:25:24 +0200 https://news.ki.se/taher-darreh-shori-receives-nearly-2-million-sek-from-the-alzheimers-association He receives the grant for the project ‘Preclinical Evaluation of Potential Cholinergic PET Imaging Tracers’ and it is valid for a three-year period. Thu, 22 Aug 2024 08:55:26 +0200 https://news.ki.se/new-thesis-investigates-the-potential-relationship-between-indicators-of-chronic-stress-and-alzheimers-disease Hi Jasper Holleman, doctoral student at the Division of Clinical Geriatrics. On June 18 you will defend your thesis "Novel biomarkers associated with stress : from normal aging to Alzheimer's disease ". What is the main focus of the thesis? Wed, 12 Jun 2024 12:52:08 +0200 https://news.ki.se/new-thesis-investigates-the-relationship-between-autophagy-and-amyloid-b-and-tau-proteins-in-alzheimers-disease Hi Johanna Mayer, doctoral student at the Division of Neurogeriatrics. On June 17 you will defend your thesis "The role of autophagy in Aβ and tau metabolism in Alzheimer’s disease ". What is the main focus of the thesis? Wed, 12 Jun 2024 12:22:00 +0200 https://news.ki.se/how-stress-knocks-out-your-cognitive-reserve While mentally stimulating activities and life experiences can improve cognition in memory clinic patients, stress undermines this beneficial relationship. This is according to a new study from Karolinska Institutet published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. Tue, 04 Jun 2024 13:00:15 +0200 https://news.ki.se/ministerial-visit-focuses-on-alzheimers-disease Minister for Health Care Acko Ankarberg Johansson and Minister for Older People and Social Security Anna Tenje recently visited BioClinicum at Karolinska Institutet to learn more about the current status of Alzheimer’s research. "We’re getting closer to being able to devise an effective treatment," says Bengt Winblad, professor at the Department of Neurobiology, Care Sciences and Society, who hosted the visit. Fri, 22 Mar 2024 16:28:29 +0100 https://news.ki.se/new-study-links-dek-protein-to-alzheimers-neuronal-vulnerability A new study from Karolinska Institutet, published in Brain, reveals a connection between the protein DEK and early neuronal changes in Alzheimer’s disease. Researchers found that lower DEK levels in vulnerable neurons lead to altered neuronal activity and Tau protein accumulation, offering insights into early-stage Alzheimer’s pathology and potential therapeutic targets. Wed, 13 Mar 2024 11:31:28 +0100 https://news.ki.se/progress-in-spotting-early-signs-of-alzheimers-disease Researchers at Karolinska Institutet have made exciting discoveries about Alzheimer's disease, a common form of dementia affecting millions of people around the world. In a study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, they have explored the potential of novel synaptic PET-tracer UCB-J as an important early diagnostic biomarker/tool for Alzheimer's disease. Fri, 16 Feb 2024 13:09:57 +0100 https://news.ki.se/ki-in-international-collaboration-to-prevent-alzheimers-disease Karolinska Institutet is one of 24 partners in AD-RIDDLE, a collaborative project that aims to increase healthcare providers' ability to diagnose, prevent and treat Alzheimer's disease. The project, supported by, among others, the EU's Innovative Health Initiative (IHI), started in January 2024 and will run for five years. Thu, 15 Feb 2024 16:14:15 +0100 https://news.ki.se/how-a-natural-protein-can-help-fight-alzheimers-disease A new study published in Nature Communications gives insights into the underlying mechanisms of the formation of protein clumps in Alzheimer’s disease. The study, led by researchers from Karolinska Institutet, could pave the way for new treatments for this devastating neurodegenerative disorder. Fri, 02 Feb 2024 10:17:28 +0100 https://news.ki.se/consortium-collaborating-to-enhance-detection-prevention-and-treatment-of-alzheimers-disease Karolinska Institutet is part of the AD-RIDDLE