https://ki.se RSS News Listing https://news.ki.se/advice-for-hosting-visitors-at-kis-premises As a member of staff at KI, you play a vital role in preventing theft, vandalism and incidents that compromise safety on campus. Please follow the guidelines when receiving visitors at KI. Mon, 30 Mar 2026 15:22:49 +0200 https://news.ki.se/new-map-reveals-how-adult-brain-cells-remember-their-origins Researchers at Karolinska Institutet have created the first detailed map showing how genetic activity is controlled in individual cells of the adult human brain and spinal cord. The study, published in Nature Neuroscience, show that oligodendroglia, the cells that form the brain’s insulating myelin, retain an “epigenetic memory” of developmental programs long after these genes are no longer active. Thu, 19 Mar 2026 11:34:44 +0100 https://news.ki.se/rapid-sequencing-method-offers-same-day-detection-of-antibiotic-resistance Researchers at Karolinska Institutet have developed a rapid and cost efficient sequencing method that can identify antibiotic resistance within the same working day. The technique, called s5PSeq, measures how bacterial ribosomes respond within minutes after exposure to an antibiotic, offering a molecular readout of growth instead of waiting for traditional cultures. Mon, 16 Mar 2026 08:49:55 +0100 https://news.ki.se/promobilia-grant-supports-research-into-long-term-pain-relief A new research initiative at Karolinska Institutet aims to understand how chronic pain arises and how it might be switched off at its source. The project, “A Game-Changing Therapy for Lasting Pain Relief”, has now received support from the Promobilia Foundation. Fri, 13 Mar 2026 11:20:25 +0100 https://news.ki.se/researchers-at-karolinska-institutet-awarded-prestigious-postdoctoral-fellowships Two Marie Skłodowska-Curie Actions (MSCA) Postdoctoral Fellowships and a Walter-Benjamin-Postdoctoral Fellowship (German Research foundation, DFG) have been granted to outstanding early-career scientists at the Division of Molecular Metabolism (MolMet) at the Department of Medical Biochemistry and Biophysics. The fellowships are highly competitive and prestigious. Wed, 11 Mar 2026 18:22:40 +0100 https://news.ki.se/timing-found-to-be-crucial-for-spinal-cord-repair-in-zebrafish The healing of the spinal cord depends on carefully timed interactions between injured nerve cells and their surrounding environment, according to a new study published in Science Advances by researchers at Karolinska Institutet. Sat, 07 Mar 2026 10:03:04 +0100 https://news.ki.se/method-reveals-how-proteins-read-rna-messages Researchers at Karolinska Institutet have developed a technique that shows how proteins interact with RNA, the molecule that carries genetic instructions inside our cells. The study, published in Nucleic Acids Research, offers new insight into an important layer of gene regulation that can lead to better understanding of disease mechanisms. Thu, 05 Mar 2026 09:44:33 +0100 https://news.ki.se/new-alf-grant-boosts-cluster-headache-research New funding from Region Stockholm in collaboration with Karolinska Institutet will support advanced research into cluster headache at the university. By combining genetic studies with sleep and circadian rhythm research, the project seeks to improve care for a patient group with a high disease burden and risk of misdiagnosis. Tue, 03 Mar 2026 14:35:04 +0100 https://news.ki.se/how-dopamine-producing-neurons-arise-in-the-developing-brain In a new study from Karolinska Institutet, published in Nature Neuroscience, researchers have identified the neurogenic progenitor that give rise to dopaminergic neurons, the primary neurons affected in Parkinson’s disease. These findings could help improve how dopaminergic neurons are produced for transplantation in Parkinson’s disease. Mon, 16 Feb 2026 11:00:18 +0100 https://news.ki.se/traumatic-brain-injury-linked-to-long-term-risk-of-work-disability A Swedish study, recently published in the scientific journal Neurology, has found that individuals who have experienced a traumatic brain injury are more likely to face periods of work disability that can last for up to five years following the injury. Fri, 13 Feb 2026 13:23:59 +0100 https://news.ki.se/royal-medal-for-birgitta-henriques-normark Birgitta Henriques- Normark, at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet, has been awarded a medal, 12th size with the ribbon of the Order of the Seraphim, by HM the King. Thu, 05 Feb 2026 08:00:13 +0100 https://news.ki.se/ki-professor-birgitta-henriques-normark-discussed-vaccine-with-bill-gates Professor Birgitta Henriques-Normark, Gates Foundation awardee at the Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, met with Bill Gates when he visited Stockholm at the end of January. Mon, 02 Feb 2026 14:49:37 +0100 https://news.ki.se/neuro-researchers-receive-swedish-research-council-project-grants-in-medicine-and-health Among the 102 recipients at Karolinska Institutet who received research grants in medicine and health from the Swedish Research Council (Vetenskapsrådet), five researchers from the Department of Neuroscience were included. Tue, 27 Jan 2026 13:18:53 +0100 https://news.ki.se/saida-hadjab-awarded-novonordisk-grant-for-chronic-pain-and-headache-research KI researcher Saida Hadjab has been awarded funding from the Novo Nordisk Foundation for her project “A Game-Changing Therapeutic Target for Lasting Pain Relief”, which addresses a major unmet medical need in chronic pain and headache disorders. Designed to fast-track the commercialisation of cutting-edge research in sustainability and health, the grant aims to support bold innovations that have real-world impact. Mon, 26 Jan 2026 10:40:53 +0100 https://news.ki.se/new-access-cards-and-new-authorisation-system-in-2026 This spring, KI will begin replacing access cards (KI cards) and implementing a new system for managing access to premises – for a safer campus for both staff and students. The Professional Services (GVS) will be the first to replace cards, followed by the departments. Thu, 22 Jan 2026 14:28:33 +0100 https://news.ki.se/new-brain-maps-challenge-traditional-descriptions-of-the-brain For more than a century, maps of the brain have been based on how brain tissue looks under the microscope. These anatomical maps divide the brain into regions according to structural variations in the tissue. But do these divisions really reflect how the brain works? A new study on mice from Karolinska Institutet, published in Nature Neuroscience, suggests that this is often not the case. Tue, 20 Jan 2026 17:18:52 +0100 https://news.ki.se/federico-iovino-receives-novonordisk-foundation-grant-to-tackle-antimicrobial-resistance KI researcher Federico Iovino has been awarded the Pioneer Innovator Grant from the Novo Nordisk Foundation. Designed to fast-track the commercialisation of cutting-edge research in sustainability and health, the grant aims to support bold innovations that have real-world impact. Fri, 16 Jan 2026 16:03:38 +0100 https://news.ki.se/how-brain-waves-shape-our-sense-of-self A new study from Karolinska Institutet, published in Nature Communications, reveals how rhythmic brain waves known as alpha oscillations help us distinguish between our own body and the external world. The findings offer new insights into how the brain integrates sensory signals to create a coherent sense of bodily self. Mon, 12 Jan 2026 11:00:13 +0100 https://news.ki.se/in-memory-of-professor-tore-midtvedt Professor Tore Midtvedt, Oslo, passed away on December 2nd at the age of 91. He is mourned by his wife Kari, his sons Karsten, Per and Öyvind with their families, as well as a large circle of grandchildren, great-grandchildren and extended family. Fri, 19 Dec 2025 14:13:30 +0100 https://news.ki.se/important-information-regarding-year-end-closing-at-mtc We are approaching the annual closing of the books for 2025 and would like to take the opportunity to remind you of some important facts. Take notice of the deadlines