News archive

Oskar Swartling from the Integrative Cardiovascular, Cancer and Ageing Research unit (ICCA), at the Departmet of Medicine, Huddinge (MedH) is defending his thesis titled "Progression of Chronic Kidney Disease: Risk Factors, Sex Differences and Intervention", on 23 May, 2025. Main supervisor is Ylva Trolle Lagerros (MedH).

Manne Godhe, PhD student at the Sports Medicine research group, the Department of Molecular Medicine and Surgery, will defend his thesis "Physical Activity and Fitness Measurements in Healthy Older Adults and Osteoarthrities Patients Undergoing Total Hip Arthroplasty" on May 23, 2025. Main Supervisor is Eva Andersson.

David Wulliman from Center for Infectious Medicine (CIM), at the Departmet of Medicine, Huddinge (MedH) is defending his thesis titled "T Cell Immunity Induced by SARS-CoV-2 and Flavivirus Vaccination", on 23 May, 2025. Main supervisor is Hans-Gustaf Ljunggren (MedH).

The combination of air pollution, dense urban development and limited green spaces increases the risk of asthma in both children and adults. This is shown by a new study conducted as part of a major EU collaboration led by researchers from Karolinska Institutet. The paper is published in Lancet Regional Health-Europe.

A study from Karolinska Institutet reveals how cells adapt to nutrient scarcity by altering their genetic instructions. This discovery, published in Molecular Cell, sheds light on cellular stress responses and opens up new medical treatments.

We would like to extend our heartfelt thanks to everyone who attended and presented at the very first Swedish Suicide Research Conference – a platform designed to promote high-quality, research-driven discussions on suicide and suicide prevention.

FyFa researcher Maria Lee has received a postdoctoral grant from the Knut and Alice Wallenberg Foundation: Wallenberg - Bienenstock Postdoctoral Fellowship Programme at Stanford. The grant funds two years of studies at Stanford.

The European Federation of Psychologists’ Associations (EFPA) has announced Professor Lars Bäckman, Karolinska Institutet, as the recipient of the Aristotle Prize 2025. This distinguished award recognises individuals who have made a substantial and original contributions to psychology, particularly in the field of cognitive ageing.

On Friday, 16 May, this spring’s doctoral degree conferment ceremony will take place in the Blue Hall at Stockholm City Hall, where newly conferred doctors and honorary doctors will be celebrated. Medical students Nora Khatibi and Gottfrid Rehnman are two of the evening’s marshals. Here, they share insights into their roles – and how they prepare for the event.

A new study published in JAMA Otolaryngology–Head & Neck Surgery has found that deficits in the sense of smell, known as olfactory impairment, are significantly associated with increased mortality in older adults. The findings, based on data from over 2,500 participants in the Swedish National Study on Aging and Care in Kungsholmen, suggest that olfactory testing could serve as a valuable early indicator of broader health decline.

Hi Anna Rennie, doctoral student at the Division of Clinical Geriatrics. On June 9 you will defend your thesis ”Does white matter matter? Neuroimaging in dementia with Lewy bodies and related conditions.” What is the main focus of the thesis?

Welcome to Signild Kvart´s defense of the thesis ”Non-standard employment and health: Exploring the pathways to health inequality” on May 16th.

Alexander Waldthaler from the Gastroenterology and Nutrition Unit (GUT), at the Departmet of Medicine, Huddinge (MedH) is defending his thesis titled "Advanced techniques in ERCP", on 23 May, 2025. Main supervisor is Annika Bergquist (MedH).

A new study in the European Heart Journal shows that people who develop type 1 diabetes in adulthood have an increased risk of cardiovascular disease and death, and that those diagnosed later in life do not have a better prognosis than those diagnosed earlier. The study, conducted by researchers at Karolinska Institutet, points to smoking, poor glucose control and obesity as the main risk factors.

Swedish Higher Education Authority (UKÄ) is satisfied with KI’s action report, following the thematic evaluation of the nursing programs, and considers the measures implemented by KI to be reasonable and appropriate.