consortium, a project dedicated to increasing health professional’s capabilities to detect, diagnose, prevent, and treat Alzheimer’s disease. Funded by the EU Innovative Health Initiative (IHI) and the UK Research and Innovation (UKRI), the project was launched in January 2024, includes 24 partners, and will run over five years. Thu, 01 Feb 2024 17:05:51 +0100 https://news.ki.se/protein-activation-in-the-brain-may-protect-women-against-alzheimers A new study at the Karolinska Institutet suggests that activation of a certain brain protein can protect women from developing neurodegenerative diseases such as Alzheimer's disease. Thu, 25 Jan 2024 07:37:07 +0100 https://news.ki.se/new-thesis-on-tau-pathology-in-alzheimers-disease-and-other-dementias Hi Mona-Lisa Malarte, doctoral student at the Division of Clinical Geriatrics. Om January 26 you will defend your thesis ”Tau pathology in Alzheimer's disease and other dementias : translational approach from in vitro autoradiography to in vivo PET imaging”. What is the main focus of the thesis? Tue, 23 Jan 2024 15:50:41 +0100 https://news.ki.se/finding-that-statins-could-slow-dementia-stimulates-further-research Blood fat-lowering statins could slow the progression of Alzheimer's disease, at least for some patients. This is the result of a new study led by Karolinska Institutet published in Alzheimer Research and Therapy. But the researchers are cautious in their interpretations and see the results as a first step in a research journey that may eventually provide the answer. Wed, 20 Dec 2023 10:07:37 +0100 https://news.ki.se/unique-project-to-create-better-decision-support-for-dementia-care Dementia diseases cost Swedish society around SEK 80 billion per year. The EU has now awarded funding to the Prominent project, which aims to improve both diagnostics and treatment for these diseases. Karolinska Institutet is responsible for the project in the role of coordinator. Thu, 14 Dec 2023 11:12:34 +0100 https://news.ki.se/high-metabolism-is-an-early-sign-of-alzheimers-disease An early phase in the process of developing Alzheimer’s disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry. The discovery opens up for new potential methods of early intervention. Wed, 01 Nov 2023 10:11:35 +0100 https://news.ki.se/new-thesis-on-proteins-that-influence-the-progression-of-alzheimers-disease Hi Michael Axenhus, PhD student at the Division of Neurogeriatrics. On October 20 you will defend your thesis ”Characterization of proteins involved in disease progression in Alzheimer disease”, what is the main focus of the thesis? Wed, 04 Oct 2023 11:15:09 +0200 https://news.ki.se/laura-fratiglioni-awarded-the-bengt-winblad-prize-2023 The prize is awarded annually by the Swedish Society of Medicine (SLS) to a person who has made outstanding contributions to Alzheimer's research. This year the Bengt Winblad Prize is awarded to Laura Fratiglioni, Professor of Medical Epidemiology with a focus on dementia diseases at the Department of Neurobiology, Care Sciences and Society, Karolinska Institutet. Tue, 19 Sep 2023 15:27:45 +0200 https://news.ki.se/new-link-between-increased-astrocytes-in-the-brain-and-blood-in-early-alzheimers-disease A new study shows that the activation of the brain's immune defense cells, astrocytes, in the early stages of Alzheimer's disease, could be tracked early with a brain PET scanner, and is linked to changes that can be detected in the blood later in the course of the disease. The study has now been published in Molecular Neurodegeneration. Tue, 12 Sep 2023 07:35:55 +0200 https://news.ki.se/new-thesis-on-mental-stimulation-to-prevent-alzheimers-disease Hi Anders Rydström, PhD student at the Division of Clinical Geriatrics. On September 8 you will defend your thesis ”Mental stimulation and multimodal trials to prevent cognitive impairment and Alzheimer's disease”, what is the main focus of the thesis? Wed, 23 Aug 2023 10:18:14 +0200 