both regarding HR and Finance. Thu, 11 Dec 2025 15:21:59 +0100 https://news.ki.se/ssmf-starting-grant-to-veijo-salo Veijo Salo, new research group leader at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet has received SSMF (Svenska Sällskapet för Medicinsk Forskning) starting grant 2025. Mon, 08 Dec 2025 15:47:24 +0100 https://news.ki.se/using-social-media-may-impair-childrens-attention Children who spend a significant amount of time on social media tend to experience a gradual decline in their ability to concentrate. This is according to a comprehensive study from Karolinska Institutet, published in Pediatrics Open Science, where researchers followed more than 8,000 children from around age 10 through age 14. Mon, 08 Dec 2025 06:05:10 +0100 https://news.ki.se/new-study-reveals-how-the-brain-prioritises-bodily-signals-in-conscious-awareness A new study shows that visual and tactile impressions that are related to our own body are prioritised for reaching conscious awareness. This helps us understand how we develop the feeling that the body is our own – through the brain’s integration of what we see and what we feel. Thu, 04 Dec 2025 13:25:45 +0100 https://news.ki.se/lucia-celebration-in-biomedicum-2 Welcome to the Lucia celebration in Biomedicum on Monday, December 15th at 3:00 PM in the atrium. Mon, 01 Dec 2025 13:56:11 +0100 https://news.ki.se/mbb-researchers-on-clarivates-list-of-highly-cited-researchers-2025 Gonçalo Castelo-Branco and Sten Linnarsson from the Department of Medical Biochemistry and Biophysics are on the Clarivate list of highly cited researchers in 2025. Thu, 27 Nov 2025 18:29:05 +0100 https://news.ki.se/over-sek-20-million-in-grants-to-mtc-from-the-swedish-research-council As part of the Swedish government’s long-term strategy and action plan to counteract and reduce virus outbreaks and pandemics, the Swedish Research Council is undergoing a ten-year national research programme in Viruses and Pandemics. In the latest funding round, researchers at the Department of Microbiology, Tumor and Cell Biology, have been granted over 20 million SEK. Thu, 27 Nov 2025 18:01:18 +0100 https://news.ki.se/over-25-million-sek-in-grants-to-mbb-researchers-from-swedish-cancer-society We congratulate the seven researchers at the Department of Medical Biochemistry and Biophysics, who have been awarded grants from the Swedish Cancer Society (Cancerfonden) for the period 2026-2028. Together, the MBB researchers are awarded grants of 25,6 million SEK. Wed, 26 Nov 2025 15:32:32 +0100 https://news.ki.se/new-microprotein-can-help-cancer-cells-overcome-stress In a new study published in the journal Nucleic Acids Research, a research team at Karolinska Institutet has performed a large-scale genetic screen to uncover the hidden roles of tiny proteins, so-called microproteins. Cell stress and protein misfolding are involved in many diseases, including cancer and neurodegenerative disorders, and the study could one day contribute to new therapeutic strategies. Wed, 26 Nov 2025 10:49:04 +0100 https://news.ki.se/ki-researchers-awarded-torsten-soderberg-grants-in-medicine The Torsten Söderberg Foundation recognises outstanding achievements in medicine through its annual grants. Two researchers from the Department of Neuroscience at Karolinska Institutet have been awarded grants in medicine to support their innovative research into brain health and infectious diseases. Wed, 26 Nov 2025 10:19:38 +0100 https://news.ki.se/study-reveals-unexpected-link-between-dopamine-and-serotonin-in-the-brain Researchers at Karolinska Institutet, Columbia University and the University of San Francisco, have uncovered a previously unknown mechanism by which dopamine, a key brain chemical vital for movement and motivation, can affect brain activity indirectly, by boosting serotonin. The study was recently published in Sciences Advances. Tue, 25 Nov 2025 11:21:19 +0100 https://news.ki.se/minister-lotta-edholm-visits-ki Minister for Upper Secondary School, Higher Education and Research Lotta Edholm visited KI on 12 November. While being escorted around the Biomedicum research building, speaking with researchers in multiple sclerosis and finding out more about precision medicine, she asked questions concerning animal experimentation and KI raised the issue of Ahmadreza Djalali, the KI researcher still incarcerated in Iran. Mon, 24 Nov 2025 19:08:30 +0100 https://news.ki.se/brain-circuit-controlling-compulsive-behaviour-mapped Researchers at Karolinska Institutet have identified a brain circuit that can drive repetitive and compulsive behaviours in mice, even when natural rewards such as food or social contact are available. The study has been published in the journal Science Advances and may contribute to increased knowledge about obsessive-compulsive disorder and addiction. Fri, 21 Nov 2025 20:00:09 +0100 https://news.ki.se/professor-emeritus-hugo-lagercrantz-receives-the-2025-ki-cultural-award KI president Annika Östman Wernerson honoured professor emeritus Hugo Lagercrantz with this years KI Cultural Award at a ceremony on November 6th. With this award KI celebrates individuals at KI whose efforts have brought culture and science together in meaningful ways - both within our university and in our engagement with society Wed, 12 Nov 2025 11:13:12 +0100 https://news.ki.se/in-memory-of-professor-ola-hermanson Professor Ola Hermanson, who served as a distinguished member of the neuroscience community at Karolinska Institutet, passed away on 2 October 2025 at the age of 60. His career was marked by scientific excellence, visionary leadership, and a deep commitment to the advancement of neuroscience both in Sweden and internationally. Tue, 11 Nov 2025 12:58:19 +0100 https://news.ki.se/fat-tissues-hidden-role-in-ovarian-cancer-spread In a new study published in Nature Communications, researchers at Karolinska Institutet and Queen Mary University of London have investigated how the physical structure of fat tissue helps ovarian cancer cells invade the body, offering potential new treatment strategies. Tue, 30 Sep 2025 09:37:58 +0200 https://news.ki.se/new-study-links-dna-replication-failure-to-cancer-therapy A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals from RB tumor suppressor proteins. The findings add a new layer to our understanding of how cancer drugs work and may lead to better targeted cancer therapies in the future. Tue, 16 Sep 2025 09:32:55 +0200 https://news.ki.se/hidden-complexity-in-blood-cancer-may-hold-key-to-better-treatments New research from Karolinska Institutet, published in Cell Reports Medicine, reveals that mantle cell lymphoma is more diverse than previously thought, highlighting the need for personalized therapies. Wed, 27 Aug 2025 18:30:14 +0200 https://news.ki.se/designing-novel-antibiotics-against-priority-pathogens-using-generative-ai Researchers at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet have co-authored a study published in Cell, which introduces a novel approach to antibiotic design using generative deep learning. The study, which is an international collaboration between Massachusetts Institute of Technology (MIT) and Karolinska Institutet, leverages deep learning to generate structurally novel antibiotics and proteomics to identify the cognate targets on a cell-wide scale. Fri, 15 Aug 2025 12:00:29 +0200 https://news.ki.se/genetic-study-show-that-common-blood-cancer-includes-subtypes A new study from Karolinska Institutet, published in Cell Reports Medicine, shows that follicular lymphoma (FL), a common type of blood cancer, is not one single disease but consists of three genetically distinct subtypes. The findings may help doctors diagnose and treat patients more accurately in the future. Fri, 15 Aug 2025 10:47:02 +0200 https://news.ki.se/fire-alarm-in-biomedicum-july-7 On July 7th at 12:19 PM, a fire alarm was triggered in the dining area C1012 due to smoke development in a microwave oven. The alarm required everyone in the atrium to evacuate to the assembly