https://ki.se RSS News Listing https://news.ki.se/progress-in-stem-cell-therapy-for-type-1-diabetes Researchers at Karolinska Institutet and KTH Royal Institute of Technology have developed an improved method for creating insulin-producing cells from human stem cells. The results, published in Stem Cell Reports, demonstrate that these cells effectively regulate blood sugar levels in laboratory tests and can reverse diabetes in mice. Thu, 16 Apr 2026 17:00:08 +0200 https://news.ki.se/new-infrastructure-for-mrna-production-and-lipid-nanoparticle-formulation Karolinska ATMP Center, a collaboration between Karolinska Institutet and Karolinska University Hospital, has opened a new mRNA infrastructure at the pre-GMP facility on the Flemingsberg campus. This environment provides researchers and clinicians with the opportunity to produce mRNA and formulate it in lipid nanoparticles (LNPs) for research purposes. Mon, 16 Mar 2026 15:57:21 +0100 https://news.ki.se/cell-and-gene-therapy-from-science-fiction-to-the-hospital-ward Cell and gene therapies use the body’s building blocks – cells and genetic material – to boost the immune system or correct the root cause of disease. It is a new era in healthcare, in some cases offering the possibility of a cure where previously only relief or slowing of disease was possible. Fri, 09 Jan 2026 16:08:17 +0100 https://news.ki.se/the-phd-course-that-takes-cell-and-gene-therapy-from-bench-to-bedside In October 2025, Karolinska Institutet launched a brand-new two-week course giving PhD students a unique insight into how advanced therapy medicinal products (ATMPs), treatments based on cells, genes or tissues, are developed and manufactured. Mon, 08 Dec 2025 15:51:17 +0100 https://news.ki.se/stem-cell-therapy-reduces-fractures-in-children-with-congenital-brittle-bone-disease A new study from Karolinska Institutet and Karolinska University Hospital shows that stem cell therapy can reduce fractures by up to 78 per cent in children with the rare condition osteogenesis imperfecta (OI), also known as congenital brittle bone disease. Thu, 20 Nov 2025 10:55:59 +0100 https://news.ki.se/karolinska-atmp-center-behind-breakthrough-cancer-treatment A new form of CAR T-cell therapy has recently made headlines after a patient in a clinical trial became cancer-free in record time. The treatment was produced at Karolinska ATMP Center, a collaboration between Karolinska Institutet and Karolinska University Hospital. Production takes place at the affiliated manufacturing unit, Vecura. Thu, 06 Nov 2025 16:26:33 +0100 https://news.ki.se/new-memorandum-strengthens-leadership-in-cell-and-gene-therapies A new memorandum of understanding has been signed by Karolinska ATMP Center and the ATMP Center Uppsala to deepen their collaboration in the rapidly growing field of advanced therapy medicinal products (ATMPs), which includes cell- and gene-based medicines. The aim is to enhance joint capacity and competitiveness in the Stockholm–Uppsala region. Sun, 26 Oct 2025 22:01:52 +0100 https://news.ki.se/knut-steffensen-taking-cell-and-gene-therapy-from-the-lab-to-the-hospital Knut Steffensen heads up the newly opened Karolinska ATMP Centre, which has been established to convert research on cell and gene therapy into actual treatments. Equipped with experience from both academia and the pharmaceutical industry, he wants to combine the best of both worlds. Fri, 03 Oct 2025 11:14:03 +0200 https://news.ki.se/samir-el-andaloussi-receives-ssmfs-jubilee-prize-for-his-gene-therapy-research KI researcher Samir EL Andaloussi has been awarded the Swedish Society for Medical Research’s (SSMF) Jubilee Prize of SEK five million for his groundbreaking research in gene therapies that could revolutionise the treatment of hard-to-treat diseases. The recipient will also receive an honorary medal presented by H.M. The Queen on 17 October. Thu, 25 Sep 2025 14:09:18 +0200 https://news.ki.se/ki-and-st-erik-eye-hospital-expand-collaboration-on-advanced-therapies The Karolinska ATMP Center — a collaboration between Karolinska Institutet (KI) and Karolinska University Hospital — and St. Erik Eye Hospital have signed a letter of intent to strengthen their partnership in research, development, and clinical trials of cell- and gene-based medicines, known as Advanced Therapy Medicinal Products (ATMPs). The goal is to accelerate the transition from research to clinical application, particularly for retinal diseases that currently lack effective treatments. Thu, 04 Sep 2025 15:12:36 +0200 https://news.ki.se/preparations-for-the-first-car-t-treatment-for-multiple-myeloma-in-routine-healthcare Karolinska University Hospital has, for the first time in Sweden, begun preparations to treat a patient