https://news.ki.se/new-thesis-on-the-impact-of-dietary-macronutrients-on-cognitive-health-among-older-adults Hi Jakob Norgren, PhD student at the Division of Clinical Geriatrics. On June 12 you will defend your thesis ”The impact of macronutritional composition and ketosis on cognitive health : from normal aging to Alzheimer’s disease”, what is the main focus of the thesis? Thu, 25 May 2023 14:40:18 +0200 https://news.ki.se/sugar-molecule-in-blood-can-predict-alzheimers Early diagnosis and treatment of Alzheimer’s disease requires reliable and cost-effective screening methods. Researchers at Karolinska Institutet have now discovered that a type of sugar molecule in blood is associated with the level of tau, a protein that plays a critical role in the development of severe dementia. The study, which is published in Alzheimer's & Dementia, can pave the way for a simple screening procedure able to predict onset ten years in advance. Wed, 12 Apr 2023 13:00:00 +0200 https://news.ki.se/researchers-propose-a-novel-biomarker-for-early-diagnosis-of-alzheimers-disease Alzheimer’s disease is the most prominent cause of dementia affecting millions of people worldwide. As the changes in the brain function starts 10-20 years before the clinical onset of Alzheimer’s disease, there is a strong interest in the identification of early markers that can be predictive of future mental health/cognitive decline. This may be something that some KI researchers are on the lookout for. Their latest study is now published in Nature Reviews Neurology. Tue, 28 Mar 2023 13:31:44 +0200 https://news.ki.se/new-thesis-on-subcellular-ab-mechanisms-and-treatment-strategies-in-alzheimer-disease Hi Yang Gao, PhD student at the Division of Neurogeriatrics. On February 24 you will defend your thesis "Alzheimer Disease: Subcellular Aβ mechanisms and treatment strategies", what is the main focus of the thesis? Tue, 31 Jan 2023 16:01:41 +0100 https://news.ki.se/the-same-genes-may-be-behind-cardiometabolic-diseases-and-dementia Being affected by several cardiometabolic diseases such as diabetes, heart disease and stroke, is linked to a greatly increased risk of dementia and Alzheimer’s disease. A new twin study by researchers from Karolinska Institutet suggests that the same genes may be behind the risk of both cardiometabolic diseases and dementia. The findings have been published in European Heart Journal. Thu, 12 Jan 2023 13:15:16 +0100 https://news.ki.se/the-proteins-that-fix-almost-everything Proteins can make any inventor green with envy. It is proteins that make the body work. But when these same super-substances make mistakes, we may get sick with things like cancer or Alzheimer's disease. The job of researchers is to sort out the proteins when they malfunction. Wed, 11 Jan 2023 15:14:56 +0100 https://news.ki.se/blood-based-markers-may-reveal-alzheimer-disease-ten-years-before-symptoms-show Alzheimer disease begins decades before any symptoms, such as memory loss, start to show. Consequently, early diagnosis increases the chances of slowing the disease down with drugs. A new study on an inherited form of the disease shows that a protein called GFAP is a possible biomarker for very early stages of the disease. The study, conducted by researchers at Karolinska Institutet and published in the journal Brain, could one day lead to an earlier detection of this serious and common disease. Wed, 11 Jan 2023 06:00:06 +0100 https://news.ki.se/cholinesterase-inhibitors-helped-alzheimers-patients-preserve-kidney-function Researchers from the Department of Neurobiology, Care Sciences and Society (Eriksdotter group) in collaboration with the Departments of MEB (Carrero group) and Clintec (Bruchfeld group) at KI have recently had their study published in Kidney International (IF 19). This paper is the first study linking activation of cholinergic anti-inflammatory pathways to kidney damage in humans. Mon, 05 Dec 2022 11:21:43 +0100 https://news.ki.se/a-new-study-about-the-effect-of-copper-ions-on-the-aggregation-of-the-alzheimers-associated-ab-peptide Researchers from Karolinska Institutet have reported new insights on how copper ions inhibit the aggregation of the amyloid-β peptide implicated in Alzheimer’s disease. The study published in JACS Au presents molecular structures of this complex, which provide a general understanding of the impact metal ions have. Thu, 17 Nov 2022 13:17:27 +0100 https://news.ki.se/bionut-researcher-receives-the-alzheimers-association-research-grant A researcher from the Department of Biosciences and Nutrition, Karolinska Institutet, has received a career supporting grant from the Alzheimer's Association. Thu, 22 Sep 2022 10:57:44 +0200 https://news.ki.se/repeated-serious-infections-linked-to-increased-risk-of-some-neurodegenerative-diseases Infections treated with specialty hospital care in early- and mid-life are associated with an increased subsequent risk of Alzheimer’s and Parkinson’s diseases, but not amyotrophic lateral sclerosis (ALS), according to a study by researchers from Karolinska Institutet, published in PLOS Medicine. Fri, 16 Sep 2022 11:57:59 +0200 https://news.ki.se/3d-imaging-helps-to-better-understand-the-early-stages-of-alzheimers-disease Using a novel 3D imaging technology, researchers at Karolinska Institutet, among others, have been able to comprehensively characterize a part of the brain that shows perhaps the earliest accumulation of tau protein, an important biomarker for the development of Alzheimer's disease. The results, published in the journal Acta Neuropathologica, may make it possible in the future to have a more precise neuropathological diagnosis of the Alzheimer’s disease spectrum at a very early stage. Wed, 31 Aug 2022 10:06:02 +0200 https://news.ki.se/agneta-nordberg-awarded The Alzheimer's Association® will present seven awards at the Alzheimer's Association International Conference® (AAIC®) 2022, recognizing researchers for their varied expertise, noteworthy achievements and innovative contributions to the field of Alzheimer's and dementia science. Agneta Nordberg, Division of Clinical Geriatrics, received one of them. Fri, 19 Aug 2022 13:46:01 +0200 https://news.ki.se/novel-way-to-diagnose-alzheimers-disease-by-blood-analysis Using proteomics and other advanced tools of molecular biology, an international team of researchers led by a group from Karolinska Institutet have found a novel way to diagnose Alzheimer’s disease by blood analysis, with a potential to uncover the underlying cause of the disease and prevent its development. Fri, 05 Aug 2022 15:53:04 +0200 https://news.ki.se/improved-protein-function-opens-way-for-new-drug-development-concept Researchers at Karolinska Institutet and SciLifeLab describe in a study published in Science how they have improved the ability of a protein to repair oxidative DNA damage and created a new protein function. Their innovative technique can lead to improved drugs for diseases involving oxidative stress, such as cancer, Alzheimer’s disease and lung diseases, but the researchers believe it has even greater potential. Thu, 23 Jun 2022 20:00:00 +0200 https://news.ki.se/target-protein-for-diabetes-drug-linked-to-reduced-risk-of-alzheimers-disease Mechanisms associated with a particular diabetes drug can also help to protect against Alzheimer’s disease, a study by researchers at Karolinska Institutet and published in Neurology reports. The results indicate that the drug’s target protein can be an interesting candidate for the treatment of Alzheimer’s disease. Thu, 02 Jun 2022 22:00:07 +0200 https://news.ki.se/a-historical-day-for-alzheimer-research-in-sweden On April 21, the 2nd Swedish Meeting for Alzheimer's Research was organized in Aula Medica by the Center for Alzheimer Research at NVS. In total, around 450 attendees participated, of which about 300 were researchers. Wed, 18 May 2022 