point (the area between Biomedicum and Aula Medica). The evacuation went smoothly, and no material damage or physical injuries occurred. Tue, 08 Jul 2025 09:47:30 +0200 https://news.ki.se/bjort-kragesteen-appointed-research-leader-of-the-future-by-ssf The Foundation for Strategic Research (SSF) has appointed Assistant Professor Bjørt Katrinardóttir Kragesteen at the Department of Medical Biochemistry and Biophysics as one of this year's Research Leaders of the Future. A total of 213 applications were received, of which 16 were selected. The researchers will receive a grant of SEK 15 million each over five years and will participate in a comprehensive leadership training program. Wed, 25 Jun 2025 09:52:55 +0200 https://news.ki.se/mapping-the-brain-in-the-gut-may-provide-clues-to-gastrointestinal-disorders Researchers at Karolinska Institutet have identified three types of nerve cells connected to the intestinal villi, suggesting that previously unknown neural networks regulate fluid balance in the gut. The findings, published in the journal Nature Neuroscience, could lead to a better understanding of diseases such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Thu, 29 May 2025 11:30:09 +0200 https://news.ki.se/children-discover-cell-biology-through-clay-at-karolinska-institutet Biomedicum was transformed into a colourful studio on May 26th when children rolled up their sleeves for a Science Clay Workshop that turned cell biology into art. Tue, 27 May 2025 13:37:14 +0200 https://news.ki.se/novo-nordisk-foundation-grant-for-ki-researcher-in-type-2-diabetes Amir Ata Saei, assistant professor at the Department of Microbiology, Tumor and Cell Biology has been awarded the Novo Nordisk Foundation Excellence Emerging Investigator Grant within Endocrinology and Metabolism 2025. Fri, 23 May 2025 15:23:15 +0200 https://news.ki.se/ki-professor-elected-as-international-member-of-the-us-national-academy-of-sciences Klas Kärre, Professor Emeritus of Molecular Immunology at the Department of Microbiology, Tumor and Cell Biology, has been elected as an international member of the US National Academy of Sciences. Tue, 06 May 2025 11:44:38 +0200 https://news.ki.se/tetracycline-antibiotics-impair-t-cell-function-by-targeting-mitochondria A team of international researchers led by Karolinska Institutet has revealed in unprecedented detail how tetracycline antibiotics impair T cell function by binding mitochondrial ribosomes and inhibiting oxidative metabolism (OXPHOS). The study, reported in Nature Communications, raises mechanistic considerations for antibiotic therapy and the design of new molecules that can better discriminate between pathogen and host. Mon, 05 May 2025 10:26:20 +0200 https://news.ki.se/regulatory-dna-links-cancer-and-tissue-regeneration A new study in Life Science Alliance reveals a key genetic connection between cancer susceptibility and tissue regeneration. Researchers at Karolinska Institutet identified a super-enhancer region upstream of the MYC gene essential for tumor development and tissue repair. Wed, 09 Apr 2025 09:41:39 +0200 https://news.ki.se/postdoctoral-fellowship-from-cancerfonden-awarded-to-dr-karolina-borankova Dr. Karolina Borankova, a member of Professor Nils-Göran Larsson's group at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet, has been awarded the prestigious Postdoctoral Fellowship from Cancerfonden. The project aims to investigate whether mitochondrial DNA mutations that affect mitochondrial function, impact lung cancer growth and tumor burden. Tue, 08 Apr 2025 13:21:26 +0200 https://news.ki.se/new-findings-could-improve-stroke-care Researchers at Karolinska Institutet have identified a new mechanism that may improve the treatment of ischemic stroke. The study, published in the Journal of Clinical Investigation, shows that the growth factor PDGF-CC and its receptor PDGFRα play a crucial role in scar formation in the brain after an ischemic stroke. Tue, 04 Mar 2025 15:30:58 +0100 https://news.ki.se/water-molecules-help-proteins-read-the-human-genome In a recently published study in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and Biophysics at Karolinska Institutet, have discovered that water molecules play a crucial role in helping proteins, specifically transcription factors, read and regulate the human genome. Fri, 14 Feb 2025 10:10:28 +0100 https://news.ki.se/patricia-colque-has-passed-away Patricia Colque, a long-time co-worker at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet, passed away earlier this week at the age of 77 years. Thu, 30 Jan 2025 13:54:29 +0100 https://news.ki.se/association-between-elevated-levels-of-vegf-b-and-impaired-kidney-function In diabetic kidney disease, fat accumulates in the kidneys, leading to lipotoxicity and kidney damage. A recently published study by Ulf Eriksson's research group at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet shows that elevated levels of the protein VEGF-B in the kidney and adipose tissue correlate with increased fat accumulation in the kidney and impaired kidney function in patients with diabetic kidney disease. Thu, 16 Jan 2025 15:50:42 +0100 https://news.ki.se/how-sars-cov-2-exploits-human-proteins-to-replicate Researchers at Karolinska Institutet have discovered how the SARS-CoV-2 virus, which causes COVID-19, manipulates human proteins to replicate and evade the immune system. The results have been published in the scientific journal Nature Communications. Thu, 05 Dec 2024 16:51:43 +0100 https://news.ki.se/t-cells-sent-into-space-in-unique-experiment On 26 November an experiment in a sounding rocket was launched at Esrange Space Center in Kiruna, Sweden by a research group at the Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet. The researchers aims to collect data for a study that examines how a type of immune cell, T cells, are affected by lack of gravity, called microgravity. Tue, 03 Dec 2024 13:01:37 +0100 https://news.ki.se/new-method-for-deep-plasma-proteome-profiling In a recent study published in Nature Communications, scientists at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet, in collaboration with Michigan State University, have introduced an innovative approach to improve plasma proteome profiling. The method enables the detection of low-abundance proteins in plasma. Fri, 08 Nov 2024 16:40:00 +0100 https://news.ki.se/new-insights-into-how-our-cells-process-rna-for-energy-production Researchers at the Department of Cell and Molacular Biology, Karolinska Institutet have made a major discovery in how human cells produce energy. Their study, published in the EMBO Journal, reveals the detailed mechanisms of how mitochondria process transfer RNA (tRNA) molecules, which are essential for energy production. Fri, 08 Nov 2024 15:40:07 +0100 https://news.ki.se/mitochondrial-dna-levels-impact-tumor-size A new collaborative study from Karolinska Institutet published in Science Advances shows that the levels of mitochondrial DNA (mtDNA) directly influence lung adenocarcinoma (LUAD) progression in mice. LUAD is a common subgroup of human lung cancer that typically contains high levels of mtDNA. The link between high mtDNA levels and tumor progression suggests that mtDNA may provide a new therapeutic target and a biomarker for stratifying patients. Mon, 04 Nov 2024 09:41:09 +0100 https://news.ki.se/professor-ernest-arenas-has-passed-away Ernest Arenas, professor at Karolinska Institutet, passed away on September 15th at the age of 62. Dr. Arenas was widely known both within and outside Sweden as one of the pioneers in Parkinson’s disease research, with a strong commitment to developing better treatment strategies through cell replacement therapy. Tue, 17 Sep 2024 08:24:45 +0200 https://news.ki.se/a-few-samples-reveal-imbalances-in-vaginal-health A new study published in Microbiome by researchers at Karolinska Institutet, suggests that a few well-timed samples could help predict long-term imbalances in vaginal health, which is linked to various