News archive

MTC researcher Kaisa Lehti is featured on AcademiaNet, after a nomination by the Swedish Research Council.

Yvonne Brandberg will always remember the young man struck down by cancer in the prime of life. His fate motivated her to try to convince more people to sunbathe more sensibly.

Researchers in the Sonia lain and David Lane groups at MTC have recently published in the journal Nature Communications.

Professor Janne Lehtiö and coworkers at the department of Oncology-Pathology have published an article in Nature Communications describing their new Integrated Proteogenomics Analysis Workflow (IPAW). The method enables a more reliable identification of novel peptides.

Researchers at Karolinska Institutet have explored NK cell-based immunotherapy on patients with treatment-resistant leukaemia. The study, which is published in the scientific journal Clinical Cancer Research, shows that the new therapy is effective against several types of leukaemia.

A study published in Science Translational Medicine shows that small molecules that specifically inhibit an important selenium-containing enzyme may be useful in combating cancer. When researchers at Karolinska Institutet treated cancer in mice using these molecules, they observed rapid tumoricidal effects. Researchers now hope that this new principle for cancer treatment will eventually be developed for use in humans.

In a study published in Cell Chemical Biology this week, researchers from MTC (Michael Landreh, David Lane, Sonia Lain, Marcus Ladds et al), KTH, Uppsala University, and the University of Oxford, used a new strategy to find out how anticancer drugs bind to the membrane protein dehydroorotate dehydrogenase (DHODH), a new cancer target.

In a recent publication in Molecular Human Reproduction, researchers at OnkPat could identify the specific proteome profiling of mouse ovarian follicles at three different developmental stages. To do that, the researchers isolated the follicles and cultured them in vitro. This is the first protein mapping of ovarian follicles ever published.

MedTechLabs is now open – the research centre formed by a close collaboration between Karolinska Institutet (KI), the Royal Institute of Technology (KTH) and Stockholm County Council (SLL). The objective of the centre’s first project is to develop technology to improve diagnosis and treatment of patients who have, for example, suffered a stroke.

Researchers at OnkPat together with Italian researchers review recent studies on the acidic tumor environment and how this affects tumor growth and therapeutic efficacy.

When researcher and oncologist Peter Strang writes textbooks, he does so with a certain distance: everything is based on fact. Writing a novel requires a different kind of presence, such as for example trying to imagine what it is like to have been diagnosed with cancer and to be a patient.