16:25:15 +0200 https://news.ki.se/new-thesis-about-the-interplay-between-ab-metabolism-and-autophagy-in-ad Hi Richeng Jiang, PhD student at the Division of Neurogeriatrics, NVS. On May 30 you will defend your thesis ”Interplay between autophagy and amyloid beta metabolism in Alzheimer’s disease”, what's the main focus of the thesis? Thu, 12 May 2022 14:51:10 +0200 https://news.ki.se/hm-queen-silvia-visits-ki-during-alzheimer-conference On April 21, H.M Queen Silvia visited Karolinska Institutet to participate in a conference focusing on research on Alzheimer's disease, dementia and aging. Thu, 21 Apr 2022 14:01:12 +0200 https://news.ki.se/nvs-researchers-receive-funding-from-us-alzheimers-association-research-fellowship-aarf Amit Kumar and Agneta Nordberg, at the Division of Clinical Geriatrics (Nordberg Translational Molecular Imaging Lab), are awarded a grant of USD 175,000 USD over a four-year period for the project ”Understanding the role of synaptic loss in degenerative proteinopathies”. Tue, 30 Nov 2021 11:46:24 +0100 https://news.ki.se/early-accumulation-of-tau-in-the-brain-predicts-memory-decline-in-alzheimers-disease Researchers at Karolinska Institutet have compared how well different Alzheimer’s biomarkers predict the progression of the disease and its effect on the memory. They found that early accumulation of tau proteins in the brain as measured by PET scanner was more effective at predicting memory impairment than biomarkers in the cerebrospinal fluid or amyloid plaque in the brain. The results are published in the journal Molecular Psychiatry. Fri, 01 Oct 2021 02:00:05 +0200 https://news.ki.se/ki-researchers-awarded-156-million-us-dollar-nih-prime-grant-for-research-on-alzheimers-disease Docent Sara Hägg, together with a multidisciplinary team of KI researcher, has been awarded an NIH Prime Grant for their research on repurposing drugs for the primary prevention of Alzheimer’s Disease. The grant is for three years with the option to apply for additional two years. Mon, 13 Sep 2021 11:10:29 +0200 https://news.ki.se/link-between-adhd-and-dementia-across-generations A large study at Karolinska Institutet in Sweden has found a link between ADHD and dementia across generations. The study, published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, shows that parents and grandparents of individuals with ADHD were at higher risk of dementia than those with children and grandchildren without ADHD. Thu, 09 Sep 2021 13:00:06 +0200 https://news.ki.se/new-thesis-about-resolution-of-inflammation-in-alzheimers-disease-brain Hi there, Ceren Emre, PhD student at the Division of Neurogeriatrics! On September 1 you will defend your thesis ”Resolving inflammation - analysis of mechanisms in relation to Alzheimer pathology and aging”. What is the main focus of your thesis? Thu, 26 Aug 2021 09:00:44 +0200 https://news.ki.se/seven-researchers-at-nvs-receive-grants-from-the-swedish-brain-foundation-2021 This year, The Swedish Brain Foundation will distribute SEK 106 million in research grants. Karolinska Institutet is awarded 42% of these and includes seven researchers at the Department of Neurobiology, Health Sciences and Society (NVS) as recipients. Tue, 06 Jul 2021 15:32:52 +0200 https://news.ki.se/sex-and-gender-differences-in-dementia Center for Alzheimer Research (CAR) has started a working group on sex and gender differences in dementia. The group is led by Assistant professors Shireen Sindi and Daniel Ferreira at the Division for Clinical Geriatrics. It's their first working group and they are excited to see how this group will evolve. Fri, 04 Jun 2021 11:19:46 +0200 https://news.ki.se/new-thesis-about-neuroinflammation-and-its-resolution-in-alzheimers-disease Hi there, Ying Wang, PhD student at the Division of Neurogeriatrics! On June 23 you will defend your thesis “Neuroinflammation and its resolution in Alzheimer's disease". What is the main focus of your thesis? Fri, 