health issues. Tue, 27 Aug 2024 12:32:38 +0200 https://news.ki.se/new-tool-pisa-rex-facilitates-drug-development Researchers have developed an industry-standard tool to facilitate drug development and translational research in collaboration between labs at Karolinska Institutet and the Gygi Lab at Harvard Medical School. Wed, 14 Aug 2024 10:48:20 +0200 https://news.ki.se/sign-up-on-our-new-e-mail-list-forum-biomedicum A new e-mail list is now available for everyone working in Biomedicum: Forum Biomedicum. Here you can share and receive information about equipment, cultural events at KI, get advices etc. Thu, 11 Jul 2024 16:06:14 +0200 https://news.ki.se/identification-of-novel-protein-involved-in-mitochondrial-gene-expression Researchers at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet characterize a novel GTPase involved in ribosome production in mitochondria. The study, published in Nature Communication, provides new insights into the process that enables mitochondria to produce energy. Mon, 08 Jul 2024 09:27:48 +0200 https://news.ki.se/findings-reveals-gut-microbes-arsenal-against-pathogens A study conducted by researcher Juan Du's research group at the Karolinska Institutet sheds light on the capabilities of our gut microbes and their metabolites. The findings reveal potent inhibitory effects on the growth of antibiotic-resistant bacteria and suggest interactions and signaling between gut microbes and pathogens. Mon, 03 Jun 2024 11:19:14 +0200 https://news.ki.se/camilla-bjorkegren-new-head-of-the-department-of-cell-and-molecular-biology Camilla Björkegren has been appointed Head of the Department of Cell and Molecular Biology (CMB), starting June 1, 2024. Mon, 20 May 2024 11:56:04 +0200 https://news.ki.se/leprosy-drug-may-be-effective-in-huntingtons-disease-study-suggests A preclinical study from Karolinska Institutet offers hope for treating severe neurodegenerative diseases with an existing drug. The study suggests that the leprosy drug clofazimine may be effective in the treatment of Huntington’s disease. Fri, 03 May 2024 09:42:44 +0200 https://news.ki.se/the-svedberg-prize-to-ki-researcher-bjorn-reinius The 2024 Svedberg Prize is awarded to Björn Reinius, Department of Medical Biochemistry and Biophysics at Karolinska Institutet, for his discoveries regarding the gene regulation mechanisms of the X chromosome and his substantial impact on COVID-19 clinical diagnostics. Wed, 27 Mar 2024 10:17:48 +0100 https://news.ki.se/new-technique-developed-for-targeted-protein-degradation A new publication in Nature Communications from researchers at Karolinska Institutet solves a long-standing problem by establishing a system that allows site-specific protein degradation within mitochondria, the cellular hubs for energy production and metabolism. Wed, 21 Feb 2024 14:13:58 +0100 https://news.ki.se/the-hilpda-protein-a-potential-biomarker-for-new-treatment-options-in-aggressive-kidney-cancer A new study from Karolinska Institutet discovered that blocking the MYC tumor protein in kidney cancer cells leads to an increase in fat droplets, which are associated with tumor growth. The study provides crucial knowledge for identifying new therapeutic targets for treating this aggressive form of cancer. Mon, 19 Feb 2024 13:47:53 +0100 https://news.ki.se/lisa-westerberg-appointed-professor Lisa Westerberg has been appointed Professor of Experimental Immunology at the Department of Microbiology, Tumor and Cell Biology from 1 January 2024. Mon, 22 Jan 2024 10:50:26 +0100 https://news.ki.se/learn-to-live-a-healthier-life-a-popular-science-workshop-by-lifestyle4health On Saturday, November 18th, the KI Network Lifestyle4Health welcomed the public to an informative afternoon at Medicinska Föreningen at Karolinska Institutet. The afternoon was filled with lectures, health marker measurements, and practical "patient cases" that participants could analyse to suggest recommendations for lifestyle changes. Fri, 22 Dec 2023 11:31:16 +0100 https://news.ki.se/isotopes-more-powerful-than-previously-thought In a recently published study, researchers at the Department of Medical Biochemistry and Biophysics (MBB) at Karolinska Institutet have questioned the old paradigm surrounding isotopes of light elements—carbon, hydrogen, nitrogen, and oxygen. These isotopes have now emerged as more powerful than one thought. Mon, 04 Dec 2023 11:24:13 +0100 https://news.ki.se/aspire-ii-award-to-researchers-at-ki The Mark Foundation for Cancer Research has awarded an 8 million SEK ASPIRE II Award to the Bennie Lemmens Research Group at the Department of Medical Biochemistry and Biophysics (MBB) at Karolinska Institutet. Supported by a previous ASPIRE I award, the team of Bennie Lemmens established state-of-the-art microscopy and DNA labeling techniques to study how human cells copy their DNA and respond to anticancer therapies, with unprecedented precision in time and space. Fri, 24 Nov 2023 14:01:43 +0100 https://news.ki.se/new-study-reveals-unexpected-consequences-of-crispr-cas9-gene-editing A new study by Claudia Kutter’s research group at the Department of Microbiology, Tumor and Cell Biology (MTC) has identified potential pitfalls in the use of the gene editing technique CRISPR-Cas9, a gene scissors that is used for cancer treatments. Tue, 21 Nov 2023 08:36:26 +0100 https://news.ki.se/the-consolidator-grant-from-the-swedish-research-council-awarded-to-georgios-sotiriou The Consolidator Grant within Medicine and Health from the Swedish Research Council has been awarded to Georgios Sotiriou at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet. The project aims to develop a holistic therapy of chronic wounds using nanoengineered solutions. Wed, 15 Nov 2023 12:17:06 +0100 https://news.ki.se/over-26-million-from-the-swedish-research-council-to-researchers-at-mbb In the Swedish Research Council (VR) latest call for medicine and health and natural and engineering sciences 2023, research grants of 26 197 750 SEK were distributed to six researchers at the Department of Medical Biochemistry and Biophysics for the years 2023-2028. Wed, 08 Nov 2023 13:44:46 +0100 https://news.ki.se/nanoclusters-of-insulin-can-control-insulin-activity A recently published study shows how nanoclusters of insulin can control insulin activity. The results can lead to new types of insulin drugs, senior author Ana Teixeira at the Department of Medical Biochemistry and Biophysics (MBB) at Karolinska Institutet, says. Mon, 09 Oct 2023 17:00:03 +0200 https://news.ki.se/allergy-study-on-wild-mice-challenges-the-hygiene-hypothesis The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis. Now, an article published in Science Immunology by researchers from Karolinska Institutet challenges this hypothesis by showing that mice with high infectious exposures from birth have the same, if not an even greater ability to develop allergic immune responses than 'clean' laboratory mice. Fri, 29 Sep 2023 20:00:05 +0200 https://news.ki.se/heavily-mutated-sars-cov-2-variant-ba286-not-as-resistant-to-antibodies-as-first-feared Researchers at Karolinska Institutet who studied SARS-CoV-2 variant BA.2.86, found that the new variant was not significantly more resistant to antibodies than several other variants that are circulating. The study also showed that antibody levels to BA.2.86 were significantly higher after a wave of XBB infections compared to before, suggesting that the vaccines based on XBB should provide some cross-protection to BA.2.86. Fri, 29 Sep 2023 15:19:21 +0200 https://news.ki.se/can-mrna-technology-disrupt-conventional-approaches-for-discovering-and-validating-in-vivo-new-therapeutic-targets Cardiogenic growth factors play important roles in heart development and in a new study published in the scientific paper Nature Communications from researchers at Karolinska Institutet shows how stem cell therapeutics and mRNA technology are beginning to converge offering major improvements in vascularization, survival, expansion, differentiation, and ultimately