Swedish cancer patients treated with CAR T-cell therapy show better survival rates and fewer side effects than seen in previous studies. This is shown in a new compilation of Swedish treatment results conducted by researchers in the SWECARNET network.

Björn Reinius and Joyce Noble have developed a synthetic protection for RNA molecules that is stable and can be stored at room temperature. Their innovation simplifies aspects of biomedical research and enables new analytical methods. They are now awarded the 2025 Prize for innovation and utilisation for their work.

In a recent study published in Developmental Cell, researchers at Karolinska Institutet created a comprehensive map of neuroblastoma at the cellular level by integrating single-cell transcriptomics, single-cell multi-omics, and spatial transcriptomics.

Pregnant women with metabolic dysfunction-associated steatotic liver disease (MASLD) have an increased risk of giving birth prematurely and the risk increase cannot be explained by obesity, according to a new study from Karolinska Institutet published in the journal eClinicalMedicine.

Hi there Clare Tazzeo! You will defend your thesis entitled "Investigating the interplay between frailty and healthcare utilization in older adults" on 26 May 2025. Could you tell us a little more?

A vitamin supplement that improves metabolism in the eye appears to slow down damage to the optic nerve in glaucoma. Promising results have been published in the journal Cell Reports Medicine. The researchers behind the study have now started a clinical trial on patients.

Bacterial resistance negates the effect of antibiotics in the treatment of infection. Using mouse models, researchers now show that if antibiotics are administered with an enzyme called endolysin, the combined effect protects against infection by resistant bacteria in all bodily organs – including the brain, which antibiotics alone have difficulty reaching. The results are reported in the journal Molecular Medicine.

Despite rapid advances in genome and exome sequencing, many individuals with rare diseases remain undiagnosed. In a Perspective article published in Nature Genetics, researchers at Karolinska Institutet highlight how long-read whole genome sequencing, LR-WGS, offers a paradigm shift in genetic testing.

The Docent Committee decided on the 29 of April 2025 to admit Kyla McKay as docent in public health, global health and social medicine.

A chance to welcome new KI students – in a paid role! We’re looking for students who want to work during the introduction week and at KI’s Welcome Days.

Dental professionals find it difficult to identify patients with severe dental anxiety. At the same time, patients are reluctant to talk about their fears and hope that the staff will understand anyway. This dilemma is described in a new thesis presented at the Department of Odontology at Karolinska Institutet.

Congratulations to Karl-Johan Malmberg, who has been awarded King Olav V's Cancer Research Prize for 2025. The prize is awarded annually to a researcher who has significantly improved the quality of Norwegian cancer research.

Klas Kärre, Professor Emeritus of Molecular Immunology at the Department of Microbiology, Tumor and Cell Biology, has been elected as an international member of the US National Academy of Sciences.

A new study from Karolinska Institutet in collaboration with BUP Stockholm has conducted a pilot evaluation of a family-based cognitive behavioral therapy for adolescents with suicidal behavior. The study, published in the scientific journal BMJ Mental Health, shows that the treatment Safe Alternatives for Teens and Youths (SAFETY) may be a promising option for reducing suicide attempts.

Researchers from Aging Research Center (ARC), Department of Neurobiology, Care Sciences and Society at Karolinska Institutet, in collaboration with National Family Care Competence Center (Nka), sent out a survey to 31,000 older adults to learn more about those that take care of a loved one, in or outside their homes. Turns out 2,157 people older than 65 years provide such care on a regular basis.

The 2025 Svedberg Prize is awarded to Michael Landreh, Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet, "for the development and innovative use of mass spectrometric tools that reveal hidden protein interactions."

A new project, supported by the Swedish Childhood Cancer Fund, aims to test hundreds of drugs simultaneously using advanced 3D cell models, despite limited sample material. The goal is to identify more treatment options for children with cancer, building on existing resources from GMS Childhood Cancer and the Swedish Childhood Tumor Biobank.

The Cozzarelli Prize recognises publications that reflect scientific excellence and originality. The 2024 prize for the best biomedical article in the Proceedings of the National Academy of Sciences (PNAS) has been awarded to MedH researcher Jakob Theorell.