04 Jun 2021 09:50:06 +0200 https://news.ki.se/joana-pereira-new-research-group-leader Joana Pereira officially starts as research group leader today, June 1, although she has been managing her own group for a while now. Tue, 01 Jun 2021 10:22:19 +0200 https://news.ki.se/new-thesis-about-novel-approach-to-treat-alzheimers-disease Hi there, Lorena Galán-Acosta, PhD student at the Division of Neurogeriatrics! On June 17 you will defend your thesis “Recombinant BRICHOS domains delivered over the blood-brain barrier : a possible way to treat Alzheimer's disease”. What is the main focus of your thesis? Wed, 26 May 2021 15:02:33 +0200 https://news.ki.se/new-thesis-about-the-heterogeneity-within-alzheimers-disease Hi there, Konstantinos Poulakis, PhD student at the Division of Clinical Geriatrics! On May 28 you will defend your thesis “Alzheimer’s disease heterogeneity assessment with MRI biomarkers and unsupervised statistical learning”. What is the main focus of your thesis? Tue, 11 May 2021 14:09:56 +0200 https://news.ki.se/possible-new-pet-tracer-for-early-detection-of-alzheimers New biomarkers for Alzheimer’s disease are a priority area for researchers seeking to learn more about the disease and find possible methods of early diagnosis. Researchers at Karolinska Institutet have now studied a new PET tracer that is an important diagnostic tool for the disease. The study on the tracer substance BU99008, which is published in Molecular Psychiatry, can play a key part in the early identification of signs of Alzheimer’s disease. Fri, 23 Apr 2021 02:00:05 +0200 https://news.ki.se/common-alzheimers-treatment-linked-to-slower-cognitive-decline Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer’s disease, but their effects on cognition have been debated and few studies have investigated their long-term effects. A new study involving researchers from Karolinska Institutet and published in the journal Neurology shows persisting cognitive benefits and reduced mortality for up to five years after diagnosis. Thu, 25 Mar 2021 16:07:12 +0100 https://news.ki.se/double-nvs-professor-lectures-via-zoom New professors Eric Westman and Dorota Religa, both Division of Clinical Geriatrics, head and deputy head of division respectively, gave their lectures as new professors at NVS on Wednesday January 20. Wed, 27 Jan 2021 15:23:47 +0100 https://news.ki.se/new-thesis-about-markers-of-synaptic-dysfunction-in-alzheimers-disease Hi Una Smailovic, PhD student at the Division of Clinical Geriatrics! On January 15 you will defend your thesis “Multimodal phenotyping of synaptic damage in Alzheimer’s disease : translational perspective with focus on quantitative EEG”. What’s the main focus of the thesis? Mon, 28 Dec 2020 10:37:20 +0100 https://news.ki.se/genetic-differences-important-for-alzheimers-diagnosis The two used methods for detecting amyloid pathology in Alzheimer's disease give ambiguous results, with the risk of incorrect or delayed care interventions. Now, researchers at Karolinska Institutet have found genetic explanations for the differences. The study is published in Molecular Psychiatry and may be important for more individual diagnostics and the development of future drugs. Fri, 11 Dec 2020 02:00:04 +0100 https://news.ki.se/professor-miia-kivipelto-wins-the-2020-ryman-prize The award recognises Professor Kivipelto’s more than 20 years of research into the prevention, diagnosis and treatment of cognitive impairment, Alzheimer’s Disease and dementia. Fri, 04 Dec 2020 08:00:02 +0100 https://news.ki.se/early-signs-of-alzheimers-disease-in-people-with-downs-syndrome Researchers at Karolinska Institutet have studied the incidence and regional distribution of Alzheimer’s disease biomarkers in the brains of people with Down’s syndrome. The results can bring new possibilities for earlier diagnosis and preventive treatment of dementia. The study is published in Molecular Neurodegeneration. Mon, 23 Nov 