the function of human stem cell grafts. Fri, 08 Sep 2023 11:16:02 +0200 https://news.ki.se/new-study-questions-the-role-of-supercomplexes-in-metabolism-and-disease A new study published in Cell Metabolism by the research group of Professor Nils-Göran Larsson, at the Department of Medical Biochemistry and Biophysics, Karolinska Institutet, shows that so-called supercomplexes have no major role in cellular energy production and that altered levels therefore are unlikely to affect physiology and disease. Fri, 25 Aug 2023 17:05:04 +0200 https://news.ki.se/identification-of-a-direct-progenitor-population-for-differentiation-to-insulin-producing-cells The deficiency of functional insulin-producing cells is a common feature of type 1 and late-stage type 2 diabetes. Previous studies have suggested that mammals have very limited capacity for regeneration of insulin-producing cells, but researchers at Karolinska Institutet have found how zebrafish can form new cells and thereby provide clues to possible future possibilities in diabetes. The study is published in the scientific journal Science Advances. Mon, 21 Aug 2023 07:27:17 +0200 https://news.ki.se/grant-awarded-to-susanne-nylen-group-for-research-on-skin-related-neglected-tropical-diseases Susanne Nylén at the Department of Microbiology, Tumor and Cell Biology at KI, is leading a project that has been awarded a four-year grant from the Dutch foundation Dioraphte for research on the pathogenesis of post-kala-azar dermal leishmaniasis (PKDL) and leprosy. The total amount awarded is 850 000 euros. Fri, 18 Aug 2023 09:27:10 +0200 https://news.ki.se/new-mechanism-by-which-cancer-cells-survive-replication-stress Researchers from Karolinska Institutet have discovered a new molecular mechanism by which cancer cells safeguard themselves from oncogene-induced replication stress and propose a strategy to deactivate this protective mechanism. The study is published in the scientific journal Molecular Cell. Thu, 17 Aug 2023 13:15:14 +0200 https://news.ki.se/study-finds-a-new-biomarker-that-can-effect-therapy-for-the-treatment-of-various-cancers KI researcher Yihai Cao and his research group at the Department of Microbiology, Tumor and Cell Biology, have defined a new biomarker for predicting drug resistance of antiangiogenic therapy for the treatment of various cancers. The study is published in PNAS. Tue, 11 Jul 2023 08:21:24 +0200 https://news.ki.se/expanding-sorting-capacity-introducing-bfcs-upcoming-acquisition We are excited to announce that we are in the process of acquiring a new sorter for our Flow Cytometry Core Facility at Biomedicum. This acquisition aims to expand our sorting capacity, allowing us to better accommodate the needs of our researchers. Thu, 06 Jul 2023 11:30:21 +0200 https://news.ki.se/introducing-high-parameter-full-spectrum-flow-cytometry-at-the-bfc We are thrilled to announce the latest additions to our core facility. We have recently acquired two Sony ID7000 spectral analyzers, Alice and Howard. These analyzers are equipped with advanced features, including five lasers and an array of 147 detectors, enabling high-resolution spectral analysis. Thu, 06 Jul 2023 11:29:36 +0200 https://news.ki.se/progenitor-cells-offer-great-hope-for-heart-failure-patients The 5D Heart Patch Project, led by Prof Kenneth Chien, has identified human ventricular progenitor (HVP) cells that can create self-assembling heart grafts in vivo. The research has the potential to offer hope to millions of people suffering from heart failure. Fri, 21 Apr 2023 10:51:10 +0200 https://news.ki.se/young-researcher-from-karolinska-institutet-meets-nobel-laureates-in-germany Jelena Misic, PhD in Nils-Göran Larsson Group at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet, has been selected to participate in the Lindau Nobel Laureate Meetings in June 2023. Jelena studies different aspects of mitochondrial gene expression in mammals. Fri, 14 Apr 2023 10:06:14 +0200 https://news.ki.se/review-article-focuses-on-the-development-of-the-next-generation-of-drugs In a recently published article published in Nature Reviews Drug Discovery, Professor Yihai Cao’s research group at the Department of Microbiology, Tumor and Cell Biology, charts the information about drug development for the treatment of a number of human diseases by targeting new blood vessel formation. Thu, 13 Apr 2023 16:34:13 +0200 https://news.ki.se/jessica-alm-is-the-new-expert-coordinator-in-laboratory-and-diagnostic-surge-capacity-at-the-centre-for-health-crises The group of expert coordinators at the Centre for Health Crises keeps growing. The expert coordinators manage the work that is done within their field of expertise. The latest area of expertise to be added to the Centre is laboratory and diagnostic preparedness, with Jessica Alm as expert coordinator. Tue, 04 Apr 2023 10:30:35 +0200 https://news.ki.se/newsletter-from-fm-march-2023 The FM newsletter is sent to all employees working in Biomedicum about twice a semester and includes news from the Facility Management.  Wed, 29 Mar 2023 10:40:59 +0200 https://news.ki.se/simon-elsasser-awarded-the-svedberg-prize-2023 The Svedberg prize 2023 is awarded to Simon Elsässer, Department of Medical Biochemistry and Biophysics at Karolinska Institutet, for his contributions to our understanding of epigenetic gene regulation. Mon, 27 Mar 2023 15:58:43 +0200 https://news.ki.se/new-technology-maps-where-and-how-cells-read-their-genome A new study published in Nature reports that a technology known as spatial omics can be used to map simultaneously how genes are switched on and off and how they are expressed in different areas of tissues and organs. This improved technology, developed by researchers at Yale University and Karolinska Institutet, could shed light on the development of tissues, as well as on certain diseases and how to treat them. Wed, 15 Mar 2023 17:00:04 +0100 https://news.ki.se/first-detailed-description-of-helicobacter-infected-individuals The first detailed description of the microbiota and immune cells among asymptomatic Helicobacter pylori-infected individuals has been published by researchers at Karolinska Institutet. The results of the study will be instrumental to understand the complex microbiome and immunity network and provide new insights for asymptomatic Helicobacter pylori infection. Thu, 23 Feb 2023 10:03:12 +0100 https://news.ki.se/new-insights-into-a-fundamental-process-in-mitochondria Researchers at Karolinska Institutet uncover the function of the release factor mtRF1 in the final steps of mitochondrial protein synthesis. The study, published in Nature Communications, reveals new insights into a fundamental process in mitochondria. Wed, 04 Jan 2023 07:00:04 +0100 https://news.ki.se/simultaneous-mapping-of-several-different-epigenetic-landmarks-in-a-single-cell Researchers at Karolinska Institutet and Stockholm University have developed a new technology allowing simultaneous probing of several different histone marks in one individual cell and in thousands of cells at the same time. This new method allows to investigate in much greater detail how cells in the mouse brain acquire unique properties and specialize. The study is published in the journal Nature Biotechnology. Mon, 19 Dec 2022 17:00:04 +0100 https://news.ki.se/critical-illness-myopathy-common-condition-in-intensive-care-patients Critical illness myopathy (CIM) is a common complication affecting ventilator-treated intensive care patients, which can lead to increased mortality/morbidity, prolonged hospital care, impaired patient quality of life, and increased healthcare costs. reported molecular pathogenesis of CIM during prolonged ICU stay, and potential diagnostic biomarkers and therapeutic targets. The study was recently published in Journal of Cachexia, Sarcopenia and Muscle. Mon, 19 Dec 2022 10:16:36 +0100 https://news.ki.se/new-study-found-that-the-gene-scissor-leads-to-unexpected-genomic-changes The widely used gene scissor (CRISPR/Cas) can modify the