with multiple myeloma using CAR-T cell therapy in routine healthcare – an advanced form of immunotherapy where the patient's own T-cells are programmed to attack cancer cells. The treatment is aimed at patients who no longer respond to previous treatment options and offers new hope for a difficult-to-treat blood cancer. Mon, 23 Jun 2025 15:03:01 +0200 https://news.ki.se/promising-results-after-car-t-cell-therapy-for-leukemia-and-lymphoma Swedish cancer patients treated with CAR T-cell therapy show better survival rates and fewer side effects than seen in previous studies. This is shown in a new compilation of Swedish treatment results conducted by researchers in the SWECARNET network. Mon, 12 May 2025 16:11:06 +0200 https://news.ki.se/new-technology-facilitates-delivery-of-advanced-medicines Researchers at Karolinska Institutet have developed a technique that enables efficient delivery of therapeutic proteins and RNA to cells. The method, presented in Nature Communications, shows promising results in animal studies to deliver gene editors and protein therapeutics. Wed, 30 Apr 2025 13:11:52 +0200 https://news.ki.se/ki-researcher-takes-on-leading-role-in-european-cell-and-gene-therapy-organization Lindsay Davies, an researcher at Karolinska Institutet, has been elected Incoming Vice Chair for Europe within the International Society for Cell & Gene Therapy (ISCT), a global organization that brings together scientists, clinicians, regulators, and industry partners in the rapidly growing field of advanced therapies. Mon, 14 Apr 2025 13:48:01 +0200 https://news.ki.se/immunotherapy-for-liver-cancer-can-be-improved-with-new-insights-into-immune-cells T-cells from the liver and lymph nodes show promising potential for future treatments of liver cancer, according to a new study. Researchers at Karolinska Institutet have investigated how immune cells react to tumor-specific antigens in the complex environment surrounding liver cancer. Thu, 30 Jan 2025 09:30:27 +0100 https://news.ki.se/car-t-cell-therapy-is-here-to-stay Ten years ago, a cancer patient in Sweden was treated with CAR T-cell therapy for the first time. Today he is cured. Several challenges remain before the treatment can be given to everyone who could benefit from it, and how to achieve this was one of the questions discussed at the SWECARNET network’s annual education day. Tue, 17 Dec 2024 12:31:08 +0100 https://news.ki.se/nextgennk-and-ccrm-nordic-mini-symposium Advanced Medicinal Therapy Products, ATMP, span broadly over medical fields and the aim of this symposium is to enhance networking within ATMP and to get a flavor of academic and commercial development of ATMPs in Stockholm and Sweden. NextGenNK and CCRM Nordic are inviting you to a mini-symposium with the focus on ATMP on January 22, 2025. Tue, 10 Dec 2024 13:09:03 +0100 https://news.ki.se/knut-steffensen-becomes-new-director-of-karolinska-atmp-center On 4 November, Knut Steffensen will be taking up office as the director of the Karolinska ATMP Centre, a leading centre for advanced therapy medicinal products, with research, manufacture and treatment all under one roof. Sat, 19 Oct 2024 20:52:43 +0200 https://news.ki.se/gene-therapy-effective-in-hereditary-blindness Bothnia dystrophy is a form of hereditary blindness, prevalent in the region Västerbotten in Sweden. A new study at Karolinska Institutet published in Nature Communications shows that gene therapy can improve vision in patients with the disease. Tue, 10 Sep 2024 13:56:26 +0200 https://news.ki.se/bodys-message-in-a-bottle-delivers-targeted-cancer-treatment Researchers at Karolinska Institutet have succeeded in delivering targeted cancer treatment via small membrane bubbles that our cells use to communicate. A new study published in Nature Biomedical Engineering shows that the treatment reduces tumour growth and improves survival in mice. Mon, 20 May 2024 11:00:10 +0200 https://news.ki.se/sweden-signs-new-cooperation-agreement-with-the-us-on-cancer-research Sweden and the USA have previously enjoyed strong collaboration in the field of cancer care and research, and now it is further strengthened through a bilateral agreement. The purpose is to promote exchange between the two countries in both cancer research and the implementation of this research within cancer care, including both prevention and improved quality of life. Tue, 19 Mar 2024 16:38:56 +0100 https://news.ki.se/new-center-to-strengthen-investment-in-cell-gene-and-tissue-therapies Karolinska University Hospital's Director Björn Zoëga and Karolinska Institutet's President Annika Östman Wernerson have signed an agreement to establish a joint center for advanced cell, gene and tissue therapies. Wed, 12 Jul 2023 17:35:06 +0200