2020 06:00:04 +0100 https://news.ki.se/new-thesis-about-proteomics-in-alzheimer-disease Hi Hazal Haytural, PhD student at the Division of Neurogeriatrics, NVS! On November 27 you will defend your thesis “Unraveling pathogenic proteins and pathways in Alzheimer disease: A focus on proteomics”. What’s the main focus of the thesis? Wed, 11 Nov 2020 09:42:38 +0100 https://news.ki.se/ki-researchers-awarded-175-million-dollar-nih-prime-grant-for-research-on-alzheimers-disease Dr. Ivan Nalvarte, a Senior Researcher at the Department of Biosciences and Nutrition (BioNut) at Karolinska Institutet, has been awarded a grant of approximately 1.75 million US dollars for four years, from the National Institute of Health (NIH), USA. Fri, 18 Sep 2020 09:28:40 +0200 https://news.ki.se/professor-kivipelto-is-leading-the-first-global-initiative-for-prevention-of-dementia-and-alzheimers-disease World-Wide FINGERS (WW-FINGERS) is the first global network of clinical trials for risk reduction and prevention of dementia and Alzheimer's disease through multidomain interventions. The network convenes research teams from over 30 countries, and is led by Professor Miia Kivipelto from the Center for Alzheimer Research, Karolinska Institutet. The main scope, scientific strategy and activities of the WW-FINGERS network have been published today (July 6, 2020) in Alzheimer's & Dementia. Mon, 06 Jul 2020 09:45:01 +0200 https://news.ki.se/brain-imaging-can-predict-alzheimers-related-memory-loss Researchers at Karolinska Institutet have imaged tau protein in the brains of living patients with Alzheimer’s disease. The amount and spread of tau proved a predictor of future memory loss. Brain imaging for measuring tau can be useful both for improving diagnosis and for developing more effective treatments, say the researchers. The study is published in the journal Molecular Psychiatry. Fri, 03 Jul 2020 06:00:03 +0200 https://news.ki.se/new-thesis-about-drug-discovery-targeting-non-amyloid-pathways-in-alzheimers-disease Märta Dahlström, PhD-student at the Division of Clinical Geriatrics. On April 30, 2020 you will defend your thesis: "Drug discovery targeting non-amyloid pathways in Alzheimer’s disease", what's the main focus of the thesis? Mon, 27 Apr 2020 10:28:41 +0200 https://news.ki.se/maria-eriksdotter-receives-sek-82-million-in-grants-from-the-erling-persson-family-foundation She receives the grant for ”New diagnostic tools and treatment for Alzheimer's disease, traumatic brain injury and small vascular disease” and it is distributed over three years. Thu, 19 Dec 2019 08:49:54 +0100 https://news.ki.se/per-nilsson-receives-grants-from-torsten-soderbergs-foundation Per Nilsson, at the Division of Neurogeriatrics, NVS, receives 1 000 000 SEK in grants from Torsten Söderberg's Foundation. Fri, 13 Dec 2019 12:21:59 +0100 https://news.ki.se/proteins-on-viral-surface-linked-to-formation-of-alzheimers-plaque New research from Stockholm University and Karolinska Institutet shows that viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface. This coat of proteins makes the virus more infectious and facilitates the formation of plaques characteristic of neurodegenerative diseases such as Alzheimer's disease. The study is published in Nature Communications. Tue, 28 May 2019 08:26:07 +0200 https://news.ki.se/the-who-is-releasing-for-the-first-time-guidelines-on-risk-reduction-of-cognitive-decline-and-dementia Professor Miia Kivipelto and her team - the Nordic Brain Network - provided a major contribution to the development and definition of the guidelines, given the expertise and experience in the field of risk and protective factors for dementia and AD. Thu, 23 May 2019 15:50:01 +0200 https://news.ki.se/new-thesis-the-interplay-between-mitochondria-endoplasmic-reticulum-contacts-and-alzheimers-disease Fri, 22 Mar 2019 10:50:29 +0100 https://news.ki.se/speed-dating-when-alzheimers-researches-met Mon, 11 Feb 2019 