genetic content in cells to study the molecular roles of genes and has gained great clinical relevance in gene therapy to treat genetic diseases. A new study performed by Claudia Kutter’s research group at the Department of Microbiology, Cell, and Tumor Biology at Karolinska Institutet, found that the gene scissor leads to unexpected genomic changes. Fri, 11 Nov 2022 16:14:50 +0100 https://news.ki.se/researchers-at-fyfa-and-mtc-receive-the-kiri-fellow-grant Researchers at Karolinska Institutet Qiaolin Deng and Georgios Sotiriou receive the KI Research Incubator (KIRI) Fellow postdoc grant 2022. The KIRI Fellow grant finances a postdoc for a collaborative interdisciplinary project. The awarded project aims to expand the use of tailored nanoparticles as drug carriers to deliver them to a dysfunctional placenta providing treatments to improve the child’s metabolic health. Thu, 27 Oct 2022 11:11:21 +0200 https://news.ki.se/covid-19-linked-to-excessive-destruction-of-connections-between-nerve-cells-in-new-brain-model Researchers at Karolinska Institutet have in a new study used cellular reprogramming to create human three-dimensional brain models and infected these models with SARS-CoV-2. In infected models, the brain immune cells excessively eliminated synapses and acquired a gene expression pattern mimicking what has been observed in neurodegenerative disorders. The findings could help to identify new treatments against persistent cognitive symptoms after a Covid-19 infection. Wed, 19 Oct 2022 13:49:59 +0200 https://news.ki.se/new-studies-shows-that-brown-fat-can-be-increased-by-stimulation-of-stem-cell-differentiation-in-the-adult-body Professor Yihai Cao, Department of Microbiology, Tumor and Cell biology, is the corresponding author of a study recently published in PNAS, explaining how brown adipose tissue (BAT) can be increased in the adult human body. Wed, 28 Sep 2022 18:02:37 +0200 https://news.ki.se/christina-johansson-new-head-of-administration-at-the-department-of-physiology-and-pharmacology As of August 2022 Christina Johansson is new head of administration at the Department of Physiology and Pharmacology (FyFa). Christina has worked in various roles and departments at KI since 2015, most recently as head of administration at the Unit for Teaching and Learning (UoL). Thu, 22 Sep 2022 08:07:01 +0200 https://news.ki.se/article-provides-evidence-that-energy-metabolism-and-biofilm-formation-regulation-are-intertwined-in-bacteria In a recently published article in the journal Trends in Microbiology, author Alberto J. Martin-Rodriguez, Senior Research Specialist at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet, explains how he found that distinct bacterial strains selectively use respiration for surface colonization. Tue, 06 Sep 2022 15:01:07 +0200 https://news.ki.se/new-publication-oxygen-responses-of-t-cells-alter-protection-against-tuberculosis In a new publication in Nature communications, Martin Rottenberg and Ruining Liu, professor and PhD student at the Department of Microbiology, Tumor and Cellbiology, explains how T cell protection against Tuberculosis is controlled by their oxygen responses. Tue, 06 Sep 2022 11:53:19 +0200 https://news.ki.se/new-study-cold-can-help-fight-cancer-growth New research from Yihai Cao research group at the Department of Microbiology, Tumor and Cellbiology, MTC, shows that the so-called brown fat in the human body seems to be able to prevent cancer tumors from growing. The result is published by Nature and has been widely disseminated in the media lately. Wed, 17 Aug 2022 15:49:57 +0200 https://news.ki.se/nitrogen-oxide-research-has-resulted-in-surprisingly-few-new-clinical-methods-and-treatments In a recently published review article in Cell, researchers Jon Lundberg and Eddie Weitzberg at the Department of Physiology and Pharmacology at Karolinska Institutet summarize research in nitric oxide (NO) with a focus on what is happening right now. Thu, 04 Aug 2022 17:00:08 +0200 https://news.ki.se/synaptic-connectivity-of-a-novel-cell-population-in-the-striatum A new study from the Department of Neuroscience at Karolinska Institutet characterises a novel neuronal population in the basal ganglia, responsible for the interaction between two types of neurotransmitters, GABA and acetylcholine. The study was recently published in Cell Reports. Wed, 25 May 2022 16:25:14 +0200 https://news.ki.se/cell-types-responsible-for-hearing-loss-in-humans-identified Using gene expression data from different cell types in the inner ear and brain, researchers have been able to identify the cell types that mainly contribute to hearing loss. The findings confirm that hearing loss does not derive from the brain but from a distinct compartment in the cochlea, called the stria vascularis, which is the “powerhouse” of the inner ear. The study has been published in the American Journal of Human Genetics. Mon, 16 May 2022 17:00:05 +0200 https://news.ki.se/heart-progenitors-spontaneously-regenerate-cardiac-muscle-in-salamanders Heart progenitors spontaneously regenerate cardiac muscle via a tight junction “honeycomb” in salamanders. Whether there are endogenous adult heart progenitors that can replenish damaged muscle cells remained controversial. Mon, 16 May 2022 12:07:16 +0200 https://news.ki.se/christopher-cederroth-in-kis-podcast-medicinvetarna Tinnitus is the experience of annoying sounds that no one else can hear, a kind of phantom sound. The problem is increasing, probably due to exposure to high noise levels. Fri, 11 Mar 2022 13:10:39 +0100 https://news.ki.se/new-publication-enterobacteria-impair-host-p53-tumor-suppressor-activity-through-mrna-destabilization The Selivanova's group at MTC recently established a multidisciplinary collaboration together with Dr. Marie-Stéphanie Aschtgen, microbiologist in the Henriques-Normark groups (also at MTC) to study the interplay between bacteria and cancer, focusing on how specific bacterial systems influence host tumor supressors. Together they recently got their first collaborative paper accepted in Oncogene, entitled "Enterobacteria impair host p53 tumor suppressor activity through mRNA destabilization". Tue, 01 Mar 2022 16:51:56 +0100 https://news.ki.se/rare-diseases-the-central-topic-of-spanish-state-visit On November 24, H.M. Queen Letizia of Spain, H.M. Queen Silvia and H.R.H. Crown Princess Victoria Karolinska Institutet and Karolinska University Hospital. Thu, 25 Nov 2021 11:32:28 +0100 https://news.ki.se/biofab-a-new-core-facility-at-biomedicum Biofabrication and Tissue Engineering (Biofab) is a new core facility at Biomedicum, Karolinska Institutet. Thu, 18 Nov 2021 17:39:55 +0100 https://news.ki.se/22-million-sek-in-grants-from-swedish-research-council-to-fyfa-researchers Six researchers at FyFa have been granted project funds from the Swedish research council to the amount of 22 million SEK. Thu, 18 Nov 2021 08:46:04 +0100 https://news.ki.se/federico-iovino-recognised-world-expert-by-expertscape Federico Iovino, Assistant Professor and group leader at the Department of Neuroscience, Karolinska Institutet, has been recognised "World Expert" in the field "Streptococcus pneumoniae” by Expertscape, a website that objectively ranks physicans, researchers and institutions by their expertise in more than 29,000 biomedical topics. Wed, 17 Nov 2021 16:33:21 +0100 https://news.ki.se/ellinor-kenne-receives-prestigious-award-master-in-memory-of-dan-grander-2021 Medicinska Föreningen (MF) in Stockholm is the largest student union at Karolinska Institutet. Every year MF awards a teacher with the award Mäster, to someone who has been teaching for an extended period of time, in an inspirational and pedagogical way or who initiated and implemented lasting improvements in the education. This year the award goes to Ellinor Kenne. It's the first time in a long time that someone at FyFa receives this award, and with the large amount of teaching that the departm Wed, 17 Nov 2021 10:34:37 +0100 