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New professor at IMM
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Jiří Bártek, Professor of Cancer Biology at the Department of Medical Biochemistry and Biophysics researches the checkpoint systems that monitor cell division in our bodies. These systems are there to ensure that division occurs at the correct pace and to check the quality of DNA replication. Flaws in these controls can lead to cancer and affect ageing and immunity.
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Our sensitivity to harmful substances is determined by our genes. But such substances can also reprogram our DNA, so called epigenetic changes, in response to the environment. Karin Broberg, Professor of Environmental Medicine specialising in Genetics and Epigenetics at the Institute of Environmental Medicine, researches these links between heredity and environment.
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Karolinska Institutet's yearly installation ceremony was held Thursday October 15, 2015, at which new professors, adjunct professors, visiting professors and, not least, foreign adjunct professors were presented. This year's academic prizes and awards were also announced.
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Schizophrenia and other forms of psychosis cause terrible human suffering at a considerable cost to the health services. Christina Dalman's, Professor of Psychiatric Epidemiology at the Department of Public Health Science, work involves identifying the risk factors in order to understand how these conditions develop with a view to improving methods of therapy and prevention.
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Chronic pain affects large groups of patients and is very costly in terms of human suffering and medical resources. Eva Kosek, Professor of Clinical Pain Research specialising in Musculoskeletal Pain at the Department of Clinical Neuroscience, researches the causes of chronic pain in the hope that her work will one day lead to new, more efficacious treatments.
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Olli Kallioniemi, Professor of Molecular Precision Medicine, wants to see today’s great life-science advances put to much swifter clinical use. Both as a professor and as the new director of SciLifeLab he is interested in new translational collaborations and the molecular classification of diseases.
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Lisa Juntti-Berggren is Professor of Experimental Medicine at the Department of Molecular Medicine and Surgery and researches on diabetes, especially apolipoprotein CIII. She aims to find new drugs for the prevention and treatment of the disease.
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Bertrand Joseph, Professor of Molecular Cancer Biology specialising in Cell Death at the Institute of Environmental Medicine, researches signals at cellular level that determine if cells are to die or not. His work is relevant for many diseases, such as neurodegenerative diseases and cancer, in which cells take the wrong decision in this choice between life and death.
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Karin Loré, Professor of Vaccination Immunology specialising in Innate Immunity at the Department of Medicine, Solna, studies how the immune system responds to vaccination and how protective responses to infectious diseases are established. In particular, she focuses on how immune-stimulating substances – vaccine adjuvants – can induce stronger responses which is important for the development of vaccines to infections like hiv/aids and malaria.
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Single cell analysis enables scientists to do what was once thought impossible: study gene activity in an individual cell. Sten Linnarsson, Professor of Molecular System Biology specialising in Transcriptomics at the Department of Medical Biochemistry and Biophysics, uses the technique to identify cell types in the brain and to understand the systems that regulate our cells types in both healthy and cancerous tissue.
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Janne Lehtiö, Professor of Medical Proteomics at the Department of Oncology-Pathology, uses mass spectrometry to study proteomes and their function to understand how proteins change as cancer develops. One of his objectives is to find reliable biomarkers that can help doctors to choose the most effective medication for each patient.
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In a newly published study, researchers at Karolinska Institutet show that the shortening of the telomeres – the caps at each end of the chromosomes in our cells – can be linked statistically to the active mechanism responsible for Alzheimer’s disease.
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Sten Eirik Waelgaard Jacobsen, Professor of Stem Cell Biology and Regenerative Medicine at the Department of Medicine, Huddinge, and the Department of Cell and Molecular Biology, researches how bone marrow stem cells produce blood cells. His research involves exploring the mechanisms and regulation of healthy blood formation and the causes of diseases of the blood, such as leukaemia.
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Gert Helgesson, Professor of Medical Ethics at the Department of Learning, Informatics, Management and Ethics, researches scientific and medical ethics. The issues he interrogates concern everything from how researchers present their data to the difficult decisions doctors must make on life and death.
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The 2015 Nobel Prize in Chemistry has been awarded Tomas Lindahl, Paul Modrich and Aziz Sancar for having mapped, at a molecular level, how cells repair damaged DNA and safeguard the genetic information. Tomas Lindahl made these crucial discoveries, for which he is now being rewarded, at Karolinska Institutet.
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HIC at Stanford
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KI webbförvaltning
09-06-2023