Half-time seminars Half-time control Hemantha Mallapura

20-06-2022 9:00 am - 12:00 pm Add to iCal
Karolinska University Hospital, Solna Sjögren-rummet, R5, Floor 2, Karolinska University Hospital and Online

Title: Automated microfluidic-based production of PET radioligands for clinical and preclinical use

Principal Supervisor 

Research Specialist Sangram Nag, Department of Clinical Neuroscience, Karolinska Institutet 


Professor Christer Halldin, Department of Clinical Neuroscience, Karolinska Institutet 

Professor Bengt Långström, Department of Chemistry, Uppsala University

Vice VD Ludovic Le Meunier, PMB-Alcen, Frankrike 

Half-time reveiw board 

Professor Nicole Pamme, Department of Materials and Environmental Chemistry, Stockholm University

Dr. Johnny Vercouillie, School of Pharmacie, University of Tours 

Dr. Philip Miller, Department of Chemistry, Imperial College London 

Brief description

This project aims to produce clinically applicable Positron Emission Tomography (PET) radioligands with carbon-11 (11C), fluorine-18 (18F) and gallium-68 (68Ga) isotopes using a microfluidic cassette-based iMiDEV™ automated radiosynthesizer for clinical and preclinical applications. In addition, developing and optimizing experimental conditions for [11C]methyl iodide synthesis ([11C]CH3I) using a non-thermal plasma method and [11C]CH3I is one of the most used methylating agents in 11C radiochemistry.


Hemantha Mallapura Phd Student