15:16:27 +0100 https://news.ki.se/eleven-researchers-at-nvs-have-been-granted-alf-funds Thu, 15 Nov 2018 10:36:16 +0100 https://news.ki.se/finger-researchers-acknowledged-on-world-alzheimers-day Mon, 01 Oct 2018 08:52:48 +0200 https://news.ki.se/eurostars-eureka-financing-to-nvs-researchers Tue, 31 Jul 2018 13:36:12 +0200 https://news.ki.se/sleep-disturbances-linked-to-increased-dementia-risk Tue, 17 Jul 2018 08:00:00 +0200 https://news.ki.se/nordic-brain-researchers-in-cerebral-function-collaboration Mon, 07 May 2018 16:04:32 +0200 https://news.ki.se/new-cell-model-could-lead-to-treatments-for-neurological-diseases Researchers from Karolinska Institutet and KTH Royal Institute of Technology have developed a new cell model for human brain helper cells known as astrocytes. The model could potentially be used in large-scale drug screening in the search for treatments for neurological diseases such as Alzheimer’s. The research is published in the scientific journal Stem Cell Reports. Fri, 16 Feb 2018 09:02:08 +0100 https://news.ki.se/atlas-of-brain-blood-vessels-provides-fresh-clues-to-brain-diseases Wed, 14 Feb 2018 19:00:00 +0100 https://news.ki.se/calcium-transfer-may-open-up-to-new-ways-of-treating-alzheimers-disease Fri, 02 Feb 2018 13:52:40 +0100 https://news.ki.se/proteomics-analyses-could-present-new-opportunities-to-diagnose-and-treat-dementias Tue, 09 Jan 2018 09:00:00 +0100 https://news.ki.se/genes-behind-higher-education-linked-to-lower-risk-of-alzheimers Thu, 07 Dec 2017 09:02:16 +0100 https://news.ki.se/medical-nutrition-drink-may-affect-development-of-early-alzheimers Tue, 07 Nov 2017 13:53:32 +0100 https://news.ki.se/new-research-highlights-how-our-neurons-can-become-insulin-resistant-and-the-connection-to-alzheimer-disease Tue, 24 Oct 2017 14:52:28 +0200 https://news.ki.se/spread-of-tau-measured-in-the-brains-of-alzheimers-patients Tue, 16 May 2017 10:00:00 +0200 https://news.ki.se/biological-effects-and-therapeutic-potential-of-ngf-in-alzheimers Thu, 23 Feb 2017 16:26:23 +0100 https://news.ki.se/tau-vaccine-proves-successful-in-clinical-trial-on-alzheimers-disease Tue, 13 Dec 2016 15:25:42 +0100 https://news.ki.se/genes-responsible-for-risk-of-heart-attack-stroke-and-related-cardiometabolic-diseases-identified Fri, 19 Aug 2016 11:15:11 +0200 https://news.ki.se/promising-new-methods-for-early-detection-of-alzheimers-disease Fri, 08 Jul 2016 09:57:26 +0200 https://news.ki.se/imaging-of-tau-protein-holds-promise-in-alzheimers-disease Wed, 20 Apr 2016 21:41:22 +0200 https://news.ki.se/top-researchers-advocate-united-actions-to-fight-alzheimers-disease Tue, 15 Mar 2016 08:00:00 +0100 https://news.ki.se/inflammatory-changes-in-the-brain-twenty-years-before-alzheimer-onset Wed, 27 Jan 2016 08:00:00 +0100 https://news.ki.se/possible-biological-function-for-the-alzheimer-protein-amyloid-beta Tue, 03 Nov 2015 11:39:03 +0100 https://news.ki.se/feelings-of-hopelessness-may-increase-dementia-risk Wed, 14 Oct 2015 20:08:00 +0200 https://news.ki.se/healthy-diet-may-reduce-cognitive-decline-as-people-age Tue, 13 Oct 2015 11:14:38 +0200 https://news.ki.se/causal-link-between-telomere-shortening-and-alzheimers-disease In a newly published study, researchers at Karolinska Institutet show that the shortening of the telomeres – the caps at each end of the chromosomes in our cells – can be linked statistically to the active mechanism responsible for Alzheimer’s disease. Tue, 13 Oct 2015 09:47:22 +0200 https://news.ki.se/brichos-protein-may-prevent-brain-damage-in-alzheimers Mon, 16 Feb 2015 17:10:00 +0100 https://news.ki.se/promising-results-for-new-alzheimer-therapy Fri, 13 Feb 2015 09:00:00 +0100 https://news.ki.se/alzheimers-drug-reduces-risk-of-heart-attack Wed, 05 Jun 2013 00:00:00 +0200 https://news.ki.se/smaller-forms-of-amyloid-a-possible-target-for-alzheimers Fri, 15 Jun 2012 00:00:00 +0200 https://news.ki.se/alzheimers-vaccine-trial-a-success Wed, 06 Jun 2012 00:00:00 +0200