https://news.ki.se/juleen-zierath-awarded-the-claude-bernard-medal-and-lectureship Professor Juleen R. Zierath receives the 2021 prestigious EASD Claude Bernard Award. This award recognizes an individual’s innovative leadership and lifetime achievements in diabetes research and is the EASD’s highest award. Thu, 30 Sep 2021 12:57:33 +0200 https://news.ki.se/fyfa-health-challange-we-help-each-other-getting-inspired Four questions to FyFa employees Rebecka Jakobsson, HR-partner and Duarte Ferreira, Assistant professor, about their experiences participating in FyFa Health Challange. Mon, 27 Sep 2021 08:51:04 +0200 https://news.ki.se/jill-ziesmer-interviewed-in-medicinvetarna-podcast-77 Jill Ziesmer, PhD student is interviewed in Karolinska institutets podcast Medicinvetarna no 77. The podcast is available on Spotify and podcasts.nu, among others. Wed, 22 Sep 2021 10:21:21 +0200 https://news.ki.se/security-information-due-to-thefts Unfortunately, there have been a number of thefts both from the bicycle garage and from other places in Biomedicum during the past month. We therefore ask you to think about locking your bikes and electric scooters properly, to not leave any valuables in the open, and call the Biomedicum security guard if you see anything suspicious or someone unauthorized in the building. Wed, 08 Sep 2021 15:07:20 +0200 https://news.ki.se/finding-the-t-cells-that-drive-nasal-polyp-growth Patients with chronic rhinosinusitis sometimes suffer from the growth of polyps in the nasal cavity. These polyps are difficult to treat and often require surgical intervention. Even after removal by surgery, polyps can return and present a significant health burden for patients. Mon, 23 Aug 2021 18:59:10 +0200 https://news.ki.se/prestigious-award-to-nicolas-pillon Assistant professor Nicolas Pillon at the Department of Physiology and Pharmacology, has been awarded the prestigious Novo Nordisk Foundation Future Leaders Award from the European Foundation for the Study of Diabetes (EFSD). Fri, 20 Aug 2021 10:39:20 +0200 https://news.ki.se/magnus-ingelman-sundberg-new-honorary-doctor-at-sdu Fyfa professor Magnus Ingelman- Sundberg has been appointed honorary doctor at the University of Southern Denmark. Thu, 19 Aug 2021 10:06:52 +0200 https://news.ki.se/ulf-von-euler-lecture-2021-with-professor-jeremy-nathans-0 This year Ulf von Euler lecture; "Molecular genetic studies of central nervous system vascular development and disease" is held by Professor Jeremy Nathans, Professor of molecular biology and genetics, neuroscience and ophthalmology at the Johns Hopkins University School of Medicine (Baltimore, MD. USA). He is also a Howard Hughes Medical Institute Investigator. Mon, 16 Aug 2021 10:04:10 +0200 https://news.ki.se/ki-researcher-gunnar-schulte-interviewed-in-dr-gpcr-podcast Gunnar Schulte, professor in receptor pharmacology at FyFa was interviewed by Dr Yamina Berchiche earlier this year in the podcast Dr. GPCR. Mon, 09 Aug 2021 13:50:53 +0200 https://news.ki.se/we-need-to-prevent-the-development-of-polycystic-ovary-syndrome In a recently published review article in Nature Reviews Endocrinology, two researchers at the Department of Physiology and Pharmacology at KI, concludes where the field of research is today regarding causes behind and development of, Polycystic Ovary Syndrome (PCOS) and how epigenetic processes can contribute to the development of the syndrome. Fri, 09 Jul 2021 13:57:44 +0200 https://news.ki.se/seeing-is-believing-a-snapshot-of-an-active-frizzled-renews-hope-for-finding-new-drugs New results presented by the Schulte lab at Karolinska Institutet in collaboration with researchers in Shanghai and Montréal, help us understand how the cell surface receptor FZD7 is activated and provides a platform for drug discovery to inhibit this process for therapeutic purposes. Thu, 08 Jul 2021 10:31:25 +0200 https://news.ki.se/andrea-carmine-belin-voted-to-join-the-international-headache-societys-board-of-trustees Andrea Carmine Belin, researcher at the Department of Neuroscience, has been nominated and elected to the International Headache Society's Board of Directors for a two-year period (2021-2023), which will also be announced in conjunction with the Members' Annual Meeting on September 9, 2021. Thu, 24 Jun 2021 15:37:22 +0200 https://news.ki.se/platinum-chemotherapy-can-enhance-the-treatment-resistance-of-ovarian-cancer-cells Researchers from Karolinska Institutet have discovered how platinum-chemotherapy can enhance the treatment resistance of ovarian cancer cells, by progressively changing the cancer cell-intrinsic adhesion signaling and cell-surrounding microenvironment. Wed, 23 Jun 2021 18:06:29 +0200 https://news.ki.se/research-sets-light-on-the-role-of-nitric-oxide-in-the-regulation-of-renal-function An article in Nature Reviews Nephrology summarizes the significant role of nitric oxide in the regulation of renal function and the link to cardiovascular disease and diabetes. Mattias Carlström, Associate Professor of Physiology at KI, is the author behind the article. Thu, 03 Jun 2021 10:47:42 +0200 https://news.ki.se/new-thesis-explores-the-development-and-diversity-of-proprioceptive-neurons Hi there, Haohao Wu, PhD student at the Department of Neuroscience at Karolinska Institutet! You will defend your thesis entitled "The molecular basis of the development and diversity of proprioceptive neurons : a story of surviving and thriving" on 21 May 2021. Tue, 18 May 2021 18:00:17 +0200 https://news.ki.se/new-insights-on-how-immune-cells-are-recruited-and-reprogrammed-to-drive-tumor-development Researchers at Karolinska Institutet show how a certain type of immune cells, macrophages, can be recruited into breast cancer tumors, where they are reprogrammed to support and drive tumor growth. In a study published in the scientific journal PNAS, they describe that low levels of the tumor suppressor protein TAp73 lead to hyperactivation of NFkB signaling and an inflammatory condition in breast cancer as well as secretion of molecules that recruit tumor-promoting macrophages into the tumor. Tue, 02 Mar 2021 09:36:17 +0100 https://news.ki.se/yihai-cao-new-fellow-and-member-of-the-american-institute-of-medicine-and-biological-engineering-aimbe AIMBE fellows represent two percent of the top scientists working in medicine and life science, and are regularly recognised for their contribution in teaching, research and innovation. Yihai Cao was recently elected to become one of them. Thu, 25 Feb 2021 14:23:15 +0100 https://news.ki.se/carl-sellgren-majkowitz-receives-swedish-foundations-starting-grant Swedish Foundations' Starting Grant 2020 is awarded to KI researcher, Carl Sellgren Majkowitz for his research in schizophrenia. Thu, 25 Feb 2021 13:29:51 +0100 https://news.ki.se/neurotrophins-critical-to-the-proper-functioning-of-the-prefrontal-cortex Researchers at Karolinska Institutet explain that the neurotrophin brain-derived neurotrophic factor (BDNF) binds to the receptor tropomyosin receptor kinase B (trkB) present on the surface of many neurons, triggering signaling pathways critical to the maturation and growth of neurons during development. In their latest article however, they show that BDNF-trkB signaling also plays a significant role in the functioning of the adult brain. Wed, 17 Feb 2021 09:48:27 +0100 https://news.ki.se/a-new-look-at-our-sixth-sense-the-sensory-link-between-our-movement-and-motor-control Researchers at Karolinska Institutet have revealed a large diversity of proprioceptive neurons and unveiled a new type of plasticity suggesting neuronal individuality in the nervous system to adapt its performance to changing environment. The article was recently published in Nature Communications. Mon, 15 Feb 2021 15:26:26 +0100 https://news.ki.se/an-inner-sensor-of-body-movement-revealed-in-zebrafish Researchers at Karolinska Institutet have revealed a central proprioceptive organ built directly into the central nervous system that acts as an inner movement sensor. The article was recently published in the Scientific