In chronic lymphocytic leukemia (CLL), certain recurrent genetic alterations are known to influence disease progression and survival. One important abnormality is the loss of part of chromosome 11, del(11q), which is associated with a more aggressive disease course. However, it has remained unclear whether mutations in the ATM gene, which is also located in this region, have a similar impact.

KI researcher Pauliina Damdimopoulou is currently experiencing a lot of activity. At the end of April this year, she was appointed ERC ambassador — and just a few days later, she became a professor of reproductive biology at the Department of Women's and Children's Health. Now she looks forward to building new collaborations to strengthen research on women's and children's health.

A team of international researchers led by Karolinska Institutet has revealed in unprecedented detail how tetracycline antibiotics impair T cell function by binding mitochondrial ribosomes and inhibiting oxidative metabolism (OXPHOS). The study, reported in Nature Communications, raises mechanistic considerations for antibiotic therapy and the design of new molecules that can better discriminate between pathogen and host.

The Consortium Global IBD Visualization of Epidemiology Studies in the 21st Century (GIVES-21) now publish data on the global prevalence of inflammatory bowel disease (IBD) in Nature. Researchers from Karolinska Institutet have contributed to the study. While the number of people with incident IBD is relatively constant in Sweden, the prevalence is increasing and 1 per cent of the Swedish population is now estimated to have IBD.

Researchers at Karolinska Institutet have identified biomarkers in the blood associated with symptoms of long COVID, particularly severe respiratory disorders. The discovery can pave the way for future diagnosis and treatment. The results are published in the scientific journal Nature Immunology.

Researchers at Karolinska Institutet have developed a technique that enables efficient delivery of therapeutic proteins and RNA to cells. The method, presented in Nature Communications, shows promising results in animal studies to deliver gene editors and protein therapeutics.

A higher tax on cigarettes in low and middle-income countries can help to reduce child mortality, especially amongst the poorest children, a new study led by researchers at Karolinska Institutet and published in The Lancet Public Health suggests.

Researchers at Karolinska Institutet and Uppsala University have developed a powerful new technique to better understand how tiny molecules in our cells, called microRNAs, control which genes are turned on or off — a discovery that could improve how we study diseases from cancer to neurodevelopmental disorders.

Researchers at Karolinska Institutet have identified a new mechanism where circular RNA plays a crucial role in wound healing, which could lead to new therapies to improve wound healing and reduce scarring. The study was published in Advanced Science.

Robin Juthberg, PhD student at the Orthopaedic research group, the Department of Molecular Medicine and Surgery, will defend his thesis "Advancing neuromuscular electrical stimulation optimizing comfort and hemodynamic efficiency" on May 16th 2025. Main Supervisor is Paul Ackermann.

A newly published study involving researchers from Karolinska Institutet indicates that prostate cancer can be diagnosed at an early stage through a simple urine sample. With the aid of AI and extensive analyses of gene activity in tumours, they have identified new biomarkers of high diagnostic precision.

Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the immune system, called adaptive NK cells, to remember ovarian tumours and effectively attack them. The discovery, published in Cancer Immunology Research, could pave the way for new, more powerful immunotherapies for difficult-to-treat cancers.

A study from the Institute of environmental Medicine (IMM) at Karolinska Institutet shows that the chemical di(2-ethylhexyl) phthalate (DEHP), which is found in many plastic products, has clear negative effects on hormones and fertility endpoints relevant to female fertility.

They are among the first in Sweden to be vaccinated against the chikungunya virus - a vaccine that is the result of a discovery from their own laboratory.

Welcome to Suganthi Jaganathan´s defense of the thesis ”Applying novel methods to study long-term exposure to air pollution and temperature and annual mortality in India” on May 6th.

Congratulations to Mikael Rydén, the first Swede to be awarded the Camillo Golgi Prize.

Professor Jonas F Ludvigsson at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, and Örebro University Hospital has been awarded the Solstickepriset 2025.