Lectures and seminars CIM Seminar series - “Adipose tissue – a treasure box for discoveries”

Speaker

Matthias Blüher, professor of Molecular Enocrinology, Department of Medicine University of Leipzig.

The Blüher lab research is focused on the role of adipose tissue function and distribition in insulin resistance, the development of type 2 diabetes and other metabolic and cardiovascular diseases. Matthias established a large adipose tissue bank from well-phenotyped individuals which supported the functional characterization and translation of association signals for type 2 diabetes and obesity traits into molecular, cellular and physiological mechanisms.

Title

"Adipose tissue – a treasure box for discoveries".

Host

Niklas Björkström, CIM, Department of Medicine, Huddinge, KI.

Online meeting

You can join the seminar online via Zoom.

Meeting ID: 628 1653 1732
Passcode: 091171

Relevant publications:

1. Dong, H., Sun, W., Shen, Y., Baláz, M., Balázová, L., Ding, L., Löffler, M., Hamilton, B., Klöting, N., Blüher, M. and Neubauer, H., 2022. Identification of a regulatory pathway inhibiting adipogenesis via RSPO2. Nature metabolism, 4(1), pp.90-105.
2. Müller, T.D., Blüher, M., Tschöp, M.H. and DiMarchi, R.D., 2022. Anti-obesity drug discovery: Advances and challenges. Nature Reviews Drug Discovery, 21(3), pp.201-223.
3. Dommel, S., Hoffmann, A., Berger, C., Kern, M., Klöting, N., Kannt, A. and Blüher, M., 2021. Effects of whole-body adenylyl cyclase 5 (Adcy5) deficiency on systemic insulin sensitivity and adipose tissue. International journal of molecular sciences, 22(9), p.4353.
4. Landgraf, K., Klöting, N., Gericke, M., Maixner, N., Guiu-Jurado, E., Scholz, M., Witte, A.V., Beyer, F., Schwartze, J.T., Lacher, M., Villringer, A… Blüher, M., Kiess M. and Körner A.  2020. The obesity-susceptibility gene TMEM18 promotes adipogenesis through activation of PPARG. Cell Reports, 33(3), p.108295.
5. Blüher, M., 2019. Obesity: global epidemiology and pathogenesis. Nature Reviews Endocrinology, 15(5), pp.288-298.