Journal Neuron. Mon, 15 Feb 2021 09:05:05 +0100 https://news.ki.se/proteomic-analysis-reveals-when-and-how-which-proteins-are-degraded-in-cancer-cells-by-autophagy-pathways A fundamental process by which cellular components are degraded is Autophagy. Defects in Autophagy pathways are strongly associated with multiple human diseases, including neurodegenerative disorders and cancer. Despite their importance, to date, a comprehensive characterization of the extent and selectivity for Autophagic degradomes has remained largely uncharacterized. Researchers at Karolinska Institutet have in two studies published in the journal Autophagy mapped out how this happens. Wed, 20 Jan 2021 13:45:54 +0100 https://news.ki.se/gene-analysis-may-increase-the-effect-of-antidepressant-and-antipsychotic-drugs In a new study published in the journal JAMA Psychiatry, researchers at Karolinska Institutet have studied CYP2C19 and CYP2D6 genes impact on treatment with antidepressants and antipsychotic drugs. The study shows that a control of the patient’s genotype can be used to individualize the drug treatment and lead to a more effective treatment. Thu, 26 Nov 2020 14:23:35 +0100 https://news.ki.se/georgios-sotiriou-receives-the-2020-smoluchowski-award Georgios Sotiriou, Researcher at the Department of Microbiology, Tumor and Cell Biology receives the Smoluchowski award for his research contribution to the fields of aerosol science and technology. The award consists of a certification and a personal prize of 2.000 €. Mon, 12 Oct 2020 12:14:35 +0200 https://news.ki.se/inauguration-of-aimes-a-new-center-bridging-medicine-and-engineering-sciences The Center for the Advancement of Integrated Medical and Engineering Sciences, AIMES, is a collaboration between KTH Royal Institute of Technology and Karolinska Institutet, in partnership with Getinge, with the vision to enhance the exchange of expertise within academia and industry. The center was officially inaugurated on 30 September 2020, in Biomedicum, Solna (and via Youtube). Fri, 02 Oct 2020 17:37:03 +0200 https://news.ki.se/new-insights-on-how-own-body-perception-affects-self-concept How does our body affect the way we think about our personality? Would our sense of self change if one day our mind woke up, for example, inside the body of our best friend? A recent study published in the journal iScience shows that the above questions are no longer exclusively reserved for science-fiction movies. Wed, 26 Aug 2020 17:14:37 +0200 https://news.ki.se/vulnerable-human-spinal-motor-neurons-can-be-rescued-from-degeneration Researchers at Karolinska Institutet reveal mechanisms of neuron vulnerability and resistance in spinal muscular atrophy (SMA) by investigating gene activity dynamics of different neurons in a mouse model. The study was recently published in the journal Genome Research. Thu, 20 Aug 2020 19:05:03 +0200 https://news.ki.se/new-ways-to-study-how-cancer-arises In an interdisciplinary study combining stem cell biology and tumor biology, researchers from Karolinska Institutet (as well as Uppsala and Lund University, together with researchers in Canada, Germany and France), have succeeded in creating a new type of stem cell models for studies on cancer of the brain. The study was recently published in PNAS. Thu, 06 Aug 2020 16:07:52 +0200 https://news.ki.se/lower-pain-treshold-with-a-neandertal-gene The human perception of pain may have been influenced by events taking place 50,000-70,000 years ago when our ancestors met the Neanderthals. A Neanderthal gene confers increased sensitivity to pain according to new research from Karolinska Institutet and Max Planck Institute published in Current Biology. These findings could lead to more tailored treatments. Fri, 31 Jul 2020 08:43:45 +0200 https://news.ki.se/research-project-within-neuropsychoimmunology-receives-a-research-grant-from-hjarnfonden Sophie Erhardt's research group, at the Department of Physiology and Pharmacology Karolinska Institutet, has been awarded a research grant of in total SEK 1,200,000 from The Swedish Brain Foundation. Thu, 09 Jul 2020 09:27:56 +0200 https://news.ki.se/in-memory-of-the-late-professor-emeritus-torgny-h-svensson Professor emeritus Torgny Svensson has passed away following complications of covid-19 on Friday, June 12th, at the age of 75. He will be sorely missed by his family, as well as friends and colleagues in Sweden and around the world. Wed, 01 Jul 2020 15:27:16 +0200 https://news.ki.se/cell-stemness-is-maintained-upon-concurrent-expression-of-rb-and-the-mitochondrial-ribosomal-protein-s18-2 Researchers from Karolinska Institutet discovered that the retinoblastoma associated protein RB and the mitochondrial ribosomal protein S18-2 (MRPS18-2) play the essential roles in homeostasis of cell stemness. Rb1-/- mouse primary cells expressing both, S18-2 and RB exhibited a stem cell phenotype. Downregulation of S18-2 and RB in human mesenchymal stem cells resulted in decreased expression of stem cell-related genes. Loss of the S18-2 protein resulted in embryonic lethality in zebrafish. Wed, 24 Jun 2020 10:21:18 +0200 https://news.ki.se/hello-ingemar-ernberg-co-editor-of-the-book-kvantfysiken-och-livet Hello Ingmar Ernberg, co-editor and professor at the Department of Microbiology, Tumor- and Cell Biology (MTC). Congratulations to your new book “Kvantfysiken och livet” that has just been released. What is it all about? Tue, 26 May 2020 14:55:05 +0200 https://news.ki.se/finding-the-needle-in-the-haystack In a study recently published in Nature Methods, researchers from Karolinska Institutet and Oxford University have developed a method to identify molecules that are attached to proteins in the membrane. Wed, 13 May 2020 10:17:24 +0200 https://news.ki.se/hit-to-lead-studies-on-a-novel-series-of-small-molecule-inhibitors-of-dhodh The enzyme dihydroorotate dehydrogenase (DHODH), an essential component for the de novo pyrimidine ribonucleotide biosynthesis, has reemerged in the last few years as a target for the development of small molecules with anticancer and antiviral activity. Fri, 17 Apr 2020 12:03:05 +0200 https://news.ki.se/inflammation-makes-suppressive-lymphocytes-switch-role-to-support-autoimmunity Researchers from Karolinska Institutet in collaboration with a lab in San Antonio USA, have uncovered how a specific population of lymphocytes promotes autoimmune disease by giving up their regulatory role in the immune system. The newly discovered mechanism is published in PNAS from research led by Dr. Saikiran Sedimbi and Prof. Mikael Karlsson. Fri, 17 Apr 2020 08:29:14 +0200 https://news.ki.se/christopher-cederroth-receives-the-geraldine-dietz-fox-young-investigator-award-0 The Association for Research in Otolaryngology (ARO) announce Christopher Cederroth as the recipient for The Geraldine Dietz Fox Young Investigator Award at the 2020 ARO Annual MidWinter Meeting. Christopher Cederroth got the prestigious award for his hearing and tinnitus research. Tue, 07 Apr 2020 09:10:21 +0200 https://news.ki.se/barbara-canlon-awarded-with-the-hugh-knowles-prize The Hugh Knowles Prize for Distinguished Achievement is awarded periodically to individuals who have made outstanding contributions to research or clinical practice in the prevention, diagnosis, or treatment of hearing disorders. Tue, 10 Mar 2020 15:24:27 +0100 https://news.ki.se/chemotherapy-rewires-a-novel-resistance-promoting-signaling-pathway-in-ovarian-cancer Researchers from Karolinska Institutet along with clinicians from the Karolinska University Hospital have discovered a new molecular mechanism of cell oncogenic signaling switch, which is induced by platinum chemotherapy and contributes to treatment resistance in ovarian cancer. Wed, 04 Mar 2020 15:00:17 +0100 https://news.ki.se/pawel-kozielewicz-molecular-pharmacology-highlighted-trainee-author-january-2020 Congratulations Pawel Kozielewicz! You are the Highlighted Trainee Author for the January 2020 Issue of Molecular Pharmacology. Fri, 10 Jan 2020 13:14:27 +0100